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P0ACS7 (RPIR_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
HTH-type transcriptional regulator RpiR
Alternative name(s):
Als operon repressor
Gene names
Name:rpiR
Synonyms:alsR, yjcY
Ordered Locus Names:b4089, JW4050
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length296 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Regulatory protein involved in rpiB gene repression. Also involved in als operon repression. Ref.5

Sequence similarities

Contains 1 HTH rpiR-type DNA-binding domain.

Contains 1 SIS domain.

Sequence caution

The sequence AAA96988.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 296296HTH-type transcriptional regulator RpiR
PRO_0000068620

Regions

Domain14 – 9077HTH rpiR-type
Domain134 – 274141SIS
DNA binding50 – 6920H-T-H motif Potential

Sequences

Sequence LengthMass (Da)Tools
P0ACS7 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 7946848F0798E200

FASTA29632,362
        10         20         30         40         50         60 
MSQSEFDSAL PNGIGLAPYL RMKQEGMTEN ESRIVEWLLK PGNLSCAPAI KDVAEALAVS 

        70         80         90        100        110        120 
EAMIVKVSKL LGFSGFRNLR SALEDYFSQS EQVLPSELAF DEAPQDVVNK VFNITLRTIM 

       130        140        150        160        170        180 
EGQSIVNVDE IHRAARFFYQ ARQRDLYGAG GSNAICADVQ HKFLRIGVRC QAYPDAHIMM 

       190        200        210        220        230        240 
MSASLLQEGD VVLVVTHSGR TSDVKAAVEL AKKNGAKIIC ITHSYHSPIA KLADYIICSP 

       250        260        270        280        290 
APETPLLGRN ASARILQLTL LDAFFVSVAQ LNIEQANINM QKTGAIVDFF SPGALK 

« Hide

References

« Hide 'large scale' references
[1]"Ribose catabolism of Escherichia coli: characterization of the rpiB gene encoding ribose phosphate isomerase B and of the rpiR gene, which is involved in regulation of rpiB expression."
Soerensen K.I., Hove-Jensen B.
J. Bacteriol. 178:1003-1011(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: K12.
[2]"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]"The D-allose operon of Escherichia coli K-12."
Kim C., Song S., Park C.
J. Bacteriol. 179:7631-7637(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION IN ALS REPRESSION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X82203 Genomic DNA. Translation: CAA57687.1.
U14003 Genomic DNA. Translation: AAA96988.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77050.2.
AP009048 Genomic DNA. Translation: BAE78092.1.
PIRS56317.
RefSeqNP_418513.4. NC_000913.3.
YP_492233.1. NC_007779.1.

3D structure databases

ProteinModelPortalP0ACS7.
SMRP0ACS7. Positions 20-287.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP0ACS7. 5 interactions.
STRING511145.b4089.

Proteomic databases

PRIDEP0ACS7.

Protocols and materials databases

DNASU948603.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC77050; AAC77050; b4089.
BAE78092; BAE78092; BAE78092.
GeneID12933688.
948603.
KEGGecj:Y75_p3977.
eco:b4089.
PATRIC32123735. VBIEscCol129921_4216.

Organism-specific databases

EchoBASEEB2353.
EcoGeneEG12459. rpiR.

Phylogenomic databases

eggNOGCOG1737.
HOGENOMHOG000027157.
OMANYAESPI.
OrthoDBEOG6HMXHM.
PhylomeDBP0ACS7.

Enzyme and pathway databases

BioCycEcoCyc:G7821-MONOMER.
ECOL316407:JW4050-MONOMER.
RETL1328306-WGS:GSTH-5049-MONOMER.

Gene expression databases

GenevestigatorP0ACS7.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
InterProIPR009057. Homeodomain-like.
IPR000281. HTH_RpiR.
IPR001347. SIS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF01418. HTH_6. 1 hit.
PF01380. SIS. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS51071. HTH_RPIR. 1 hit.
PS51464. SIS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP0ACS7.

Entry information

Entry nameRPIR_ECOLI
AccessionPrimary (citable) accession number: P0ACS7
Secondary accession number(s): P39266, P76791, Q2M6L4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: July 9, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene