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Protein

Uncharacterized HTH-type transcriptional regulator YfeR

Gene

yfeR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi20 – 39H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription, DNA-templated Source: GO_Central
  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7257-MONOMER.
ECOL316407:JW2400-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YfeR
Gene namesi
Name:yfeR
Ordered Locus Names:b2409, JW2400
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14159. yfeR.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001057911 – 308Uncharacterized HTH-type transcriptional regulator YfeRAdd BLAST308

Proteomic databases

PaxDbiP0ACR7.
PRIDEiP0ACR7.

Interactioni

Protein-protein interaction databases

BioGridi4261239. 25 interactors.
DIPiDIP-12017N.
IntActiP0ACR7. 2 interactors.
STRINGi511145.b2409.

Structurei

3D structure databases

ProteinModelPortaliP0ACR7.
SMRiP0ACR7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 60HTH lysR-typePROSITE-ProRule annotationAdd BLAST60

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108M0I. Bacteria.
ENOG410XQRQ. LUCA.
HOGENOMiHOG000233514.
InParanoidiP0ACR7.
OMAiIHRRDDK.
PhylomeDBiP0ACR7.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ACR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYSLKQLKV FVTVAQEKSF SRAGERIGLS QSAVSHSVKE LENHTGVRLL
60 70 80 90 100
DRTTREVVLT DAGQQLALRL ERLLDELNST LRDTGRMGQQ LSGKVRVAAS
110 120 130 140 150
QTISAHLIPQ CIAESHRRYP DIQFVLHDRP QQWVMESIRQ GDVDFGIVID
160 170 180 190 200
PGPVGDLQCE AILSEPFFLL CHRDSALAVE DYVPWQALQG AKLVLQDYAS
210 220 230 240 250
GSRPLIDAAL ARNGIQANIV QEIGHPATLF PMVAAGIGIS ILPALALPLP
260 270 280 290 300
EGSPLVVKRI TPVVERQLML VRRKNRSLST AAEALWDVVR DQGNALMAGR

EGDPLYQI
Length:308
Mass (Da):33,903
Last modified:November 22, 2005 - v1
Checksum:i23B6A771E4AB8587
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75462.1.
AP009048 Genomic DNA. Translation: BAA16280.1.
PIRiH65014.
RefSeqiNP_416904.1. NC_000913.3.
WP_001109794.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75462; AAC75462; b2409.
BAA16280; BAA16280; BAA16280.
GeneIDi946873.
KEGGiecj:JW2400.
eco:b2409.
PATRICi32120199. VBIEscCol129921_2502.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75462.1.
AP009048 Genomic DNA. Translation: BAA16280.1.
PIRiH65014.
RefSeqiNP_416904.1. NC_000913.3.
WP_001109794.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0ACR7.
SMRiP0ACR7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261239. 25 interactors.
DIPiDIP-12017N.
IntActiP0ACR7. 2 interactors.
STRINGi511145.b2409.

Proteomic databases

PaxDbiP0ACR7.
PRIDEiP0ACR7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75462; AAC75462; b2409.
BAA16280; BAA16280; BAA16280.
GeneIDi946873.
KEGGiecj:JW2400.
eco:b2409.
PATRICi32120199. VBIEscCol129921_2502.

Organism-specific databases

EchoBASEiEB3911.
EcoGeneiEG14159. yfeR.

Phylogenomic databases

eggNOGiENOG4108M0I. Bacteria.
ENOG410XQRQ. LUCA.
HOGENOMiHOG000233514.
InParanoidiP0ACR7.
OMAiIHRRDDK.
PhylomeDBiP0ACR7.

Enzyme and pathway databases

BioCyciEcoCyc:G7257-MONOMER.
ECOL316407:JW2400-MONOMER.

Miscellaneous databases

PROiP0ACR7.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYFER_ECOLI
AccessioniPrimary (citable) accession number: P0ACR7
Secondary accession number(s): P77500
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: November 2, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.