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Protein

50S ribosomal protein L23

Gene

rplW

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L23UniRule annotation
Gene namesi
Name:rplWUniRule annotation
Ordered Locus Names:Z4689, ECs4183
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001294081 – 10050S ribosomal protein L23Add BLAST100

Proteomic databases

PRIDEiP0ADZ2.

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.UniRule annotation

Protein-protein interaction databases

MINTiMINT-1225801.
STRINGi155864.Z4689.

Structurei

3D structure databases

ProteinModelPortaliP0ADZ2.
SMRiP0ADZ2.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0ADZ2.

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL23 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41080KG. Bacteria.
COG0089. LUCA.
HOGENOMiHOG000231364.
KOiK02892.
OMAiKGIVGRQ.

Family and domain databases

HAMAPiMF_01369_B. Ribosomal_L23_B. 1 hit.
InterProiView protein in InterPro
IPR012678. Ribosomal_L23/L15e_core_dom.
IPR001014. Ribosomal_L23/L25_CS.
IPR013025. Ribosomal_L25/23.
PfamiView protein in Pfam
PF00276. Ribosomal_L23. 1 hit.
SUPFAMiSSF54189. SSF54189. 1 hit.
PROSITEiView protein in PROSITE
PS00050. RIBOSOMAL_L23. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ADZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIREERLLKV LRAPHVSEKA STAMEKSNTI VLKVAKDATK AEIKAAVQKL
60 70 80 90 100
FEVEVEVVNT LVVKGKVKRH GQRIGRRSDW KKAYVTLKEG QNLDFVGGAE
Length:100
Mass (Da):11,199
Last modified:December 6, 2005 - v1
Checksum:i30CD1D77CC7CF9EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG58439.1.
BA000007 Genomic DNA. Translation: BAB37606.1.
PIRiC85997.
G91151.
RefSeqiNP_312210.1. NC_002695.1.
WP_000617544.1. NZ_MKIV01000001.1.

Genome annotation databases

EnsemblBacteriaiAAG58439; AAG58439; Z4689.
BAB37606; BAB37606; BAB37606.
GeneIDi915965.
KEGGiece:Z4689.
ecs:ECs4183.
PATRICi18357914. VBIEscCol44059_4124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG58439.1.
BA000007 Genomic DNA. Translation: BAB37606.1.
PIRiC85997.
G91151.
RefSeqiNP_312210.1. NC_002695.1.
WP_000617544.1. NZ_MKIV01000001.1.

3D structure databases

ProteinModelPortaliP0ADZ2.
SMRiP0ADZ2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1225801.
STRINGi155864.Z4689.

Proteomic databases

PRIDEiP0ADZ2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG58439; AAG58439; Z4689.
BAB37606; BAB37606; BAB37606.
GeneIDi915965.
KEGGiece:Z4689.
ecs:ECs4183.
PATRICi18357914. VBIEscCol44059_4124.

Phylogenomic databases

eggNOGiENOG41080KG. Bacteria.
COG0089. LUCA.
HOGENOMiHOG000231364.
KOiK02892.
OMAiKGIVGRQ.

Miscellaneous databases

EvolutionaryTraceiP0ADZ2.

Family and domain databases

HAMAPiMF_01369_B. Ribosomal_L23_B. 1 hit.
InterProiView protein in InterPro
IPR012678. Ribosomal_L23/L15e_core_dom.
IPR001014. Ribosomal_L23/L25_CS.
IPR013025. Ribosomal_L25/23.
PfamiView protein in Pfam
PF00276. Ribosomal_L23. 1 hit.
SUPFAMiSSF54189. SSF54189. 1 hit.
PROSITEiView protein in PROSITE
PS00050. RIBOSOMAL_L23. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRL23_ECO57
AccessioniPrimary (citable) accession number: P0ADZ2
Secondary accession number(s): P02424
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: December 6, 2005
Last modified: May 10, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.