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Reviewed, UniProtKB/Swiss-Prot P0ADG5 (SUHB_ECOL6)

Last modified June 16, 2009. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Inositol-1-monophosphatase
      Short name=IMPase
      Short name=Inositol-1-phosphatase
      Short name=I-1-Pase
    EC=3.1.3.25
Gene names
Name: suhB
Ordered Locus Names: c3059
OrganismEscherichia coli O6 [Complete proteome] [HAMAP]
Taxonomic identifier217992 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

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Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Myo-inositol phosphate + H2O = myo-inositol + phosphate.

Cofactor

Magnesium By similarity.

Subunit structure

Monomer By similarity.

Sequence similarities

Belongs to the inositol monophosphatase family.

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Ontologies

Keywords
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioninositol-1(or 4)-monophosphatase activity

Inferred from electronic annotation. Source: EC

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Inositol-1-monophosphatase
PRO_0000142561

Sites

Metal binding671Magnesium 1 By similarity
Metal binding841Magnesium 1 By similarity
Metal binding841Magnesium 2 By similarity
Metal binding861Magnesium 1; via carbonyl oxygen By similarity
Metal binding871Magnesium 2 By similarity
Metal binding2121Magnesium 2 By similarity
Binding site871Substrate By similarity
Binding site1831Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
P0ADG5-1 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 8FEC3508BD111301

FASTA26729,172
        10         20         30         40         50         60 
MHPMLNIAVR AARKAGNLIA KNYETPDAVE ASQKGSNDFV TNVDKAAEAV IIDTIRKSYP 

        70         80         90        100        110        120 
QHTIITEESG ELEGTDQDVQ WVIDPLDGTT NFIKRLPHFA VSIAVRIKGR TEVAVVYDPM 

       130        140        150        160        170        180 
RNELFTATRG QGAQLNGYRL RGSTARDLDG TILATGFPFK AKQYATTYIN IVGKLFNECA 

       190        200        210        220        230        240 
DFRRTGSAAL DLAYVAAGRV DGFFEIGLRP WDFAAGELLV REAGGIVSDF TGGHNYMLTG 

       250        260 
NIVAGNPRVV KAMLANMRDE LSDALKR

« Hide

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References

[1]"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli."
Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R.
Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed: 12471157] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O6:H1 / CFT073 / ATCC 700928 / UPEC.

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Cross-references

Sequence databases

AE014075 Genomic DNA. Translation: AAN81509.1.
RefSeqNP_754941.1.

3D structure databases

HSSPHSSP built from PDB template 1IMF based on UniProtKB P29218.
ModBaseSearch...

Genome annotation databases

GeneID1038758.
GenomeReviewsGene locus c3059 in contig AE014075_GR.
KEGGecc:c3059.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP0ADG5.
OMAP0ADG5. KGINDYV.

Enzyme and pathway databases

BRENDA3.1.3.25. 292881.

Family and domain databases

InterProIPR000760. Inositol_P.
[Graphical view]
PANTHERPTHR20854. Inositol_P. 1 hit.
PfamPF00459. Inositol_P. 1 hit.
[Graphical view]
PRINTSPR00378. INOSPHPHTASE.
ProDomPD023420. Inositol_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEPS00629. IMP_1. 1 hit.
PS00630. IMP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameSUHB_ECOL6
AccessionPrimary (citable) accession number: P0ADG5
Secondary accession number(s): P22783, P77511, Q8X2E6
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents