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Protein

Entericidin A

Gene

ecnA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Acts as antidote to the effect of entericidin B.

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-1562.
ECOL316407:JW5737-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Entericidin A
Gene namesi
Name:ecnA
Ordered Locus Names:b4410, JW5737
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14372. ecnA.

Subcellular locationi

GO - Cellular componenti

  • membrane Source: EcoCyc
  • plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818PROSITE-ProRule annotationAdd
BLAST
Peptidei19 – 4123Entericidin APRO_0000018168Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi19 – 191N-palmitoyl cysteineCurated
Lipidationi19 – 191S-diacylglycerol cysteineCurated

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiP0ADB4.

Interactioni

Protein-protein interaction databases

BioGridi4262117. 282 interactions.
STRINGi511145.b4410.

Structurei

3D structure databases

ProteinModelPortaliP0ADB4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the EcnA/EcnB lipoprotein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107PEH. Bacteria.
COG5510. LUCA.
HOGENOMiHOG000211677.
KOiK16347.
OrthoDBiEOG6NSGQ5.

Family and domain databases

InterProiIPR012556. Entericidin.
[Graphical view]
PfamiPF08085. Entericidin. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0ADB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MMKRLIVLVL LASTLLTGCN TARGFGEDIK HLGNSISRAA S
Length:41
Mass (Da):4,359
Last modified:December 6, 2005 - v1
Checksum:i35FD3CE6B025743C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U21726 Genomic DNA. Translation: AAC46455.1.
U14003 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAT48241.1.
AP009048 Genomic DNA. Translation: BAE78150.1.
RefSeqiWP_000977757.1. NZ_LN832404.1.
YP_026283.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48241; AAT48241; b4410.
BAE78150; BAE78150; BAE78150.
GeneIDi2847736.
KEGGiecj:JW5737.
eco:b4410.
PATRICi32123865. VBIEscCol129921_4280.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U21726 Genomic DNA. Translation: AAC46455.1.
U14003 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAT48241.1.
AP009048 Genomic DNA. Translation: BAE78150.1.
RefSeqiWP_000977757.1. NZ_LN832404.1.
YP_026283.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP0ADB4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262117. 282 interactions.
STRINGi511145.b4410.

Proteomic databases

PaxDbiP0ADB4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48241; AAT48241; b4410.
BAE78150; BAE78150; BAE78150.
GeneIDi2847736.
KEGGiecj:JW5737.
eco:b4410.
PATRICi32123865. VBIEscCol129921_4280.

Organism-specific databases

EchoBASEiEB4115.
EcoGeneiEG14372. ecnA.

Phylogenomic databases

eggNOGiENOG4107PEH. Bacteria.
COG5510. LUCA.
HOGENOMiHOG000211677.
KOiK16347.
OrthoDBiEOG6NSGQ5.

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-1562.
ECOL316407:JW5737-MONOMER.

Miscellaneous databases

PROiP0ADB4.

Family and domain databases

InterProiIPR012556. Entericidin.
[Graphical view]
PfamiPF08085. Entericidin. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The entericidin locus of Escherichia coli and its implications for programmed bacterial cell death."
    Bishop R.E., Leskiw B.K., Hodges R.S., Kay C.M., Weiner J.H.
    J. Mol. Biol. 280:583-596(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / CS520.
  2. "Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
    Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
    Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiECNA_ECOLI
AccessioniPrimary (citable) accession number: P0ADB4
Secondary accession number(s): P56548, Q2M6F6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: March 16, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.