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Protein

Inner membrane protein YejM

Gene

yejM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG12049-MONOMER.
ECOL316407:JW2176-MONOMER.

Protein family/group databases

TCDBi2.A.127.1.2. enterobacterial cardiolipin transporter (clt) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YejM
Gene namesi
Name:yejM
Synonyms:yejN
Ordered Locus Names:b2188, JW2176
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12049. yejM.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 20CytoplasmicSequence analysisAdd BLAST20
Transmembranei21 – 43HelicalSequence analysisAdd BLAST23
Topological domaini44 – 57PeriplasmicSequence analysisAdd BLAST14
Transmembranei58 – 80HelicalSequence analysisAdd BLAST23
Topological domaini81 – 84CytoplasmicSequence analysis4
Transmembranei85 – 103HelicalSequence analysisAdd BLAST19
Topological domaini104 – 134PeriplasmicSequence analysisAdd BLAST31
Transmembranei135 – 157HelicalSequence analysisAdd BLAST23
Topological domaini158 – 168CytoplasmicSequence analysisAdd BLAST11
Transmembranei169 – 191HelicalSequence analysisAdd BLAST23
Topological domaini192 – 586PeriplasmicSequence analysisAdd BLAST395

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001691651 – 586Inner membrane protein YejMAdd BLAST586

Proteomic databases

PaxDbiP0AD27.
PRIDEiP0AD27.

Interactioni

Protein-protein interaction databases

BioGridi4260478. 11 interactors.
STRINGi511145.b2188.

Structurei

Secondary structure

1586
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi253 – 256Combined sources4
Beta strandi262 – 270Combined sources9
Helixi275 – 278Combined sources4
Helixi280 – 287Combined sources8
Beta strandi289 – 296Combined sources8
Helixi302 – 311Combined sources10
Helixi315 – 317Combined sources3
Helixi318 – 323Combined sources6
Helixi329 – 336Combined sources8
Beta strandi340 – 347Combined sources8
Helixi352 – 356Combined sources5
Helixi358 – 361Combined sources4
Beta strandi366 – 368Combined sources3
Helixi372 – 385Combined sources14
Helixi387 – 389Combined sources3
Beta strandi391 – 399Combined sources9
Helixi409 – 436Combined sources28
Beta strandi443 – 452Combined sources10
Helixi457 – 460Combined sources4
Helixi466 – 469Combined sources4
Beta strandi473 – 476Combined sources4
Beta strandi483 – 485Combined sources3
Helixi491 – 501Combined sources11
Helixi509 – 511Combined sources3
Beta strandi528 – 531Combined sources4
Beta strandi533 – 539Combined sources7
Beta strandi541 – 548Combined sources8
Beta strandi553 – 557Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5I5HX-ray1.65A1-586[»]
ProteinModelPortaliP0AD27.
SMRiP0AD27.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To H.influenzae HI_0842.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E68. Bacteria.
COG3083. LUCA.
HOGENOMiHOG000275802.
InParanoidiP0AD27.
KOiK07014.
OMAiYAFIIDW.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR000917. Sulfatase_N.
IPR012159. YejM.
IPR024588. YejM_N.
[Graphical view]
PfamiPF11893. DUF3413. 1 hit.
PF00884. Sulfatase. 1 hit.
[Graphical view]
PIRSFiPIRSF004950. Mmb_sulf_HI0842. 1 hit.
SUPFAMiSSF53649. SSF53649. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AD27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTHRQRYRE KVSQMVSWGH WFALFNILLS LVIGSRYLFI ADWPTTLAGR
60 70 80 90 100
IYSYVSIIGH FSFLVFATYL LILFPLTFIV GSQRLMRFLS VILATAGMTL
110 120 130 140 150
LLIDSEVFTR FHLHLNPIVW QLVINPDENE MARDWQLMFI SVPVILLLEL
160 170 180 190 200
VFATWSWQKL RSLTRRRRFA RPLAAFLFIA FIASHVVYIW ADANFYRPIT
210 220 230 240 250
MQRANLPLSY PMTARRFLEK HGLLDAQEYQ RRLIEQGNPD AVSVQYPLSE
260 270 280 290 300
LRYRDMGTGQ NVLLITVDGL NYSRFEKQMP ALAGFAEQNI SFTRHMSSGN
310 320 330 340 350
TTDNGIFGLF YGISPSYMDG ILSTRTPAAL ITALNQQGYQ LGLFSSDGFT
360 370 380 390 400
SPLYRQALLS DFSMPSVRTQ SDEQTATQWI NWLGRYAQED NRWFSWVSFN
410 420 430 440 450
GTNIDDSNQQ AFARKYSRAA GNVDDQINRV LNALRDSGKL DNTVVIITAG
460 470 480 490 500
RGIPLSEEEE TFDWSHGHLQ VPLVIHWPGT PAQRINALTD HTDLMTTLMQ
510 520 530 540 550
RLLHVSTPAS EYSQGQDLFN PQRRHYWVTA ADNDTLAITT PKKTLVLNNN
560 570 580
GKYRTYNLRG ERVKDEKPQL SLLLQVLTDE KRFIAN
Length:586
Mass (Da):67,296
Last modified:November 22, 2005 - v1
Checksum:i0460F8C00A0D5465
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00008 Genomic DNA. Translation: AAA16384.1.
U00096 Genomic DNA. Translation: AAC75249.1.
AP009048 Genomic DNA. Translation: BAE76653.1.
PIRiC64988.
RefSeqiNP_416693.1. NC_000913.3.
WP_000256203.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75249; AAC75249; b2188.
BAE76653; BAE76653; BAE76653.
GeneIDi946685.
KEGGiecj:JW2176.
eco:b2188.
PATRICi32119733. VBIEscCol129921_2277.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00008 Genomic DNA. Translation: AAA16384.1.
U00096 Genomic DNA. Translation: AAC75249.1.
AP009048 Genomic DNA. Translation: BAE76653.1.
PIRiC64988.
RefSeqiNP_416693.1. NC_000913.3.
WP_000256203.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5I5HX-ray1.65A1-586[»]
ProteinModelPortaliP0AD27.
SMRiP0AD27.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260478. 11 interactors.
STRINGi511145.b2188.

Protein family/group databases

TCDBi2.A.127.1.2. enterobacterial cardiolipin transporter (clt) family.

Proteomic databases

PaxDbiP0AD27.
PRIDEiP0AD27.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75249; AAC75249; b2188.
BAE76653; BAE76653; BAE76653.
GeneIDi946685.
KEGGiecj:JW2176.
eco:b2188.
PATRICi32119733. VBIEscCol129921_2277.

Organism-specific databases

EchoBASEiEB1981.
EcoGeneiEG12049. yejM.

Phylogenomic databases

eggNOGiENOG4105E68. Bacteria.
COG3083. LUCA.
HOGENOMiHOG000275802.
InParanoidiP0AD27.
KOiK07014.
OMAiYAFIIDW.

Enzyme and pathway databases

BioCyciEcoCyc:EG12049-MONOMER.
ECOL316407:JW2176-MONOMER.

Miscellaneous databases

PROiP0AD27.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR000917. Sulfatase_N.
IPR012159. YejM.
IPR024588. YejM_N.
[Graphical view]
PfamiPF11893. DUF3413. 1 hit.
PF00884. Sulfatase. 1 hit.
[Graphical view]
PIRSFiPIRSF004950. Mmb_sulf_HI0842. 1 hit.
SUPFAMiSSF53649. SSF53649. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYEJM_ECOLI
AccessioniPrimary (citable) accession number: P0AD27
Secondary accession number(s): P33922, P33923, Q2MAQ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: November 30, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.