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Protein

Cell division activator CedA

Gene

cedA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Activates the cell division inhibited by chromosomal DNA over-replication.

Miscellaneous

In vitro, binds double-stranded DNA, but not single-stranded DNA.

GO - Molecular functioni

  • double-stranded DNA binding Source: EcoCyc

GO - Biological processi

  • cell cycle Source: UniProtKB-KW
  • cell division Source: UniProtKB-KW
  • regulation of cell division Source: EcoCyc

Keywordsi

Molecular functionDNA-binding
Biological processCell cycle, Cell division

Enzyme and pathway databases

BioCyciEcoCyc:G6936-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division activator CedA
Gene namesi
Name:cedA
Synonyms:ydjP
Ordered Locus Names:b1731, JW1720
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13992 cedA

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000894711 – 80Cell division activator CedAAdd BLAST80

Proteomic databases

PaxDbiP0AE60
PRIDEiP0AE60

Interactioni

Protein-protein interaction databases

BioGridi4260304400 interactors.
DIPiDIP-47928N
IntActiP0AE60 14 interactors.
STRINGi316385.ECDH10B_1869

Structurei

Secondary structure

180
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni30 – 32Combined sources3
Beta strandi36 – 39Combined sources4
Beta strandi42 – 46Combined sources5
Beta strandi49 – 51Combined sources3
Beta strandi53 – 55Combined sources3
Beta strandi59 – 61Combined sources3
Helixi62 – 74Combined sources13

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BN8NMR-A1-80[»]
2D35NMR-A19-80[»]
ProteinModelPortaliP0AE60
SMRiP0AE60
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0AE60

Family & Domainsi

Sequence similaritiesi

Belongs to the CedA family.Curated

Phylogenomic databases

eggNOGiENOG4105R8J Bacteria
ENOG4111YYN LUCA
HOGENOMiHOG000267901
KOiK15722
OMAiHAIKMDA

Family and domain databases

Gene3Di3.30.730.201 hit
HAMAPiMF_01580 CedA, 1 hit
InterProiView protein in InterPro
IPR038463 CedA-like_sf
IPR019666 Cell_div_activator_CedA
PfamiView protein in Pfam
PF10729 CedA, 1 hit

Sequencei

Sequence statusi: Complete.

P0AE60-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKPLRQQNR QIISYVPRTE PAPPEHAIKM DSFRDVWMLR GKYVAFVLMG
60 70 80
ESFLRSPAFT VPESAQRWAN QIRQEGEVTE
Length:80
Mass (Da):9,377
Last modified:June 12, 2007 - v2
Checksum:i69CFC7E3EF709D72
GO

Sequence cautioni

The sequence BAE76513 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74801.2
AP009048 Genomic DNA Translation: BAE76513.1 Different initiation.
PIRiC64932
RefSeqiNP_416245.2, NC_000913.3

Genome annotation databases

EnsemblBacteriaiAAC74801; AAC74801; b1731
BAE76513; BAE76513; BAE76513
GeneIDi946235
KEGGiecj:JW1720
eco:b1731
PATRICifig|511145.12.peg.1802

Similar proteinsi

Entry informationi

Entry nameiCEDA_ECOLI
AccessioniPrimary (citable) accession number: P0AE60
Secondary accession number(s): P76211, Q2MB43
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: June 12, 2007
Last modified: March 28, 2018
This is version 91 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome