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Protein

Inner membrane protein YejM

Gene

yejM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG12049-MONOMER.
ECOL316407:JW2176-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YejM
Gene namesi
Name:yejM
Synonyms:yejN
Ordered Locus Names:b2188, JW2176
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12049. yejM.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2020CytoplasmicSequence analysisAdd
BLAST
Transmembranei21 – 4323HelicalSequence analysisAdd
BLAST
Topological domaini44 – 5714PeriplasmicSequence analysisAdd
BLAST
Transmembranei58 – 8023HelicalSequence analysisAdd
BLAST
Topological domaini81 – 844CytoplasmicSequence analysis
Transmembranei85 – 10319HelicalSequence analysisAdd
BLAST
Topological domaini104 – 13431PeriplasmicSequence analysisAdd
BLAST
Transmembranei135 – 15723HelicalSequence analysisAdd
BLAST
Topological domaini158 – 16811CytoplasmicSequence analysisAdd
BLAST
Transmembranei169 – 19123HelicalSequence analysisAdd
BLAST
Topological domaini192 – 586395PeriplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 586586Inner membrane protein YejMPRO_0000169165Add
BLAST

Proteomic databases

PaxDbiP0AD27.

Interactioni

Protein-protein interaction databases

BioGridi4260478. 11 interactions.
STRINGi511145.b2188.

Structurei

3D structure databases

ProteinModelPortaliP0AD27.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To H.influenzae HI_0842.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E68. Bacteria.
COG3083. LUCA.
HOGENOMiHOG000275802.
InParanoidiP0AD27.
KOiK07014.
OMAiYAFIIDW.
OrthoDBiEOG61KBCH.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR000917. Sulfatase_N.
IPR012159. YejM.
IPR024588. YejM_N.
[Graphical view]
PfamiPF11893. DUF3413. 1 hit.
PF00884. Sulfatase. 1 hit.
[Graphical view]
PIRSFiPIRSF004950. Mmb_sulf_HI0842. 1 hit.
SUPFAMiSSF53649. SSF53649. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AD27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTHRQRYRE KVSQMVSWGH WFALFNILLS LVIGSRYLFI ADWPTTLAGR
60 70 80 90 100
IYSYVSIIGH FSFLVFATYL LILFPLTFIV GSQRLMRFLS VILATAGMTL
110 120 130 140 150
LLIDSEVFTR FHLHLNPIVW QLVINPDENE MARDWQLMFI SVPVILLLEL
160 170 180 190 200
VFATWSWQKL RSLTRRRRFA RPLAAFLFIA FIASHVVYIW ADANFYRPIT
210 220 230 240 250
MQRANLPLSY PMTARRFLEK HGLLDAQEYQ RRLIEQGNPD AVSVQYPLSE
260 270 280 290 300
LRYRDMGTGQ NVLLITVDGL NYSRFEKQMP ALAGFAEQNI SFTRHMSSGN
310 320 330 340 350
TTDNGIFGLF YGISPSYMDG ILSTRTPAAL ITALNQQGYQ LGLFSSDGFT
360 370 380 390 400
SPLYRQALLS DFSMPSVRTQ SDEQTATQWI NWLGRYAQED NRWFSWVSFN
410 420 430 440 450
GTNIDDSNQQ AFARKYSRAA GNVDDQINRV LNALRDSGKL DNTVVIITAG
460 470 480 490 500
RGIPLSEEEE TFDWSHGHLQ VPLVIHWPGT PAQRINALTD HTDLMTTLMQ
510 520 530 540 550
RLLHVSTPAS EYSQGQDLFN PQRRHYWVTA ADNDTLAITT PKKTLVLNNN
560 570 580
GKYRTYNLRG ERVKDEKPQL SLLLQVLTDE KRFIAN
Length:586
Mass (Da):67,296
Last modified:November 22, 2005 - v1
Checksum:i0460F8C00A0D5465
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00008 Genomic DNA. Translation: AAA16384.1.
U00096 Genomic DNA. Translation: AAC75249.1.
AP009048 Genomic DNA. Translation: BAE76653.1.
PIRiC64988.
RefSeqiNP_416693.1. NC_000913.3.
WP_000256203.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75249; AAC75249; b2188.
BAE76653; BAE76653; BAE76653.
GeneIDi946685.
KEGGiecj:JW2176.
eco:b2188.
PATRICi32119733. VBIEscCol129921_2277.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00008 Genomic DNA. Translation: AAA16384.1.
U00096 Genomic DNA. Translation: AAC75249.1.
AP009048 Genomic DNA. Translation: BAE76653.1.
PIRiC64988.
RefSeqiNP_416693.1. NC_000913.3.
WP_000256203.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AD27.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260478. 11 interactions.
STRINGi511145.b2188.

Proteomic databases

PaxDbiP0AD27.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75249; AAC75249; b2188.
BAE76653; BAE76653; BAE76653.
GeneIDi946685.
KEGGiecj:JW2176.
eco:b2188.
PATRICi32119733. VBIEscCol129921_2277.

Organism-specific databases

EchoBASEiEB1981.
EcoGeneiEG12049. yejM.

Phylogenomic databases

eggNOGiENOG4105E68. Bacteria.
COG3083. LUCA.
HOGENOMiHOG000275802.
InParanoidiP0AD27.
KOiK07014.
OMAiYAFIIDW.
OrthoDBiEOG61KBCH.

Enzyme and pathway databases

BioCyciEcoCyc:EG12049-MONOMER.
ECOL316407:JW2176-MONOMER.

Miscellaneous databases

PROiP0AD27.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR000917. Sulfatase_N.
IPR012159. YejM.
IPR024588. YejM_N.
[Graphical view]
PfamiPF11893. DUF3413. 1 hit.
PF00884. Sulfatase. 1 hit.
[Graphical view]
PIRSFiPIRSF004950. Mmb_sulf_HI0842. 1 hit.
SUPFAMiSSF53649. SSF53649. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Automated multiplex sequencing of the E.coli genome."
    Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K., Church G.M.
    Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / BHB2600.
  2. Robison K.
    Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYEJM_ECOLI
AccessioniPrimary (citable) accession number: P0AD27
Secondary accession number(s): P33922, P33923, Q2MAQ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: January 20, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.