ID   LPTC_ECOLI              Reviewed;         191 AA.
AC   P0ADV9; P45397; Q2M913;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   16-JUN-2009, entry version 29.
DE   RecName: Full=Lipopolysaccharide export system protein lptC;
GN   Name=lptC; Synonyms=yrbK; OrderedLocusNames=b3199, JW3166;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   MEDLINE=97426617; PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA   Mau B., Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1474(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains
RT   MG1655 and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 136-191.
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   MEDLINE=95181483; PubMed=7876255; DOI=10.1074/jbc.270.9.4822;
RA   Powell B.S., Court D.L., Inada T., Nakamura Y., Michotey V., Cui X.,
RA   Reizer A., Saier M.H. Jr., Reizer J.;
RT   "Novel proteins of the phosphotransferase system encoded within the
RT   rpoN operon of Escherichia coli. Enzyme IIANtr affects growth on
RT   organic nitrogen and the conditional lethality of an erats mutant.";
RL   J. Biol. Chem. 270:4822-4839(1995).
RN   [4]
RP   FUNCTION IN LIPOPOLYSACCHARIDE TRANSPORT, AND SUBCELLULAR LOCATION.
RC   STRAIN=K12 / MC4100 / ATCC 35695 / DSM 6574;
RX   PubMed=18424520; DOI=10.1128/JB.00270-08;
RA   Sperandeo P., Lau F.K., Carpentieri A., De Castro C., Molinaro A.,
RA   Deho G., Silhavy T.J., Polissi A.;
RT   "Functional analysis of the protein machinery required for transport
RT   of lipopolysaccharide to the outer membrane of Escherichia coli.";
RL   J. Bacteriol. 190:4460-4469(2008).
CC   -!- FUNCTION: Required for the translocation of lipopolysaccharide
CC       (LPS) from the inner membrane to the outer membrane.
CC   -!- INTERACTION:
CC       P18843:nadE; NbExp=1; IntAct=EBI-1131969, EBI-548960;
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the lptC family.
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DR   EMBL; U18997; AAA58001.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76231.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77243.1; -; Genomic_DNA.
DR   EMBL; U12684; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; A65111; A65111.
DR   RefSeq; AP_003742.1; -.
DR   RefSeq; NP_417666.1; -.
DR   IntAct; P0ADV9; 1.
DR   GeneID; 947722; -.
DR   GenomeReviews; AP009048_GR; JW3166.
DR   GenomeReviews; U00096_GR; b3199.
DR   KEGG; ecj:JW3166; -.
DR   KEGG; eco:b3199; -.
DR   EchoBASE; EB2657; -.
DR   EcoGene; EG12806; lptC.
DR   HOGENOM; P0ADV9; -.
DR   OMA; P0ADV9; VQGRYET.
DR   BioCyc; EcoCyc:G7664-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   InterPro; IPR010664; DUF1239.
DR   Pfam; PF06835; DUF1239; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Transmembrane.
FT   CHAIN         1    191       Lipopolysaccharide export system protein
FT                                lptC.
FT                                /FTId=PRO_0000169470.
FT   TRANSMEM      7     25       Potential.
SQ   SEQUENCE   191 AA;  21703 MW;  F6BAE79EA232CD95 CRC64;
     MSKARRWVII VLSLAVLVMI GINMAEKDDT AQVVVNNNDP TYKSEHTDTL VYNPEGALSY
     RLIAQHVEYY SDQAVSWFTQ PVLTTFDKDK IPTWSVKADK AKLTNDRMLY LYGHVEVNAL
     VPDSQLRRIT TDNAQINLVT QDVTSEDLVT LYGTTFNSSG LKMRGNLRSK NAELIEKVRT
     SYEIQNKQTQ P
//