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Protein

Protein AroM

Gene

aroM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

This protein of unknown function is encoded by a gene that cotranscribes with the aroL gene, which codes for shikimate kinase II.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG10083-MONOMER.
ECOL316407:JW0381-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein AroM
Gene namesi
Name:aroM
Ordered Locus Names:b0390, JW0381
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10083. aroM.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 225225Protein AroMPRO_0000064680Add
BLAST

Proteomic databases

PaxDbiP0AE28.

Interactioni

Protein-protein interaction databases

BioGridi4260783. 12 interactions.
IntActiP0AE28. 3 interactions.
STRINGi511145.b0390.

Structurei

3D structure databases

ProteinModelPortaliP0AE28.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105HBA. Bacteria.
ENOG410XSID. LUCA.
HOGENOMiHOG000117533.
InParanoidiP0AE28.
KOiK14591.
OMAiDRIIPPL.

Family and domain databases

InterProiIPR010843. Uncharacterised_AroM.
[Graphical view]
PfamiPF07302. AroM. 1 hit.
[Graphical view]
ProDomiPD037589. AroM. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

P0AE28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASLAILTI GIVPMQEVLP LLTEYIDEDN ISHHSLLGKL SREEVMAEYA
60 70 80 90 100
PEAGEDTILT LLNDNQLAHV SRRKVERDLQ GVVEVLDNQG YDVILLMSTA
110 120 130 140 150
NISSMTARNT IFLEPSRILP PLVSSIVEDH QVGVIVPVEE MLPVQAQKWQ
160 170 180 190 200
ILQKSPVFSL GNPIHDSEQK IIDAGKELLA KGADVIMLDC LGFHQRHRDL
210 220
LQKQLDVPVL LSNVLIARLA AELLV
Length:225
Mass (Da):24,917
Last modified:December 6, 2005 - v1
Checksum:i7A53C5B4AC7142A2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti152 – 1521L → W in AAA83835 (PubMed:3001025).Curated
Sequence conflicti155 – 1551S → R in AAA83835 (PubMed:3001025).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M13045 Genomic DNA. Translation: AAA83835.1.
U73857 Genomic DNA. Translation: AAB18114.1.
U00096 Genomic DNA. Translation: AAC73493.1.
AP009048 Genomic DNA. Translation: BAE76171.1.
X76979 Genomic DNA. Translation: CAA54283.1.
PIRiF64767. BVECAM.
RefSeqiNP_414924.1. NC_000913.3.
WP_001276420.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73493; AAC73493; b0390.
BAE76171; BAE76171; BAE76171.
GeneIDi945045.
KEGGiecj:JW0381.
eco:b0390.
PATRICi32115921. VBIEscCol129921_0402.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M13045 Genomic DNA. Translation: AAA83835.1.
U73857 Genomic DNA. Translation: AAB18114.1.
U00096 Genomic DNA. Translation: AAC73493.1.
AP009048 Genomic DNA. Translation: BAE76171.1.
X76979 Genomic DNA. Translation: CAA54283.1.
PIRiF64767. BVECAM.
RefSeqiNP_414924.1. NC_000913.3.
WP_001276420.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AE28.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260783. 12 interactions.
IntActiP0AE28. 3 interactions.
STRINGi511145.b0390.

Proteomic databases

PaxDbiP0AE28.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73493; AAC73493; b0390.
BAE76171; BAE76171; BAE76171.
GeneIDi945045.
KEGGiecj:JW0381.
eco:b0390.
PATRICi32115921. VBIEscCol129921_0402.

Organism-specific databases

EchoBASEiEB0081.
EcoGeneiEG10083. aroM.

Phylogenomic databases

eggNOGiENOG4105HBA. Bacteria.
ENOG410XSID. LUCA.
HOGENOMiHOG000117533.
InParanoidiP0AE28.
KOiK14591.
OMAiDRIIPPL.

Enzyme and pathway databases

BioCyciEcoCyc:EG10083-MONOMER.
ECOL316407:JW0381-MONOMER.

Miscellaneous databases

PROiP0AE28.

Family and domain databases

InterProiIPR010843. Uncharacterised_AroM.
[Graphical view]
PfamiPF07302. AroM. 1 hit.
[Graphical view]
ProDomiPD037589. AroM. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiAROM_ECOLI
AccessioniPrimary (citable) accession number: P0AE28
Secondary accession number(s): P08403, P77758, Q2MC35
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: December 6, 2005
Last modified: September 7, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.