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Protein

Probable quinol monooxygenase YgiN

Gene

ygiN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Can oxidize menadiol to menadione.1 Publication

GO - Molecular functioni

  • oxidoreductase activity Source: EcoCyc

GO - Biological processi

  • response to acidic pH Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:EG12657-MONOMER.
ECOL316407:JW2997-MONOMER.
MetaCyc:EG12657-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable quinol monooxygenase YgiN (EC:1.-.-.-)
Short name:
QuMo
Gene namesi
Name:ygiN
Ordered Locus Names:b3029, JW2997
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12657. ygiN.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 104104Probable quinol monooxygenase YgiNPRO_0000169408Add
BLAST

Proteomic databases

EPDiP0ADU2.
PaxDbiP0ADU2.
PRIDEiP0ADU2.

2D gel databases

SWISS-2DPAGEP0ADU2.

Interactioni

Subunit structurei

Homodimer.1 Publication

Protein-protein interaction databases

BioGridi4262392. 5 interactions.
IntActiP0ADU2. 2 interactions.
STRINGi511145.b3029.

Structurei

Secondary structure

1
104
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi2 – 109Combined sources
Beta strandi12 – 154Combined sources
Helixi16 – 3318Combined sources
Beta strandi37 – 437Combined sources
Beta strandi59 – 679Combined sources
Helixi69 – 768Combined sources
Helixi79 – 8810Combined sources
Turni89 – 913Combined sources
Beta strandi92 – 1009Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1R6YX-ray2.20A1-104[»]
1TUVX-ray1.70A1-104[»]
ProteinModelPortaliP0ADU2.
SMRiP0ADU2. Positions 1-103.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0ADU2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 10099ABMAdd
BLAST

Sequence similaritiesi

Contains 1 ABM domain.Curated

Phylogenomic databases

eggNOGiENOG4105VRH. Bacteria.
COG1359. LUCA.
HOGENOMiHOG000145619.
InParanoidiP0ADU2.
OMAiVLQEEGC.
OrthoDBiEOG6FFSBV.

Family and domain databases

InterProiIPR007138. ABM_dom.
IPR011008. Dimeric_a/b-barrel.
[Graphical view]
PfamiPF03992. ABM. 1 hit.
[Graphical view]
SUPFAMiSSF54909. SSF54909. 1 hit.
PROSITEiPS51725. ABM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ADU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTVIAEIRT RPGQHHRQAV LDQFAKIVPT VLKEEGCHGY APMVDCAAGV
60 70 80 90 100
SFQSMAPDSI VMIEQWESIA HLEAHLQTPH MKAYSEAVKG DVLEMNIRIL

QPGI
Length:104
Mass (Da):11,532
Last modified:December 6, 2005 - v1
Checksum:i46E7B5A11ADED1EA
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti4 – 41Missing AA sequence (PubMed:9868784).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18656 Genomic DNA. No translation available.
U28377 Genomic DNA. Translation: AAA69197.1.
U00096 Genomic DNA. Translation: AAC76065.1.
AP009048 Genomic DNA. Translation: BAE77085.1.
PIRiC65090.
RefSeqiNP_417501.1. NC_000913.3.
WP_000958598.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76065; AAC76065; b3029.
BAE77085; BAE77085; BAE77085.
GeneIDi947506.
KEGGiecj:JW2997.
eco:b3029.
PATRICi32121468. VBIEscCol129921_3121.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18656 Genomic DNA. No translation available.
U28377 Genomic DNA. Translation: AAA69197.1.
U00096 Genomic DNA. Translation: AAC76065.1.
AP009048 Genomic DNA. Translation: BAE77085.1.
PIRiC65090.
RefSeqiNP_417501.1. NC_000913.3.
WP_000958598.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1R6YX-ray2.20A1-104[»]
1TUVX-ray1.70A1-104[»]
ProteinModelPortaliP0ADU2.
SMRiP0ADU2. Positions 1-103.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262392. 5 interactions.
IntActiP0ADU2. 2 interactions.
STRINGi511145.b3029.

2D gel databases

SWISS-2DPAGEP0ADU2.

Proteomic databases

EPDiP0ADU2.
PaxDbiP0ADU2.
PRIDEiP0ADU2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76065; AAC76065; b3029.
BAE77085; BAE77085; BAE77085.
GeneIDi947506.
KEGGiecj:JW2997.
eco:b3029.
PATRICi32121468. VBIEscCol129921_3121.

Organism-specific databases

EchoBASEiEB2525.
EcoGeneiEG12657. ygiN.

Phylogenomic databases

eggNOGiENOG4105VRH. Bacteria.
COG1359. LUCA.
HOGENOMiHOG000145619.
InParanoidiP0ADU2.
OMAiVLQEEGC.
OrthoDBiEOG6FFSBV.

Enzyme and pathway databases

BioCyciEcoCyc:EG12657-MONOMER.
ECOL316407:JW2997-MONOMER.
MetaCyc:EG12657-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP0ADU2.
PROiP0ADU2.

Family and domain databases

InterProiIPR007138. ABM_dom.
IPR011008. Dimeric_a/b-barrel.
[Graphical view]
PfamiPF03992. ABM. 1 hit.
[Graphical view]
SUPFAMiSSF54909. SSF54909. 1 hit.
PROSITEiPS51725. ABM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A general genetic approach in Escherichia coli for determining the mechanism(s) of action of tumoricidal agents: application to DMP 840, a tumoricidal agent."
    Chatterjee P.K., Sternberg N.L.
    Proc. Natl. Acad. Sci. U.S.A. 92:8950-8954(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Small genes/gene-products in Escherichia coli K-12."
    Wasinger V.C., Humphery-Smith I.
    FEMS Microbiol. Lett. 169:375-382(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-20.
    Strain: K12.
  5. "Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12."
    Link A.J., Robison K., Church G.M.
    Electrophoresis 18:1259-1313(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-12.
    Strain: K12 / EMG2.
  6. Cited for: PROTEIN SEQUENCE OF 1-4.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  7. "Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite chromatography."
    Fountoulakis M., Takacs M.-F., Berndt P., Langen H., Takacs B.
    Electrophoresis 20:2181-2195(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: B / BL21.
  8. "Structural and biochemical evidence for an enzymatic quinone redox cycle in Escherichia coli: identification of a novel quinol monooxygenase."
    Adams M.A., Jia Z.
    J. Biol. Chem. 280:8358-8363(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) IN COMPLEX WITH MENADIONE, FUNCTION, SUBUNIT.

Entry informationi

Entry nameiYGIN_ECOLI
AccessioniPrimary (citable) accession number: P0ADU2
Secondary accession number(s): P40718, Q2M9H1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: March 16, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.