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Protein

UPF0092 membrane protein YajC

Gene

yajC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11096-MONOMER.
ECOL316407:JW0397-MONOMER.

Protein family/group databases

TCDBi3.A.5.1.1. the general secretory pathway (sec) family.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0092 membrane protein YajC
Gene namesi
Name:yajC
Ordered Locus Names:b0407, JW0397
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11096. yajC.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei19 – 3921HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • cell envelope Sec protein transport complex Source: EcoCyc
  • integral component of plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 110110UPF0092 membrane protein YajCPRO_0000097013Add
BLAST

Proteomic databases

EPDiP0ADZ7.
PaxDbiP0ADZ7.
PRIDEiP0ADZ7.

Interactioni

Subunit structurei

Part of the SecDF-YidC-YajC translocase complex; YajC is also present in a homooligomeric complex in excess of the other components.1 Publication

Protein-protein interaction databases

BioGridi4263532. 351 interactions.
DIPiDIP-29531N.
IntActiP0ADZ7. 1 interaction.
STRINGi511145.b0407.

Structurei

Secondary structure

1
110
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi22 – 3716Combined sources
Helixi39 – 4911Combined sources
Helixi52 – 543Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2RDDX-ray3.50B19-55[»]
ProteinModelPortaliP0ADZ7.
SMRiP0ADZ7. Positions 19-55.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0ADZ7.

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0092 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105VIE. Bacteria.
COG1862. LUCA.
HOGENOMiHOG000018859.
InParanoidiP0ADZ7.
KOiK03210.
OMAiFFISSAW.
PhylomeDBiP0ADZ7.

Family and domain databases

InterProiIPR003849. Preprotein_translocase_YajC.
[Graphical view]
PfamiPF02699. YajC. 1 hit.
[Graphical view]
PRINTSiPR01853. YAJCTRNLCASE.
SMARTiSM01323. YajC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00739. yajC. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ADZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFFISDAVA ATGAPAQGSP MSLILMLVVF GLIFYFMILR PQQKRTKEHK
60 70 80 90 100
KLMDSIAKGD EVLTNGGLVG RVTKVAENGY IAIALNDTTE VVIKRDFVAA
110
VLPKGTMKAL
Length:110
Mass (Da):11,887
Last modified:December 6, 2005 - v1
Checksum:i8E90AF51F0205306
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti82 – 821A → R in CAA39633 (PubMed:2170107).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56175 Genomic DNA. Translation: CAA39633.1.
M63939 Genomic DNA. Translation: AAA24668.1.
S68715 Genomic DNA. Translation: AAC60468.1.
U82664 Genomic DNA. Translation: AAB40163.1.
U00096 Genomic DNA. Translation: AAC73510.1.
AP009048 Genomic DNA. Translation: BAE76187.1.
PIRiD38530.
RefSeqiNP_414941.1. NC_000913.3.
WP_000007629.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73510; AAC73510; b0407.
BAE76187; BAE76187; BAE76187.
GeneIDi945374.
KEGGiecj:JW0397.
eco:b0407.
PATRICi32115963. VBIEscCol129921_0423.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56175 Genomic DNA. Translation: CAA39633.1.
M63939 Genomic DNA. Translation: AAA24668.1.
S68715 Genomic DNA. Translation: AAC60468.1.
U82664 Genomic DNA. Translation: AAB40163.1.
U00096 Genomic DNA. Translation: AAC73510.1.
AP009048 Genomic DNA. Translation: BAE76187.1.
PIRiD38530.
RefSeqiNP_414941.1. NC_000913.3.
WP_000007629.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2RDDX-ray3.50B19-55[»]
ProteinModelPortaliP0ADZ7.
SMRiP0ADZ7. Positions 19-55.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263532. 351 interactions.
DIPiDIP-29531N.
IntActiP0ADZ7. 1 interaction.
STRINGi511145.b0407.

Protein family/group databases

TCDBi3.A.5.1.1. the general secretory pathway (sec) family.

Proteomic databases

EPDiP0ADZ7.
PaxDbiP0ADZ7.
PRIDEiP0ADZ7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73510; AAC73510; b0407.
BAE76187; BAE76187; BAE76187.
GeneIDi945374.
KEGGiecj:JW0397.
eco:b0407.
PATRICi32115963. VBIEscCol129921_0423.

Organism-specific databases

EchoBASEiEB1088.
EcoGeneiEG11096. yajC.

Phylogenomic databases

eggNOGiENOG4105VIE. Bacteria.
COG1862. LUCA.
HOGENOMiHOG000018859.
InParanoidiP0ADZ7.
KOiK03210.
OMAiFFISSAW.
PhylomeDBiP0ADZ7.

Enzyme and pathway databases

BioCyciEcoCyc:EG11096-MONOMER.
ECOL316407:JW0397-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP0ADZ7.
PROiP0ADZ7.

Family and domain databases

InterProiIPR003849. Preprotein_translocase_YajC.
[Graphical view]
PfamiPF02699. YajC. 1 hit.
[Graphical view]
PRINTSiPR01853. YAJCTRNLCASE.
SMARTiSM01323. YajC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00739. yajC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYAJC_ECOLI
AccessioniPrimary (citable) accession number: P0ADZ7
Secondary accession number(s): P19677, Q2MC19
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: September 7, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.