P0ADM0 (YIDH_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Inner membrane protein YidH

Gene names

Name:	yidH
Ordered Locus Names:	b3676, JW3652

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	115 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cell inner membrane; Multi-pass membrane protein.
Sequence similarities	To M.tuberculosis Rv2272.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 115	115	Inner membrane protein YidH		PRO_0000169628
Regions
	Topological domain	1 – 30	30	Cytoplasmic Potential
	Transmembrane	31 – 51	21	Helical; Potential
	Topological domain	52 – 53	2	Periplasmic Potential
	Transmembrane	54 – 74	21	Helical; Potential
	Topological domain	75 – 92	18	Cytoplasmic Potential
	Transmembrane	93 – 113	21	Helical; Potential
	Topological domain	114 – 115	2	Periplasmic Potential

Sequences

	Sequence		Length	Mass (Da)
	P0ADM0 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 59E08E0F3EA7125A	FASTA	115	12,779
	10 20 30 40 50 60 MKISRLGEAP DYRFSLANER TFLAWIRTAL GFLAAGVGLD QLAPDFATPV IRELLALLLC 70 80 90 100 110 LFSGGLAMYG YLRWLRNEKA MRLKEDLPYT NSLLIISLIL MVVAVIVMGL VLYAG

References

[1]	"DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication." Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R. Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Global topology analysis of the Escherichia coli inner membrane proteome." Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G. Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. Strain: K12 / MG1655 / ATCC 47076.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L10328 Genomic DNA. Translation: AAA62028.1. U00096 Genomic DNA. Translation: AAC76699.1. AP009048 Genomic DNA. Translation: BAE77617.1.
PIR	E65169.
RefSeq	NP_418132.1. NC_000913.2. YP_491758.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P0ADM0.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-47894N.
STRING	511145.b3676.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC76699; AAC76699; b3676. BAE77617; BAE77617; BAE77617.
GeneID	12933593. 948190.
KEGG	ecj:Y75_p3498. eco:b3676.
PATRIC	32122843. VBIEscCol129921_3797.
Organism-specific databases
EchoBASE	EB1647.
EcoGene	EG11696. yidH.
Phylogenomic databases
eggNOG	COG2149.
HOGENOM	HOG000236086.
KO	K00389.
OMA	CERAMRR.
ProtClustDB	CLSK880763.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11696-MONOMER. ECOL316407:JW3652-MONOMER.
Gene expression databases
Genevestigator	P0ADM0.
Family and domain databases
InterPro	IPR003807. DUF202. [Graphical view]
Pfam	PF02656. DUF202. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YIDH_ECOLI

Accession

Primary (citable) accession number: P0ADM0
Secondary accession number(s): P31445, Q2M7Y9

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program