P0AD44 (YFHG_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YfhG

Gene names

Name:	yfhG
Ordered Locus Names:	b2555, JW2539

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	237 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Post-translational modification	Exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. Can also be exported by the Sec system.
Sequence caution	The sequence AAA79817.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Domain	Signal
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Tat-type signal Potential
	Chain	26 – 237	212	Uncharacterized protein YfhG		PRO_0000169249

Sequences

	Sequence		Length	Mass (Da)
	P0AD44 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 594D0C495759098D	FASTA	237	27,348
	10 20 30 40 50 60 MRHIFQRLLP RRLWLAGLPC LALLGCVQNH NKPAIDTPAE EKIPVYQLAD YLSTECSDIW 70 80 90 100 110 120 ALQGKSTETN PLYWLRAMDC ADRLMPAQSR QQARQYDDGS WQNTFKQGIL LADAKITPYE 130 140 150 160 170 180 RRQLVARIEA LSTEIPAQVR PLYQLWRDGQ ALQLQLAEER QRYSKLQQSS DSELDTLRQQ 190 200 210 220 230 HHVLQQQLEL TTRKLENLTD IERQLSTRKP AGNFSPDTPH ESEKPAPSTH EVTPDEP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The glnB region of the Escherichia coli chromosome." Liu J., Magasanik B. J. Bacteriol. 175:7441-7449(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T. , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T. DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 135-237. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]	"Export pathway selectivity of Escherichia coli twin arginine translocation signal peptides." Tullman-Ercek D., DeLisa M.P., Kawarasaki Y., Iranpour P., Ribnicky B., Palmer T., Georgiou G. J. Biol. Chem. 282:8309-8316(2007) [PubMed] [Europe PMC] [Abstract] Cited for: EXPORT VIA THE TAT-SYSTEM AND THE SEC-SYSTEM.

Cross-references

Sequence databases
EMBL GenBank DDBJ	S67014 Genomic DNA. Translation: AAB28777.1. U36841 Genomic DNA. Translation: AAA79817.1. Different initiation. U00096 Genomic DNA. Translation: AAC75608.1. AP009048 Genomic DNA. Translation: BAA16463.2.
PIR	A49940.
RefSeq	NP_417050.1. NC_000913.2. YP_490783.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P0AD44.
ModBase	Search...
Protein-protein interaction databases
STRING	511145.b2555.
Proteomic databases
PRIDE	P0AD44.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC75608; AAC75608; b2555. BAA16463; BAA16463; BAA16463.
GeneID	12930209. 947010.
KEGG	ecj:Y75_p2508. eco:b2555.
PATRIC	32120509. VBIEscCol129921_2657.
Organism-specific databases
EchoBASE	EB2060.
EcoGene	EG12139. yfhG.
Phylogenomic databases
eggNOG	NOG06037.
HOGENOM	HOG000123524.
OMA	AMNNALY.
ProtClustDB	PRK10722.
Enzyme and pathway databases
BioCyc	EcoCyc:EG12139-MONOMER. ECOL316407:JW2539-MONOMER.
Gene expression databases
Genevestigator	P0AD44.
Family and domain databases
InterPro	IPR025262. QseG. [Graphical view]
Pfam	PF13942. Lipoprotein_20. 1 hit. [Graphical view]
PROSITE	PS51318. TAT. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YFHG_ECOLI

Accession

Primary (citable) accession number: P0AD44
Secondary accession number(s): P37328, P76997

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program