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Protein

Inner membrane protein YohK

Gene

yohK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG12024-MONOMER.
ECOL316407:JW2130-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YohK
Gene namesi
Name:yohK
Ordered Locus Names:b2142, JW2130
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12024. yohK.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 11PeriplasmicSequence analysis
Transmembranei2 – 2221HelicalSequence analysisAdd
BLAST
Topological domaini23 – 297CytoplasmicSequence analysis
Transmembranei30 – 5021HelicalSequence analysisAdd
BLAST
Topological domaini51 – 9040PeriplasmicSequence analysisAdd
BLAST
Transmembranei91 – 11121HelicalSequence analysisAdd
BLAST
Topological domaini112 – 1187CytoplasmicSequence analysis
Transmembranei119 – 13921HelicalSequence analysisAdd
BLAST
Transmembranei140 – 16021HelicalSequence analysisAdd
BLAST
Topological domaini161 – 20848CytoplasmicSequence analysisAdd
BLAST
Transmembranei209 – 22921HelicalSequence analysisAdd
BLAST
Topological domaini230 – 2312PeriplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 231231Inner membrane protein YohKPRO_0000169140Add
BLAST

Proteomic databases

PaxDbiP0AD19.

Interactioni

Protein-protein interaction databases

BioGridi4260834. 3 interactions.
STRINGi511145.b2142.

Structurei

3D structure databases

ProteinModelPortaliP0AD19.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41067MG. Bacteria.
COG1346. LUCA.
HOGENOMiHOG000253604.
InParanoidiP0AD19.
OMAiQMHQIRA.
OrthoDBiEOG6NPMDR.
PhylomeDBiP0AD19.

Family and domain databases

InterProiIPR005261. CHP00659.
IPR007300. CidB/LrgB.
[Graphical view]
PfamiPF04172. LrgB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00659. TIGR00659. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AD19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMANIWWSLP LTLIVFFAAR KLAARYKFPL LNPLLVAMVV IIPFLMLTGI
60 70 80 90 100
SYDSYFKGSE VLNDLLQPAV VALAYPLYEQ LHQIRARWKS IITICFIGSV
110 120 130 140 150
VAMVTGTSVA LLMGASPEIA ASILPKSVTT PIAMAVGGSI GGIPAISAVC
160 170 180 190 200
VIFVGILGAV FGHTLLNAMR IRTKAARGLA MGTASHALGT ARCAELDYQE
210 220 230
GAFSSLALVL CGIITSLIAP FLFPIILAVM G
Length:231
Mass (Da):24,470
Last modified:November 22, 2005 - v1
Checksum:i178A705904384DD0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti206 – 23126LALVL…LAVMG → ASAGVMRDNYFADRTVPFPD YSGSNGLKFAMRRAFLMYVS RVA (Ref. 1) CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00007 Genomic DNA. Translation: AAA60505.1.
U00096 Genomic DNA. Translation: AAC75203.1.
AP009048 Genomic DNA. Translation: BAE76619.1.
X16419 Genomic DNA. No translation available.
PIRiE64982.
RefSeqiNP_416647.1. NC_000913.3.
WP_000968208.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75203; AAC75203; b2142.
BAE76619; BAE76619; BAE76619.
GeneIDi949125.
KEGGiecj:JW2130.
eco:b2142.
PATRICi32119627. VBIEscCol129921_2224.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00007 Genomic DNA. Translation: AAA60505.1.
U00096 Genomic DNA. Translation: AAC75203.1.
AP009048 Genomic DNA. Translation: BAE76619.1.
X16419 Genomic DNA. No translation available.
PIRiE64982.
RefSeqiNP_416647.1. NC_000913.3.
WP_000968208.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AD19.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260834. 3 interactions.
STRINGi511145.b2142.

Proteomic databases

PaxDbiP0AD19.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75203; AAC75203; b2142.
BAE76619; BAE76619; BAE76619.
GeneIDi949125.
KEGGiecj:JW2130.
eco:b2142.
PATRICi32119627. VBIEscCol129921_2224.

Organism-specific databases

EchoBASEiEB1959.
EcoGeneiEG12024. yohK.

Phylogenomic databases

eggNOGiENOG41067MG. Bacteria.
COG1346. LUCA.
HOGENOMiHOG000253604.
InParanoidiP0AD19.
OMAiQMHQIRA.
OrthoDBiEOG6NPMDR.
PhylomeDBiP0AD19.

Enzyme and pathway databases

BioCyciEcoCyc:EG12024-MONOMER.
ECOL316407:JW2130-MONOMER.

Miscellaneous databases

PROiP0AD19.

Family and domain databases

InterProiIPR005261. CHP00659.
IPR007300. CidB/LrgB.
[Graphical view]
PfamiPF04172. LrgB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00659. TIGR00659. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K., Church G.M.
    Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / BHB2600.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "CRP/cAMP- and CytR-regulated promoters in Escherichia coli K12: the cdd promoter."
    Valentin-Hansen P., Holst B., Josephsen J., Hammer K., Albrechtsen B.
    Mol. Microbiol. 3:1385-1390(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 192-231.
    Strain: K12.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYOHK_ECOLI
AccessioniPrimary (citable) accession number: P0AD19
Secondary accession number(s): P33373, Q2MAT7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: January 20, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.