P0ADB7 (ECNB_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Entericidin B

Gene names

Name:	ecnB
Synonyms:	yjeU
Ordered Locus Names:	b4411, JW4108

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	48 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays a role in the bacteriolysis. Is activated under conditions of high osmolarity by the factor sigma S. Entericidin A functions as an antidote.
Subcellular location	Cell membrane; Lipid-anchor.
Sequence similarities	Belongs to the EcnA/EcnB lipoprotein family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to toxin Inferred from electronic annotation. Source: InterPro
Cellular_component	plasma membrane Inferred from direct assay Ref.1. Source: EcoCyc
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Peptide	22 – 48	27	Entericidin B		PRO_0000018170
Amino acid modifications
	Lipidation	22	1	N-palmitoyl cysteine Probable
	Lipidation	22	1	S-diacylglycerol cysteine Probable

Sequences

	Sequence		Length	Mass (Da)
	P0ADB7 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 9814A908CA6A70CC	FASTA	48	4,810
	10 20 30 40 MVKKTIAAIF SVLVLSTVLT ACNTTRGVGE DISDGGNAIS GAATKAQQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The entericidin locus of Escherichia coli and its implications for programmed bacterial cell death." Bishop R.E., Leskiw B.K., Hodges R.S., Kay C.M., Weiner J.H. J. Mol. Biol. 280:583-596(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12 / CS520.
[2]	"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes." Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R. Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U21726 Genomic DNA. Translation: AAC46454.1. U14003 Genomic DNA. No translation available. U00096 Genomic DNA. Translation: AAT48242.1. AP009048 Genomic DNA. Translation: BAE78151.1.
RefSeq	YP_026284.1. NC_000913.2. YP_492292.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P0ADB7.
ModBase	Search...
Protein-protein interaction databases
STRING	511145.b4411.
Protein family/group databases
TCDB	9.B.13.1.1. putative pore-forming entericidin (ECN) family.
Proteomic databases
PaxDb	P0ADB7.
PRIDE	P0ADB7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAT48242; AAT48242; b4411. BAE78151; BAE78151; BAE78151.
GeneID	12932139. 2847737.
KEGG	ecj:Y75_p4036. eco:b4411.
PATRIC	32123867. VBIEscCol129921_4281.
Organism-specific databases
EchoBASE	EB4091.
EcoGene	EG14345. ecnB.
Phylogenomic databases
eggNOG	COG5510.
HOGENOM	HOG000211677.
KO	K16348.
ProtClustDB	PRK10081.
Enzyme and pathway databases
BioCyc	EcoCyc:MONOMER0-1563. ECOL316407:JW4108-MONOMER.
Gene expression databases
Genevestigator	P0ADB7.
Family and domain databases
InterPro	IPR012556. Entericidin. [Graphical view]
Pfam	PF08085. Entericidin. 1 hit. [Graphical view]
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ECNB_ECOLI

Accession

Primary (citable) accession number: P0ADB7
Secondary accession number(s): P56549, Q2M6F5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program