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Protein

Serine recombinase PinR

Gene

pinR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei11O-(5'-phospho-DNA)-serine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DNA invertase, Hydrolase, Ligase

Keywords - Biological processi

DNA integration, DNA recombination

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6697-MONOMER.
ECOL316407:JW1368-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine recombinase PinRBy similarity (EC:3.1.22.-, EC:6.5.1.-)
Alternative name(s):
DNA-invertase PinRCurated
Putative DNA-invertase from lambdoid prophage Rac
Site-specific recombinase PinRCurated
Gene namesi
Name:pinR
Synonyms:ynaD
Ordered Locus Names:b1374, JW1368
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13372. pinR.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001963631 – 196Serine recombinase PinRAdd BLAST196

Proteomic databases

PaxDbiP0ADI0.
PRIDEiP0ADI0.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
aceFP069592EBI-544672,EBI-542707

Protein-protein interaction databases

BioGridi4263521. 165 interactors.
DIPiDIP-47969N.
IntActiP0ADI0. 9 interactors.
STRINGi511145.b1374.

Structurei

3D structure databases

ProteinModelPortaliP0ADI0.
SMRiP0ADI0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 143Resolvase/invertase-type recombinase catalyticPROSITE-ProRule annotationAdd BLAST141

Sequence similaritiesi

Contains 1 resolvase/invertase-type recombinase catalytic domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105MN3. Bacteria.
COG1961. LUCA.
HOGENOMiHOG000275578.
InParanoidiP0ADI0.
KOiK14060.
OMAiWFADIVS.
PhylomeDBiP0ADI0.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
3.40.50.1390. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR006118. Recombinase_CS.
IPR006119. Resolv_N.
IPR006120. Resolvase_HTH_dom.
[Graphical view]
PfamiPF02796. HTH_7. 1 hit.
PF00239. Resolvase. 1 hit.
[Graphical view]
SMARTiSM00857. Resolvase. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF53041. SSF53041. 1 hit.
PROSITEiPS00398. RECOMBINASES_2. 1 hit.
PS51736. RECOMBINASES_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ADI0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRIFAYCRI STLDQTTENQ RREIESAGFK IKPQQIIEEH ISGSAATSER
60 70 80 90 100
PGFNRLLARL KCGDQLIVTK LDRLGCNAMD IRKTVEQLTE TGIRVHCLAL
110 120 130 140 150
GGIDLTSPTG KMMMQVISAV AEFERDLLLE RTHSGIVRAR GAGKRFGRPP
160 170 180 190
VLNEEQKQVV FERIKSGVSI SAIAREFKTS RQTILRAKAK LQTPDI
Length:196
Mass (Da):21,908
Last modified:December 6, 2005 - v1
Checksum:i643A62BC940B29A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74456.1.
AP009048 Genomic DNA. Translation: BAA14979.1.
PIRiA64888.
RefSeqiNP_415892.1. NC_000913.3.
WP_000086527.1. NZ_CP014272.1.

Genome annotation databases

EnsemblBacteriaiAAC74456; AAC74456; b1374.
BAA14979; BAA14979; BAA14979.
GeneIDi948973.
KEGGiecj:JW1368.
eco:b1374.
PATRICi32118030. VBIEscCol129921_1435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74456.1.
AP009048 Genomic DNA. Translation: BAA14979.1.
PIRiA64888.
RefSeqiNP_415892.1. NC_000913.3.
WP_000086527.1. NZ_CP014272.1.

3D structure databases

ProteinModelPortaliP0ADI0.
SMRiP0ADI0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263521. 165 interactors.
DIPiDIP-47969N.
IntActiP0ADI0. 9 interactors.
STRINGi511145.b1374.

Proteomic databases

PaxDbiP0ADI0.
PRIDEiP0ADI0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74456; AAC74456; b1374.
BAA14979; BAA14979; BAA14979.
GeneIDi948973.
KEGGiecj:JW1368.
eco:b1374.
PATRICi32118030. VBIEscCol129921_1435.

Organism-specific databases

EchoBASEiEB3154.
EcoGeneiEG13372. pinR.

Phylogenomic databases

eggNOGiENOG4105MN3. Bacteria.
COG1961. LUCA.
HOGENOMiHOG000275578.
InParanoidiP0ADI0.
KOiK14060.
OMAiWFADIVS.
PhylomeDBiP0ADI0.

Enzyme and pathway databases

BioCyciEcoCyc:G6697-MONOMER.
ECOL316407:JW1368-MONOMER.

Miscellaneous databases

PROiP0ADI0.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
3.40.50.1390. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR006118. Recombinase_CS.
IPR006119. Resolv_N.
IPR006120. Resolvase_HTH_dom.
[Graphical view]
PfamiPF02796. HTH_7. 1 hit.
PF00239. Resolvase. 1 hit.
[Graphical view]
SMARTiSM00857. Resolvase. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF53041. SSF53041. 1 hit.
PROSITEiPS00398. RECOMBINASES_2. 1 hit.
PS51736. RECOMBINASES_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPINR_ECOLI
AccessioniPrimary (citable) accession number: P0ADI0
Secondary accession number(s): P77574
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: November 30, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.