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Protein

Isochorismatase family protein YecD

Gene

yecD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. hydrolase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciEcoCyc:EG12378-MONOMER.
ECOL316407:JW5307-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isochorismatase family protein YecD (EC:3.-.-.-)
Gene namesi
Name:yecD
Ordered Locus Names:b1867, JW5307
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318 Componenti: Chromosome UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12378. yecD.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 188188Isochorismatase family protein YecDPRO_0000201831Add
BLAST

Proteomic databases

PaxDbiP0ADI7.

Expressioni

Gene expression databases

GenevestigatoriP0ADI7.

Interactioni

Protein-protein interaction databases

STRINGi511145.b1867.

Structurei

Secondary structure

1
188
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 83Combined sources
Beta strandi9 – 146Combined sources
Turni18 – 203Combined sources
Helixi21 – 233Combined sources
Beta strandi26 – 283Combined sources
Helixi30 – 4617Combined sources
Beta strandi51 – 566Combined sources
Turni81 – 844Combined sources
Helixi88 – 903Combined sources
Beta strandi96 – 10712Combined sources
Helixi112 – 1187Combined sources
Beta strandi123 – 1297Combined sources
Turni131 – 1333Combined sources
Helixi134 – 14411Combined sources
Beta strandi148 – 16013Combined sources
Helixi161 – 17010Combined sources
Helixi172 – 1754Combined sources
Beta strandi176 – 1794Combined sources
Helixi181 – 1877Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1J2RX-ray1.30A/B/C/D1-188[»]
ProteinModelPortaliP0ADI7.
SMRiP0ADI7. Positions 1-188.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0ADI7.

Family & Domainsi

Sequence similaritiesi

Belongs to the isochorismatase family.Curated

Phylogenomic databases

eggNOGiCOG1335.
HOGENOMiHOG000078668.
InParanoidiP0ADI7.
OMAiAAKFRAN.
OrthoDBiEOG6MM1KP.
PhylomeDBiP0ADI7.

Family and domain databases

Gene3Di3.40.50.850. 1 hit.
InterProiIPR000868. Isochorismatase-like.
[Graphical view]
PfamiPF00857. Isochorismatase. 1 hit.
[Graphical view]
SUPFAMiSSF52499. SSF52499. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ADI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLELNAKTTA LVVIDLQEGI LPFAGGPHTA DEVVNRAGKL AAKFRASGQP
60 70 80 90 100
VFLVRVGWSA DYAEALKQPV DAPSPAKVLP ENWWQHPAAL GATDSDIEII
110 120 130 140 150
KRQWGAFYGT DLELQLRRRG IDTIVLCGIS TNIGVESTAR NAWELGFNLV
160 170 180
IAEDACSAAS AEQHNNSINH IYPRIARVRS VEEILNAL
Length:188
Mass (Da):20,452
Last modified:January 14, 2008 - v2
Checksum:i3850DE203370249E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti180 – 1889SVEEILNAL → TWKRSSTRYDLHRSTAMVAS (PubMed:2129559).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53863 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC74937.2.
AP009048 Genomic DNA. Translation: BAA15678.1.
PIRiC64949.
RefSeqiNP_416381.2. NC_000913.3.
YP_490129.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC74937; AAC74937; b1867.
BAA15678; BAA15678; BAA15678.
GeneIDi12930338.
946384.
KEGGiecj:Y75_p1843.
eco:b1867.
PATRICi32119057. VBIEscCol129921_1946.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53863 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC74937.2.
AP009048 Genomic DNA. Translation: BAA15678.1.
PIRiC64949.
RefSeqiNP_416381.2. NC_000913.3.
YP_490129.1. NC_007779.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1J2RX-ray1.30A/B/C/D1-188[»]
ProteinModelPortaliP0ADI7.
SMRiP0ADI7. Positions 1-188.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi511145.b1867.

Proteomic databases

PaxDbiP0ADI7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74937; AAC74937; b1867.
BAA15678; BAA15678; BAA15678.
GeneIDi12930338.
946384.
KEGGiecj:Y75_p1843.
eco:b1867.
PATRICi32119057. VBIEscCol129921_1946.

Organism-specific databases

EchoBASEiEB2280.
EcoGeneiEG12378. yecD.

Phylogenomic databases

eggNOGiCOG1335.
HOGENOMiHOG000078668.
InParanoidiP0ADI7.
OMAiAAKFRAN.
OrthoDBiEOG6MM1KP.
PhylomeDBiP0ADI7.

Enzyme and pathway databases

BioCyciEcoCyc:EG12378-MONOMER.
ECOL316407:JW5307-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP0ADI7.
PROiP0ADI7.

Gene expression databases

GenevestigatoriP0ADI7.

Family and domain databases

Gene3Di3.40.50.850. 1 hit.
InterProiIPR000868. Isochorismatase-like.
[Graphical view]
PfamiPF00857. Isochorismatase. 1 hit.
[Graphical view]
SUPFAMiSSF52499. SSF52499. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Aspartyl-tRNA synthetase from Escherichia coli: cloning and characterisation of the gene, homologies of its translated amino acid sequence with asparaginyl- and lysyl-tRNA synthetases."
    Eriani G., Dirheimer G., Gangloff J.
    Nucleic Acids Res. 18:7109-7118(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Intrinsic and extrinsic approaches for detecting genes in a bacterial genome."
    Borodovsky M., Rudd K.E., Koonin E.V.
    Nucleic Acids Res. 22:4756-4767(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.
  6. Cited for: X-RAY CRYSTALLOGRAPHY (1.3 ANGSTROMS).

Entry informationi

Entry nameiYECD_ECOLI
AccessioniPrimary (citable) accession number: P0ADI7
Secondary accession number(s): P37347, P76287
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 5, 2005
Last sequence update: January 14, 2008
Last modified: January 6, 2015
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.