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Protein

Cellulose biosynthesis protein BcsF

Gene

bcsF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Miscellaneous

Cellulose production is abolished in E.coli K12 / MG1655 and W3110 due to a premature stop codon in bcsQ (PubMed:24097954).1 Publication

GO - Biological processi

Keywordsi

Biological processCellulose biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG12264-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cellulose biosynthesis protein BcsF
Gene namesi
Name:bcsF
Synonyms:yhjT
Ordered Locus Names:b3537, JW5663
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12264 bcsF

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

When the bcsEFG operon is disrupted in a cellulose-synthesizing strain (a strain K12 / W3110 derivative called AR3110 with a restored, functional bcsQ gene), cellulose is no longer made.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001695811 – 63Cellulose biosynthesis protein BcsFAdd BLAST63

Proteomic databases

PaxDbiP0ADJ5
PRIDEiP0ADJ5

Interactioni

Protein-protein interaction databases

BioGridi4260851, 219 interactors

Structurei

3D structure databases

ProteinModelPortaliP0ADJ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BcsF family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105WQA Bacteria
ENOG41123GA LUCA
HOGENOMiHOG000268034
OMAiVFCALIF

Family and domain databases

InterProiView protein in InterPro
IPR019995 Cellulose_BcsF/YhjT
PfamiView protein in Pfam
PF11120 CBP_BcsF, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD053231 Cellulose_BcsF/YhjT, 1 hit
TIGRFAMsiTIGR03493 cellullose_BcsF, 1 hit

Sequencei

Sequence statusi: Complete.

P0ADJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTISDIIEI IVVCALIFFP LGYLARHSLR RIRDTLRLFF AKPRYVKPAG
60
TLRRTEKARA TKK
Length:63
Mass (Da):7,364
Last modified:June 27, 2006 - v2
Checksum:i7CA2611DCE4CA155
GO

Sequence cautioni

The sequence AAB18515 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA Translation: AAB18515.1 Different initiation.
U00096 Genomic DNA Translation: AAC76562.2
AP009048 Genomic DNA Translation: BAE77758.1
PIRiS47759
RefSeqiNP_417994.2, NC_000913.3
WP_000988308.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76562; AAC76562; b3537
BAE77758; BAE77758; BAE77758
GeneIDi948059
KEGGiecj:JW5663
eco:b3537
PATRICifig|511145.12.peg.3648

Similar proteinsi

Entry informationi

Entry nameiBCSF_ECOLI
AccessioniPrimary (citable) accession number: P0ADJ5
Secondary accession number(s): P37658, Q2M7J8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: June 27, 2006
Last modified: March 28, 2018
This is version 78 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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