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Protein

AMP nucleosidase

Gene

amn

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.UniRule annotation

Catalytic activityi

AMP + H2O = D-ribose 5-phosphate + adenine.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
AMP nucleosidaseUniRule annotation (EC:3.2.2.4UniRule annotation)
Gene namesi
Name:amnUniRule annotation
Ordered Locus Names:Z3139, ECs2779
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000645871 – 484AMP nucleosidaseAdd BLAST484

Proteomic databases

PRIDEiP0AE13

Interactioni

Protein-protein interaction databases

STRINGi155864.Z3139

Structurei

3D structure databases

ProteinModelPortaliP0AE13
SMRiP0AE13
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AMP nucleosidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105FYV Bacteria
COG0775 LUCA
HOGENOMiHOG000156781
KOiK01241
OMAiRPHAWIM

Family and domain databases

Gene3Di3.30.1730.10, 1 hit
HAMAPiMF_01932 AMP_nucleosidase, 1 hit
InterProiView protein in InterPro
IPR037109 AMP_N_sf
IPR011271 AMP_nucleosidase
IPR018953 AMP_nucleoside_Pase_N
IPR000845 Nucleoside_phosphorylase_d
IPR035994 Nucleoside_phosphorylase_sf
PANTHERiPTHR43691:SF6 PTHR43691:SF6, 1 hit
PfamiView protein in Pfam
PF10423 AMNp_N, 1 hit
PF01048 PNP_UDP_1, 1 hit
SUPFAMiSSF53167 SSF53167, 1 hit
TIGRFAMsiTIGR01717 AMP-nucleosdse, 1 hit

Sequencei

Sequence statusi: Complete.

P0AE13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNKGSGLTP AQALDKLDAL YEQSVVALRN AIGNYITSGE LPDENARKQG
60 70 80 90 100
LFVYPSLTVT WDGSTTNPPK TRAFGRFTHA GSYTTTITRP TLFRSYLNEQ
110 120 130 140 150
LTLLYQDYGA HISVQPSQHE IPYPYVIDGS ELTLDRSMSA GLTRYFPTTE
160 170 180 190 200
LAQIGDETAD GIYHPTEFSP LSHFDARRVD FSLARLRHYT GTPVEHFQPF
210 220 230 240 250
VLFTNYTRYV DEFVRWGCSQ ILDPDSPYIA LSCAGGNWIT AETEAPEEAI
260 270 280 290 300
SDLAWKKHQM PAWHLITADG QGITLVNIGV GPSNAKTICD HLAVLRPDVW
310 320 330 340 350
LMIGHCGGLR ESQAIGDYVL AHAYLRDDHV LDAVLPPDIP IPSIAEVQRA
360 370 380 390 400
LYDATKLVSG RPGEEVKQRL RTGTVVTTDD RNWELRYSAS ALRFNLSRAV
410 420 430 440 450
AIDMESATIA AQGYRFRVPY GTLLCVSDKP LHGEIKLPGQ ANRFYEGAIS
460 470 480
EHLQIGIRAI DLLRAEGDRL HSRKLRTFNE PPFR
Length:484
Mass (Da):53,995
Last modified:December 6, 2005 - v1
Checksum:iADC2FD95CC220527
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG57045.1
BA000007 Genomic DNA Translation: BAB36202.1
PIRiA85823
C90976
RefSeqiNP_310806.1, NC_002695.1
WP_001060244.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG57045; AAG57045; Z3139
BAB36202; BAB36202; BAB36202
GeneIDi912716
KEGGiece:Z3139
ecs:ECs2779
PATRICifig|386585.9.peg.2911

Similar proteinsi

Entry informationi

Entry nameiAMN_ECO57
AccessioniPrimary (citable) accession number: P0AE13
Secondary accession number(s): P15272, P78074
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: April 25, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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