Skip Header

Contribute Send feedback
Read comments (?) or add your own

P0ADG5 (SUHB_ECOL6) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Inositol-1-monophosphatase
Short name=I-1-Pase
Short name=IMPase
Short name=Inositol-1-phosphatase
EC=3.1.3.25
Gene names
Name:suhB
Ordered Locus Names:c3059
OrganismEscherichia coli O6 [Complete proteome] [HAMAP]
Taxonomic identifier217992 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Myo-inositol phosphate + H2O = myo-inositol + phosphate.

Cofactor

Magnesium By similarity.

Subunit structure

Monomer By similarity.

Sequence similarities

Belongs to the inositol monophosphatase family.

Ontologies

Keywords
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioninositol monophosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Inositol-1-monophosphatase
PRO_0000142561

Regions

Region86 – 894Substrate binding By similarity

Sites

Metal binding671Magnesium 1 By similarity
Metal binding841Magnesium 1 By similarity
Metal binding841Magnesium 2 By similarity
Metal binding861Magnesium 1; via carbonyl oxygen By similarity
Metal binding871Magnesium 2 By similarity
Metal binding2121Magnesium 2 By similarity
Binding site671Substrate By similarity
Binding site1831Substrate By similarity
Binding site2121Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
P0ADG5 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 8FEC3508BD111301

FASTA26729,172
        10         20         30         40         50         60 
MHPMLNIAVR AARKAGNLIA KNYETPDAVE ASQKGSNDFV TNVDKAAEAV IIDTIRKSYP 

        70         80         90        100        110        120 
QHTIITEESG ELEGTDQDVQ WVIDPLDGTT NFIKRLPHFA VSIAVRIKGR TEVAVVYDPM 

       130        140        150        160        170        180 
RNELFTATRG QGAQLNGYRL RGSTARDLDG TILATGFPFK AKQYATTYIN IVGKLFNECA 

       190        200        210        220        230        240 
DFRRTGSAAL DLAYVAAGRV DGFFEIGLRP WDFAAGELLV REAGGIVSDF TGGHNYMLTG 

       250        260 
NIVAGNPRVV KAMLANMRDE LSDALKR

« Hide

References

[1]"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli."
Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R.
Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed: 12471157] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O6:H1 / CFT073 / ATCC 700928 / UPEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014075 Genomic DNA. Translation: AAN81509.1.
RefSeqNP_754941.1. NC_004431.1.

3D structure databases

ProteinModelPortalP0ADG5.
SMRP0ADG5. Positions 1-262.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000043953; EBESCP00000042302; EBESCG00000043003.
GeneID1038758.
GenomeReviewsGene locus c3059 in contig AE014075_GR.
KEGGecc:c3059.
PATRIC18283974. VBIEscCol75197_2887.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000010909.
HOGENOMHBG730251.
OMATGFPFKQ.
PhylomeDBP0ADG5.
ProtClustDBPRK10757.

Family and domain databases

InterProIPR020583. Inositol_monoP_metal-BS.
IPR000760. Inositol_monophosphatase.
IPR020550. Inositol_monophosphatase_CS.
IPR022337. Inositol_monophosphatase_SuhB.
[Graphical view]
KOK01092.
PANTHERPTHR20854. Inositol_P. 1 hit.
PfamPF00459. Inositol_P. 1 hit.
[Graphical view]
PRINTSPR00377. IMPHPHTASES.
PR01959. SBIMPHPHTASE.
PROSITEPS00629. IMP_1. 1 hit.
PS00630. IMP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSUHB_ECOL6
AccessionPrimary (citable) accession number: P0ADG5
Secondary accession number(s): P22783, P77511, Q8X2E6
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents