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Protein

Trp operon leader peptide

Gene

trpL

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

This protein is involved in control of the biosynthesis of tryptophan.

GO - Biological processi

  • regulation of tryptophan metabolic process Source: EcoCyc
  • tryptophan biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Leader peptide

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11274-MONOMER.
ECOL316407:JW1257-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Trp operon leader peptide
Gene namesi
Name:trpL
Synonyms:trpEE
Ordered Locus Names:b1265, JW1257
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11274. trpL.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Peptidei1 – 1414Trp operon leader peptidePRO_0000044023Add
BLAST

Family & Domainsi

Phylogenomic databases

KOiK07802.

Family and domain databases

InterProiIPR013205. Leader_Trp_op.
[Graphical view]
PfamiPF08255. Leader_Trp. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Length:14
Mass (Da):1,723
Last modified:July 21, 1986 - v1
Checksum:i5B79306E3E804A37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01714 Genomic DNA. Translation: AAA57296.1.
U00096 Genomic DNA. Translation: AAC74347.1.
AP009048 Genomic DNA. Translation: BAE76395.1.
PIRiA03589. LFECW.
RefSeqiNP_415781.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC74347; AAC74347; b1265.
BAE76395; BAE76395; BAE76395.
GeneIDi945856.
KEGGiecj:JW1257.
eco:b1265.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01714 Genomic DNA. Translation: AAA57296.1.
U00096 Genomic DNA. Translation: AAC74347.1.
AP009048 Genomic DNA. Translation: BAE76395.1.
PIRiA03589. LFECW.
RefSeqiNP_415781.1. NC_000913.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74347; AAC74347; b1265.
BAE76395; BAE76395; BAE76395.
GeneIDi945856.
KEGGiecj:JW1257.
eco:b1265.

Organism-specific databases

EchoBASEiEB1252.
EcoGeneiEG11274. trpL.

Phylogenomic databases

KOiK07802.

Enzyme and pathway databases

BioCyciEcoCyc:EG11274-MONOMER.
ECOL316407:JW1257-MONOMER.

Miscellaneous databases

PROiP0AD92.

Family and domain databases

InterProiIPR013205. Leader_Trp_op.
[Graphical view]
PfamiPF08255. Leader_Trp. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLPW_ECOLI
AccessioniPrimary (citable) accession number: P0AD92
Secondary accession number(s): P03053, Q2MBG1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 11, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.