P0ACU0 (YBIH_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized HTH-type transcriptional regulator YbiH

Gene names

Name:	ybiH
Ordered Locus Names:	b0796, JW0780

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 HTH tetR-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from sequence or structural similarity PubMed 10734204PubMed 15556475. Source: EcoCyc
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 223	223	Uncharacterized HTH-type transcriptional regulator YbiH		PRO_0000070632
Regions
	Domain	11 – 70	60	HTH tetR-type
	DNA binding	33 – 52	20	H-T-H motif Potential

Sequences

	Sequence		Length	Mass (Da)
	P0ACU0 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: B85EBC247EE8DA86	FASTA	223	25,017
	10 20 30 40 50 60 MNNPAMTIKG EQAKKQLIAA ALAQFGEYGM NATTREIAAQ AGQNIAAITY YFGSKEDLYL 70 80 90 100 110 120 ACAQWIADFI GEQFRPHAEE AERLFAQPQP DRAAIRELIL RACRNMIKLL TQDDTVNLSK 130 140 150 160 170 180 FISREQLSPT AAYHLVHEQV ISPLHSHLTR LIAAWTGCDA NDTRMILHTH ALIGEILAFR 190 200 210 220 LGKETILLRT GWTAFDEEKT ELINQTVTCH IDLILQGLSQ RSL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural analysis of the rhlE gene of Escherichia coli." Ohmori H. Jpn. J. Genet. 69:1-12(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-103. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L02123 Genomic DNA. No translation available. U00096 Genomic DNA. Translation: AAC73883.2. AP009048 Genomic DNA. Translation: BAA35456.1.
RefSeq	NP_415317.4. NC_000913.2. YP_489069.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P0ACU0.
SMR	P0ACU0. Positions 7-220.
ModBase	Search...
Protein-protein interaction databases
IntAct	P0ACU0. 8 interactions.
STRING	511145.b0796.
Proteomic databases
PRIDE	P0ACU0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC73883; AAC73883; b0796. BAA35456; BAA35456; BAA35456.
GeneID	12930967. 945421.
KEGG	ecj:Y75_p0769. eco:b0796.
PATRIC	32116793. VBIEscCol129921_0822.
Organism-specific databases
EchoBASE	EB2306.
EcoGene	EG12406. ybiH.
Phylogenomic databases
eggNOG	COG1309.
HOGENOM	HOG000118101.
OMA	QVIAPLH.
ProtClustDB	PRK11552.
Enzyme and pathway databases
BioCyc	EcoCyc:EG12406-MONOMER. ECOL316407:JW0780-MONOMER.
Gene expression databases
Genevestigator	P0ACU0.
Family and domain databases
Gene3D	1.10.10.60. 1 hit. 1.10.357.10. 1 hit.
InterPro	IPR023772. DNA-bd_HTH_TetR-type_CS. IPR009057. Homeodomain-like. IPR001647. HTH_TetR. IPR015893. Tet_transcr_reg_TetR-like_C. IPR011075. Tet_transcr_reg_TetR-rel_C. IPR015292. Tscrpt_reg_YbiH_C. [Graphical view]
Pfam	PF09209. DUF1956. 1 hit. PF00440. TetR_N. 1 hit. [Graphical view]
PRINTS	PR00455. HTHTETR.
SUPFAM	SSF46689. Homeodomain_like. 1 hit. SSF48498. TetR_like_C. 1 hit.
PROSITE	PS01081. HTH_TETR_1. 1 hit. PS50977. HTH_TETR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YBIH_ECOLI

Accession

Primary (citable) accession number: P0ACU0
Secondary accession number(s): P41037, P78054

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program