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Protein

Thr operon leader peptide

Gene

thrL

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein is involved in control of the biosynthesis of threonine.

GO - Biological processi

  • threonine biosynthetic process Source: UniProtKB-HAMAP
  • transcriptional attenuation Source: EcoCyc
  • transcriptional attenuation by ribosome Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Leader peptide

Keywords - Biological processi

Amino-acid biosynthesis, Threonine biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11277-MONOMER.
ECOL316407:JW4367-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thr operon leader peptideUniRule annotation
Alternative name(s):
Thr operon attenuatorUniRule annotation
Gene namesi
Name:thrLUniRule annotation
Ordered Locus Names:b0001, JW4367
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11277. thrL.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00000440071 – 21Thr operon leader peptideAdd BLAST21

Proteomic databases

PaxDbiP0AD86.
PRIDEiP0AD86.

Interactioni

Protein-protein interaction databases

BioGridi4261932. 4 interactors.
STRINGi511145.b0001.

Family & Domainsi

Sequence similaritiesi

Belongs to the Thr operon leader peptide family.UniRule annotation

Phylogenomic databases

KOiK08278.

Family and domain databases

HAMAPiMF_01907. Leader_Thr. 1 hit.
InterProiIPR011720. Thr_lead_pept.
[Graphical view]
PfamiPF08254. Leader_Thr. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02077. thr_lead_pep. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AD86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
MKRISTTITT TITITTGNGA G
Length:21
Mass (Da):2,138
Last modified:July 21, 1986 - v1
Checksum:i6A9C9167F89EECE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01706 Genomic DNA. Translation: AAA83913.1.
V00360 Genomic DNA. Translation: CAA23658.1.
X68872 Genomic DNA. Translation: CAA48733.1.
M28570 Genomic DNA. Translation: AAA24672.1.
U14003 Genomic DNA. Translation: AAA97300.1.
U00096 Genomic DNA. Translation: AAC73112.1.
AP009048 Genomic DNA. Translation: BAE76026.1.
PIRiA03595. LFECT.
RefSeqiNP_414542.1. NC_000913.3.
WP_001386572.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73112; AAC73112; b0001.
BAE76026; BAE76026; BAE76026.
GeneIDi944742.
KEGGiecj:JW4367.
eco:b0001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01706 Genomic DNA. Translation: AAA83913.1.
V00360 Genomic DNA. Translation: CAA23658.1.
X68872 Genomic DNA. Translation: CAA48733.1.
M28570 Genomic DNA. Translation: AAA24672.1.
U14003 Genomic DNA. Translation: AAA97300.1.
U00096 Genomic DNA. Translation: AAC73112.1.
AP009048 Genomic DNA. Translation: BAE76026.1.
PIRiA03595. LFECT.
RefSeqiNP_414542.1. NC_000913.3.
WP_001386572.1. NZ_LN832404.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261932. 4 interactors.
STRINGi511145.b0001.

Proteomic databases

PaxDbiP0AD86.
PRIDEiP0AD86.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73112; AAC73112; b0001.
BAE76026; BAE76026; BAE76026.
GeneIDi944742.
KEGGiecj:JW4367.
eco:b0001.

Organism-specific databases

EchoBASEiEB1255.
EcoGeneiEG11277. thrL.

Phylogenomic databases

KOiK08278.

Enzyme and pathway databases

BioCyciEcoCyc:EG11277-MONOMER.
ECOL316407:JW4367-MONOMER.

Miscellaneous databases

PROiP0AD86.

Family and domain databases

HAMAPiMF_01907. Leader_Thr. 1 hit.
InterProiIPR011720. Thr_lead_pept.
[Graphical view]
PfamiPF08254. Leader_Thr. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02077. thr_lead_pep. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiLPT_ECOLI
AccessioniPrimary (citable) accession number: P0AD86
Secondary accession number(s): P03059, Q2MCI0, Q6LEL1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 2, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.