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Protein

HTH-type transcriptional regulator UidR

Gene

uidR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Repressor for the uidRABC (gusRABC) operon.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi33 – 52H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: EcoCyc

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G6867-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator UidR
Alternative name(s):
Gus operon repressor
Uid operon repressor
Gene namesi
Name:uidR
Synonyms:gusR
Ordered Locus Names:b1618, JW1610
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12667 uidR

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000706281 – 196HTH-type transcriptional regulator UidRAdd BLAST196

Proteomic databases

PaxDbiP0ACT6
PRIDEiP0ACT6

Interactioni

Protein-protein interaction databases

BioGridi4263484, 19 interactors
DIPiDIP-48053N
IntActiP0ACT6, 11 interactors
STRINGi316385.ECDH10B_1751

Structurei

3D structure databases

ProteinModelPortaliP0ACT6
SMRiP0ACT6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 70HTH tetR-typePROSITE-ProRule annotationAdd BLAST61

Phylogenomic databases

eggNOGiENOG4105XEA Bacteria
COG1309 LUCA
HOGENOMiHOG000215576
InParanoidiP0ACT6
KOiK16138
OMAiQTGMRDI
PhylomeDBiP0ACT6

Family and domain databases

InterProiView protein in InterPro
IPR023772 DNA-bd_HTH_TetR-type_CS
IPR009057 Homeobox-like_sf
IPR001647 HTH_TetR
IPR036271 Tet_transcr_reg_TetR-rel_C_sf
PfamiView protein in Pfam
PF00440 TetR_N, 1 hit
PRINTSiPR00455 HTHTETR
SUPFAMiSSF46689 SSF46689, 1 hit
SSF48498 SSF48498, 1 hit
PROSITEiView protein in PROSITE
PS01081 HTH_TETR_1, 1 hit
PS50977 HTH_TETR_2, 1 hit

Sequencei

Sequence statusi: Complete.

P0ACT6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMDNMQTEAQ PTRTRILNAA REIFSENGFH SASMKAICKS CAISPGTLYH
60 70 80 90 100
HFISKEALIQ AIILQDQERA LARFREPIEG IHFVDYMVES IVSLTHEAFG
110 120 130 140 150
QRALVVEIMA EGMRNPQVAA MLKNKHMTIT EFVAQRMRDA QQKGEISPDI
160 170 180 190
NTAMTSRLLL DLTYGVLADI EAEDLAREAS FAQGLRAMIG GILTAS
Length:196
Mass (Da):21,799
Last modified:November 22, 2005 - v1
Checksum:i22912EF7695268D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14641 Genomic DNA Translation: AAA68922.1
U00096 Genomic DNA Translation: AAC74690.1
AP009048 Genomic DNA Translation: BAA15369.1
PIRiD64918
RefSeqiNP_416135.1, NC_000913.3
WP_000969092.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74690; AAC74690; b1618
BAA15369; BAA15369; BAA15369
GeneIDi946150
KEGGiecj:JW1610
eco:b1618
PATRICifig|511145.12.peg.1689

Similar proteinsi

Entry informationi

Entry nameiUIDR_ECOLI
AccessioniPrimary (citable) accession number: P0ACT6
Secondary accession number(s): P76892, P76895, Q59431
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: March 28, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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