Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Gamma-glutamylcyclotransferase family protein YtfP

Gene

ytfP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in antibiotic biosynthesis.Curated

Caution

Lacks the conserved Glu residue at position 70 that serves as proton acceptor in enzymes with gamma-glutamylcyclotransferase activity.Curated

Enzyme and pathway databases

BioCyciEcoCyc:G7876-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Gamma-glutamylcyclotransferase family protein YtfP
Gene namesi
Name:ytfP
Ordered Locus Names:b4222, JW4181
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12516 ytfP

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001847891 – 113Gamma-glutamylcyclotransferase family protein YtfPAdd BLAST113

Proteomic databases

PaxDbiP0AE48
PRIDEiP0AE48

Interactioni

Protein-protein interaction databases

BioGridi4260673, 12 interactors
IntActiP0AE48, 1 interactor
STRINGi316385.ECDH10B_4417

Structurei

Secondary structure

1113
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 5Combined sources4
Turni14 – 16Combined sources3
Helixi17 – 20Combined sources4
Beta strandi23 – 37Combined sources15
Beta strandi39 – 49Combined sources11
Beta strandi51 – 57Combined sources7
Helixi60 – 70Combined sources11
Beta strandi76 – 83Combined sources8
Beta strandi86 – 93Combined sources8
Beta strandi101 – 105Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XHSNMR-A1-113[»]
ProteinModelPortaliP0AE48
SMRiP0AE48
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0AE48

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4108ZHD Bacteria
COG2105 LUCA
HOGENOMiHOG000261862
InParanoidiP0AE48
OMAiIESGNWL
PhylomeDBiP0AE48

Family and domain databases

CDDicd06661 GGCT_like, 1 hit
InterProiView protein in InterPro
IPR009288 AIG2-like
IPR013024 GGCT-like
IPR036568 GGCT-like_sf
PfamiView protein in Pfam
PF06094 GGACT, 1 hit
SUPFAMiSSF110857 SSF110857, 1 hit

Sequencei

Sequence statusi: Complete.

P0AE48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIFVYGSLR HKQGNSHWMT NAQLLGDFSI DNYQLYSLGH YPGAVPGNGT
60 70 80 90 100
VHGEVYRIDN ATLAELDALR TRGGEYARQL IQTPYGSAWM YVYQRPVDGL
110
KLIESGDWLD RDK
Length:113
Mass (Da):12,866
Last modified:December 6, 2005 - v1
Checksum:iA320C9DC94607CF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA Translation: AAA97119.1
U00096 Genomic DNA Translation: AAC77179.1
AP009048 Genomic DNA Translation: BAE78223.1
PIRiS56448
RefSeqiNP_418643.1, NC_000913.3
WP_001219160.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77179; AAC77179; b4222
BAE78223; BAE78223; BAE78223
GeneIDi948741
KEGGiecj:JW4181
eco:b4222
PATRICifig|1411691.4.peg.2478

Entry informationi

Entry nameiYTFP_ECOLI
AccessioniPrimary (citable) accession number: P0AE48
Secondary accession number(s): P39323, Q2M683
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health