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P0ACZ3

- ETP_ECO57

UniProt

P0ACZ3 - ETP_ECO57

Protein

Low molecular weight protein-tyrosine-phosphatase etp

Gene

etp

Organism
Escherichia coli O157:H7
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (22 Nov 2005)
      Previous versions | rss
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    Functioni

    Dephosphorylates etk.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei13 – 131NucleophileBy similarity
    Active sitei18 – 181By similarity
    Active sitei119 – 1191Proton donorBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Enzyme and pathway databases

    BioCyciECOL386585:GJFA-1131-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Low molecular weight protein-tyrosine-phosphatase etp (EC:3.1.3.48)
    Gene namesi
    Name:etp
    Ordered Locus Names:Z1399, ECs1138
    OrganismiEscherichia coli O157:H7
    Taxonomic identifieri83334 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000558: Chromosome, UP000002519: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 148148Low molecular weight protein-tyrosine-phosphatase etpPRO_0000046577Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi155864.Z1399.

    Structurei

    3D structure databases

    ProteinModelPortaliP0ACZ3.
    SMRiP0ACZ3. Positions 4-146.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0394.
    HOGENOMiHOG000273091.
    KOiK01104.
    OMAiHAYQLID.
    OrthoDBiEOG63VC26.

    Family and domain databases

    InterProiIPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view]
    PANTHERiPTHR11717. PTHR11717. 1 hit.
    PfamiPF01451. LMWPc. 1 hit.
    [Graphical view]
    PRINTSiPR00719. LMWPTPASE.
    SMARTiSM00226. LMWPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52788. SSF52788. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0ACZ3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAQLKFNSIL VVCTGNICRS PIGERLLRKR LPGVKVKSAG VHGLVKHPAD    50
    ATAADVAANH GVSLEGHAGR KLTAEMARNY DLILAMESEH IAQVTAIAPE 100
    VRGKTMLFGQ WLEQKEIPDP YRKSQDAFEH VYGMLERASQ EWAKRLSR 148
    Length:148
    Mass (Da):16,386
    Last modified:November 22, 2005 - v1
    Checksum:i136DA7AEF6AE8F0C
    GO

    Sequence cautioni

    The sequence AAG55530.1 differs from that shown. Reason: Erroneous initiation.
    The sequence BAB34561.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005174 Genomic DNA. Translation: AAG55530.1. Different initiation.
    BA000007 Genomic DNA. Translation: BAB34561.1. Different initiation.
    RefSeqiNP_286919.2. NC_002655.2.
    NP_309165.2. NC_002695.1.

    Genome annotation databases

    EnsemblBacteriaiAAG55530; AAG55530; Z1399.
    BAB34561; BAB34561; BAB34561.
    GeneIDi914076.
    959046.
    KEGGiece:Z1399.
    ecs:ECs1138.
    PATRICi18351537. VBIEscCol44059_5347.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005174 Genomic DNA. Translation: AAG55530.1 . Different initiation.
    BA000007 Genomic DNA. Translation: BAB34561.1 . Different initiation.
    RefSeqi NP_286919.2. NC_002655.2.
    NP_309165.2. NC_002695.1.

    3D structure databases

    ProteinModelPortali P0ACZ3.
    SMRi P0ACZ3. Positions 4-146.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 155864.Z1399.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG55530 ; AAG55530 ; Z1399 .
    BAB34561 ; BAB34561 ; BAB34561 .
    GeneIDi 914076.
    959046.
    KEGGi ece:Z1399.
    ecs:ECs1138.
    PATRICi 18351537. VBIEscCol44059_5347.

    Phylogenomic databases

    eggNOGi COG0394.
    HOGENOMi HOG000273091.
    KOi K01104.
    OMAi HAYQLID.
    OrthoDBi EOG63VC26.

    Enzyme and pathway databases

    BioCyci ECOL386585:GJFA-1131-MONOMER.

    Family and domain databases

    InterProi IPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view ]
    PANTHERi PTHR11717. PTHR11717. 1 hit.
    Pfami PF01451. LMWPc. 1 hit.
    [Graphical view ]
    PRINTSi PR00719. LMWPTPASE.
    SMARTi SM00226. LMWPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52788. SSF52788. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
    2. "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
      Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.
      , Kuhara S., Shiba T., Hattori M., Shinagawa H.
      DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

    Entry informationi

    Entry nameiETP_ECO57
    AccessioniPrimary (citable) accession number: P0ACZ3
    Secondary accession number(s): P75880, Q8XC24
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 22, 2005
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3