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Protein

Ubiquinone biosynthesis protein UbiJ

Gene

ubiJ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in ubiquinone (coenzyme Q) biosynthesis under aerobic conditions.1 Publication

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.1 Publication
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

GO - Biological processi

  • ubiquinone biosynthetic process from chorismate Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Ubiquinone biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11474-MONOMER.
ECOL316407:JW3811-MONOMER.
UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquinone biosynthesis protein UbiJCurated
Gene namesi
Name:ubiJ1 Publication
Synonyms:yigP
Ordered Locus Names:b3834, JW3811
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11474. ubiJ.

Pathology & Biotechi

Disruption phenotypei

During aerobic growth, mutant is impaired for ubiquinone biosynthesis and for growth in rich medium, but it does not present any defect under anaerobic conditions.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 201201Ubiquinone biosynthesis protein UbiJPRO_0000169668Add
BLAST

Proteomic databases

PaxDbiP0ADP7.

Interactioni

Protein-protein interaction databases

IntActiP0ADP7. 1 interaction.
STRINGi511145.b3834.

Structurei

3D structure databases

ProteinModelPortaliP0ADP7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UbiJ family.Curated

Phylogenomic databases

eggNOGiENOG4105JC1. Bacteria.
COG3165. LUCA.
HOGENOMiHOG000269583.
KOiK03690.
OMAiAPYIGDI.
OrthoDBiEOG6GR387.

Family and domain databases

InterProiIPR003033. SCP2_sterol-bd_dom.
[Graphical view]
PfamiPF02036. SCP2. 1 hit.
[Graphical view]
SUPFAMiSSF55718. SSF55718. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ADP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFKPLVTAG IESLLNTFLY RSPALKTARS RLLGKVLRVE VKGFSTSLIL
60 70 80 90 100
VFSERQVDVL GEWAGDADCT VIAYASVLPK LRDRQQLTAL IRSGELEVQG
110 120 130 140 150
DIQVVQNFVA LADLAEFDPA ELLAPYTGDI AAEGISKAMR GGAKFLHHGI
160 170 180 190 200
KRQQRYVAEA ITEEWRMAPG PLEVAWFAEE TAAVERAVDA LTKRLEKLEA

K
Length:201
Mass (Da):22,153
Last modified:December 6, 2005 - v1
Checksum:i9C64980A59992A2E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti119 – 13921PAELL…ISKAM → LRNCWPLIPVISPLKESAKP in AAA67629 (PubMed:1379743).CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M87049 Genomic DNA. Translation: AAA67629.1.
U00096 Genomic DNA. Translation: AAC76837.1.
AP009048 Genomic DNA. Translation: BAE77467.1.
PIRiC65188.
RefSeqiNP_418278.1. NC_000913.3.
WP_001295259.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76837; AAC76837; b3834.
BAE77467; BAE77467; BAE77467.
GeneIDi948915.
KEGGiecj:JW3811.
eco:b3834.
PATRICi32123169. VBIEscCol129921_3950.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M87049 Genomic DNA. Translation: AAA67629.1.
U00096 Genomic DNA. Translation: AAC76837.1.
AP009048 Genomic DNA. Translation: BAE77467.1.
PIRiC65188.
RefSeqiNP_418278.1. NC_000913.3.
WP_001295259.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0ADP7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP0ADP7. 1 interaction.
STRINGi511145.b3834.

Proteomic databases

PaxDbiP0ADP7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76837; AAC76837; b3834.
BAE77467; BAE77467; BAE77467.
GeneIDi948915.
KEGGiecj:JW3811.
eco:b3834.
PATRICi32123169. VBIEscCol129921_3950.

Organism-specific databases

EchoBASEiEB1442.
EcoGeneiEG11474. ubiJ.

Phylogenomic databases

eggNOGiENOG4105JC1. Bacteria.
COG3165. LUCA.
HOGENOMiHOG000269583.
KOiK03690.
OMAiAPYIGDI.
OrthoDBiEOG6GR387.

Enzyme and pathway databases

UniPathwayiUPA00232.
BioCyciEcoCyc:EG11474-MONOMER.
ECOL316407:JW3811-MONOMER.

Miscellaneous databases

PROiP0ADP7.

Family and domain databases

InterProiIPR003033. SCP2_sterol-bd_dom.
[Graphical view]
PfamiPF02036. SCP2. 1 hit.
[Graphical view]
SUPFAMiSSF55718. SSF55718. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes."
    Daniels D.L., Plunkett G. III, Burland V.D., Blattner F.R.
    Science 257:771-778(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION TO 119-139.
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "ubiJ, a new gene required for aerobic growth and proliferation in macrophage, is involved in coenzyme Q biosynthesis in Escherichia coli and Salmonella enterica serovar Typhimurium."
    Aussel L., Loiseau L., Hajj Chehade M., Pocachard B., Fontecave M., Pierrel F., Barras F.
    J. Bacteriol. 196:70-79(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, PATHWAY, DISRUPTION PHENOTYPE.
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiUBIJ_ECOLI
AccessioniPrimary (citable) accession number: P0ADP7
Secondary accession number(s): P27852, Q2M8D9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: November 11, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.