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Protein

Bacterioferritin-associated ferredoxin

Gene

bfd

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Seems to associate with BFR; could be a general redox and/or regulatory component participating in the iron storage mobilization functions of BFR. Could participate in the release or the delivery of iron from/to bacterioferritin (or other iron complexes).

Cofactori

[2Fe-2S] clusterNote: Binds 1 [2Fe-2S] cluster.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi4 – 41Iron-sulfur (2Fe-2S)By similarity
Metal bindingi6 – 61Iron-sulfur (2Fe-2S)By similarity
Metal bindingi39 – 391Iron-sulfur (2Fe-2S)By similarity
Metal bindingi42 – 421Iron-sulfur (2Fe-2S)By similarity

GO - Molecular functioni

  • 2 iron, 2 sulfur cluster binding Source: EcoCyc
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

2Fe-2S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG11181-MONOMER.
ECOL316407:JW3299-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Bacterioferritin-associated ferredoxin
Gene namesi
Name:bfd
Synonyms:yheA
Ordered Locus Names:b3337, JW3299
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11181. bfd.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6464Bacterioferritin-associated ferredoxinPRO_0000064914Add
BLAST

Proteomic databases

PaxDbiP0AE56.

Interactioni

Subunit structurei

Monomer.

Protein-protein interaction databases

BioGridi4262467. 8 interactions.
IntActiP0AE56. 1 interaction.
STRINGi511145.b3337.

Structurei

3D structure databases

ProteinModelPortaliP0AE56.
SMRiP0AE56. Positions 1-57.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105W53. Bacteria.
COG2906. LUCA.
HOGENOMiHOG000262408.
InParanoidiP0AE56.
KOiK02192.
OMAiREIMQDE.
PhylomeDBiP0AE56.

Family and domain databases

InterProiIPR007419. BFD-like_2Fe2S-bd_dom.
[Graphical view]
PfamiPF04324. Fer2_BFD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AE56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYVCLCNGIS DKKIRQAVRQ FSPHSFQQLK KFIPVGNQCG KCVRAAREVM
60
EDELMQLPEF KESA
Length:64
Mass (Da):7,363
Last modified:December 6, 2005 - v1
Checksum:i38D645EB15F7DE9E
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti9 – 91I → V in strain: ECOR 30.
Natural varianti22 – 243SPH → HPQ in strain: ECOR 30.
Natural varianti30 – 301K → R in strain: ECOR 30.
Natural varianti43 – 431V → I in strain: ECOR 30.
Natural varianti51 – 511E → Q in strain: ECOR 30.
Natural varianti57 – 571L → M in strain: ECOR 30.
Natural varianti63 – 631S → I in strain: ECOR 30.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M27176 mRNA. Translation: AAC13986.1.
AF058450 Genomic DNA. Translation: AAC14287.1.
U18997 Genomic DNA. Translation: AAA58134.1.
U00096 Genomic DNA. Translation: AAC76362.1.
AP009048 Genomic DNA. Translation: BAE77954.1.
PIRiJV0033. QQECB7.
RefSeqiNP_417796.1. NC_000913.3.
WP_000289085.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76362; AAC76362; b3337.
BAE77954; BAE77954; BAE77954.
GeneIDi947836.
KEGGiecj:JW3299.
eco:b3337.
PATRICi32122106. VBIEscCol129921_3430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M27176 mRNA. Translation: AAC13986.1.
AF058450 Genomic DNA. Translation: AAC14287.1.
U18997 Genomic DNA. Translation: AAA58134.1.
U00096 Genomic DNA. Translation: AAC76362.1.
AP009048 Genomic DNA. Translation: BAE77954.1.
PIRiJV0033. QQECB7.
RefSeqiNP_417796.1. NC_000913.3.
WP_000289085.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AE56.
SMRiP0AE56. Positions 1-57.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262467. 8 interactions.
IntActiP0AE56. 1 interaction.
STRINGi511145.b3337.

Proteomic databases

PaxDbiP0AE56.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76362; AAC76362; b3337.
BAE77954; BAE77954; BAE77954.
GeneIDi947836.
KEGGiecj:JW3299.
eco:b3337.
PATRICi32122106. VBIEscCol129921_3430.

Organism-specific databases

EchoBASEiEB1168.
EcoGeneiEG11181. bfd.

Phylogenomic databases

eggNOGiENOG4105W53. Bacteria.
COG2906. LUCA.
HOGENOMiHOG000262408.
InParanoidiP0AE56.
KOiK02192.
OMAiREIMQDE.
PhylomeDBiP0AE56.

Enzyme and pathway databases

BioCyciEcoCyc:EG11181-MONOMER.
ECOL316407:JW3299-MONOMER.

Miscellaneous databases

PROiP0AE56.

Family and domain databases

InterProiIPR007419. BFD-like_2Fe2S-bd_dom.
[Graphical view]
PfamiPF04324. Fer2_BFD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBFD_ECOLI
AccessioniPrimary (citable) accession number: P0AE56
Secondary accession number(s): O68930, P13655, Q2M702
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: September 7, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.