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P0ADI7 (YECD_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Isochorismatase family protein YecD

EC=3.-.-.-
Gene names
Name:yecD
Ordered Locus Names:b1867, JW5307
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length188 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the isochorismatase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionhydrolase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 188188Isochorismatase family protein YecD
PRO_0000201831

Experimental info

Sequence conflict180 – 1889SVEEILNAL → TWKRSSTRYDLHRSTAMVAS Ref.1

Secondary structure

.................................. 188
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P0ADI7 [UniParc].

Last modified January 15, 2008. Version 2.
Checksum: 3850DE203370249E

FASTA18820,452
        10         20         30         40         50         60 
MLELNAKTTA LVVIDLQEGI LPFAGGPHTA DEVVNRAGKL AAKFRASGQP VFLVRVGWSA 

        70         80         90        100        110        120 
DYAEALKQPV DAPSPAKVLP ENWWQHPAAL GATDSDIEII KRQWGAFYGT DLELQLRRRG 

       130        140        150        160        170        180 
IDTIVLCGIS TNIGVESTAR NAWELGFNLV IAEDACSAAS AEQHNNSINH IYPRIARVRS 


VEEILNAL 

« Hide

References

« Hide 'large scale' references
[1]"Aspartyl-tRNA synthetase from Escherichia coli: cloning and characterisation of the gene, homologies of its translated amino acid sequence with asparaginyl- and lysyl-tRNA synthetases."
Eriani G., Dirheimer G., Gangloff J.
Nucleic Acids Res. 18:7109-7118(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: K12.
[2]"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map."
Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. expand/collapse author list , Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:379-392(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]"Intrinsic and extrinsic approaches for detecting genes in a bacterial genome."
Borodovsky M., Rudd K.E., Koonin E.V.
Nucleic Acids Res. 22:4756-4767(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.
[6]"Structural genomics of highly conserved microbial genes of unknown function in search of new antibacterial targets."
Abergel C., Coutard B., Byrne D., Chenivesse S., Claude J.-B., Deregnaucourt C., Fricaux T., Gianesini-Boutreux C., Jeudy S., Lebrun R., Maza C., Notredame C., Poirot O., Suhre K., Varagnol M., Claverie J.-M.
J. Struct. Funct. Genomics 4:141-157(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.3 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X53863 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC74937.2.
AP009048 Genomic DNA. Translation: BAA15678.1.
PIRC64949.
RefSeqNP_416381.2. NC_000913.3.
YP_490129.1. NC_007779.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1J2RX-ray1.30A/B/C/D1-188[»]
ProteinModelPortalP0ADI7.
SMRP0ADI7. Positions 1-188.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING511145.b1867.

Proteomic databases

PaxDbP0ADI7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC74937; AAC74937; b1867.
BAA15678; BAA15678; BAA15678.
GeneID12930338.
946384.
KEGGecj:Y75_p1843.
eco:b1867.
PATRIC32119057. VBIEscCol129921_1946.

Organism-specific databases

EchoBASEEB2280.
EcoGeneEG12378. yecD.

Phylogenomic databases

eggNOGCOG1335.
HOGENOMHOG000078668.
OMAFSLVIAE.
OrthoDBEOG6MM1KP.
PhylomeDBP0ADI7.

Enzyme and pathway databases

BioCycEcoCyc:EG12378-MONOMER.
ECOL316407:JW5307-MONOMER.

Gene expression databases

GenevestigatorP0ADI7.

Family and domain databases

Gene3D3.40.50.850. 1 hit.
InterProIPR000868. Isochorismatase-like.
[Graphical view]
PfamPF00857. Isochorismatase. 1 hit.
[Graphical view]
SUPFAMSSF52499. SSF52499. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP0ADI7.
PROP0ADI7.

Entry information

Entry nameYECD_ECOLI
AccessionPrimary (citable) accession number: P0ADI7
Secondary accession number(s): P37347, P76287
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene