P0ADY9 (RL16_ECO57) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L16

Gene names

Name:	rplP
Ordered Locus Names:	Z4684, ECs4178

Organism

Escherichia coli O157:H7 [Complete proteome] [HAMAP]

Taxonomic identifier

83334 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	136 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs By similarity. HAMAP MF_01342
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L16P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 136

136

50S ribosomal protein L16 HAMAP MF_01342

PRO_0000062102

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

136

Helix Strand Turn

Details...

Beta strand

8 – 10

3

Helix

44 – 52

9

Beta strand

55 – 57

3

Helix

109 – 117

9

Beta strand

120 – 122

3

Sequences

	Sequence		Length	Mass (Da)
	P0ADY9 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: 445A9B167F7564D1	FASTA	136	15,281
	10 20 30 40 50 60 MLQPKRTKFR KMHKGRNRGL AQGTDVSFGS FGLKAVGRGR LTARQIEAAR RAMTRAVKRQ 70 80 90 100 110 120 GKIWIRVFPD KPITEKPLAV RMGKGKGNVE YWVALIQPGK VLYEMDGVPE ELAREAFKLA 130 AAKLPIKTTF VTKTVM

References

[1]	"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W. , Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R. Nature 409:529-533(2001) [PubMed: 11206551] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
[2]	"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T. , Kuhara S., Shiba T., Hattori M., Shinagawa H. DNA Res. 8:11-22(2001) [PubMed: 11258796] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE005174 Genomic DNA. Translation: AAG58434.1.
BA000007 Genomic DNA. Translation: BAB37601.1.

PIR

B91151.
F85996.

RefSeq

NP_289874.1. NC_002655.2.
NP_312205.1. NC_002695.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3DF2	X-ray	3.50	M	1-136	[»]
3DF4	X-ray	3.50	M	1-136	[»]

ProteinModelPortal

P0ADY9.

SMR

P0ADY9. Positions 1-136.

ModBase

Search...

Proteomic databases

PRIDE

P0ADY9.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBESCT00000026571; EBESCP00000025464; EBESCG00000025624.
EBESCT00000058421; EBESCP00000056249; EBESCG00000057469.

GeneID

915970.
958767.

GenomeReviews

Gene locus Z4684 in contig AE005174_GR.
Gene locus ECs4178 in contig BA000007_GR.

KEGG

ece:Z4684.
ecs:ECs4178.

PATRIC

18357904. VBIEscCol44059_4119.

Organism-specific databases

CMR

Search...

Phylogenomic databases

GeneTree

EBGT00050000009083.

HOGENOM

HBG286097.

OMA

KGSPEFW.

ProtClustDB

PRK09203.

Enzyme and pathway databases

BioCyc

ECOL83334:ECS4178-MONOMER.

Family and domain databases

HAMAP

MF_01342. Ribosomal_L16.
[Tree]

InterPro

IPR016180. Ribosomal_L10e/L16.
IPR000114. Ribosomal_L16.
IPR020798. Ribosomal_L16_CS.
[Graphical view]

KO

K02878.

PANTHER

PTHR12220. Ribosomal_L16. 1 hit.

Pfam

PF00252. Ribosomal_L16. 1 hit.
[Graphical view]

PRINTS

PR00060. RIBOSOMALL16.

SUPFAM

SSF54686. Ribosomal_L10e/L16. 1 hit.

TIGRFAMs

TIGR01164. RplP_bact. 1 hit.

PROSITE

PS00586. RIBOSOMAL_L16_1. 1 hit.
PS00701. RIBOSOMAL_L16_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

RL16_ECO57

Accession

Primary (citable) accession number: P0ADY9
Secondary accession number(s): P02414

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program