yeiE

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
DNA bindingⁱ	20 – 39	H-T-H motifPROSITE-ProRule annotationAdd BLAST		20

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-KW
DNA binding transcription factor activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

transcription, DNA-templated
Source: EcoCyc
Inferred from mutant phenotypeⁱ
- 12400704

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding
Biological process	Transcription, Transcription regulation

Enzyme and pathway databases

BioCycⁱ	EcoCyc:EG12105-MONOMER.

BioCycⁱ

EcoCyc:EG12105-MONOMER.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Uncharacterized HTH-type transcriptional regulator YeiE
Gene namesⁱ	Name:yeiE Ordered Locus Names:b2157, JW2144
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000318 Componentⁱ: Chromosome UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG12105. yeiE.

EcoGeneⁱ

EG12105. yeiE.

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000105788	1 – 293	Uncharacterized HTH-type transcriptional regulator YeiEAdd BLAST		293

Proteomic databases

PaxDbⁱ	P0ACR4.
PRIDEⁱ	P0ACR4.

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	4261800. 12 interactors.
Database of interacting proteins More...DIPⁱ	DIP-11918N.
STRINGⁱ	316385.ECDH10B_2314.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P0ACR4.
SMRⁱ	P0ACR4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1 – 60	HTH lysR-typePROSITE-ProRule annotationAdd BLAST		60

Phylogenomic databases

eggNOGⁱ	ENOG4105DUM. Bacteria. COG0583. LUCA.
HOGENOMⁱ	HOG000233518.
InParanoidⁱ	P0ACR4.
OMAⁱ	IEGPCHH.
PhylomeDBⁱ	P0ACR4.

Family and domain databases

Gene3Dⁱ	1.10.10.10. 1 hit.
InterProⁱ	View protein in InterPro IPR005119. LysR_subst-bd. IPR000847. Tscrpt_reg_HTH_LysR. IPR036388. WH-like_DNA-bd_sf. IPR036390. WH_DNA-bd_sf.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00126. HTH_1. 1 hit. PF03466. LysR_substrate. 1 hit.
PRINTSⁱ	PR00039. HTHLYSR.
SUPFAMⁱ	SSF46785. SSF46785. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50931. HTH_LYSR. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

P0ACR4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MHITLRQLEV FAEVLKSGST TQASVMLALS QSAVSAALTD LEGQLGVQLF 
        60         70         80         90        100
DRVGKRLVVN EHGRLLYPRA LALLEQAVEI EQLFREDNGA IRIYASSTIG 
       110        120        130        140        150
NYILPAVIAR YRHDYPQLPI ELSVGNSQDV MQAVLDFRVD IGFIEGPCHS 
       160        170        180        190        200
TEIISEPWLE DELVVFAAPT SPLARGPVTL EQLAAAPWIL RERGSGTREI 
       210        220        230        240        250
VDYLLLSHLP KFEMAMELGN SEAIKHAVRH GLGISCLSRR VIEDQLQAGT 
       260        270        280        290 
LSEVAVPLPR LMRTLWRIHH RQKHLSNALR RFLDYCDPAN VPR

Length:293

Mass (Da):32,724

Last modified:November 22, 2005 - v1

Checksum:ⁱ3AD5B7411C5A27D5

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U00007 Genomic DNA. Translation: AAA60508.1. M89774 Genomic DNA. Translation: AAA17052.1. U00096 Genomic DNA. Translation: AAC75218.1. AP009048 Genomic DNA. Translation: BAE76634.1.
PIRⁱ	D64984.
NCBI Reference Sequences More...RefSeqⁱ	NP_416662.1. NC_000913.3. WP_000548294.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAC75218; AAC75218; b2157. BAE76634; BAE76634; BAE76634.
GeneIDⁱ	946657.
KEGGⁱ	ecj:JW2144. eco:b2157.
PATRICⁱ	fig\|1411691.4.peg.82.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P0ACR4	P0ACR6 P0ACR5 A0A077ZKR4 A0A2I8JFE3 A0A024KWQ4 A0A222QMD8 W1BJC5 A0A2D0P607 A0A2H1BJU3 A0A1S6TCP5 +136	Escherichia coli O157:H7 Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) Trichuris trichiura (Whipworm) (Trichocephalus trichiurus) Shigella flexneri Escherichia coli D6-113.11 Escherichia coli NCCP15648 Klebsiella pneumoniae IS22 Escherichia coli O127:H6 Escherichia coli O55:H7 str. USDA 5905 Escherichia coli M8 And more	293	UniRef100_P0ACR6	Cluster: Uncharacterized HTH-type transcriptional regulator YeiE	147

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P0ACR4	P0ACR6 P0ACR5 A0A077ZKR4 A0A2I8JFE3 A0A024KWQ4 A0A222QMD8 W1BJC5 A0A2D0P607 A0A2H1BJU3 A0A1S6TCP5 +358	Escherichia coli O157:H7 Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) Trichuris trichiura (Whipworm) (Trichocephalus trichiurus) Shigella flexneri Escherichia coli D6-113.11 Escherichia coli NCCP15648 Klebsiella pneumoniae IS22 Escherichia coli O127:H6 Escherichia coli O55:H7 str. USDA 5905 Escherichia coli M8 And more	293	UniRef90_P0ACR6	Cluster: Uncharacterized HTH-type transcriptional regulator YeiE	369

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P0ACR4	P0ACR6 P0ACR5 A0A077ZKR4 A0A2I8JFE3 A0A024KWQ4 A0A222QMD8 W1BJC5 A0A2D0P607 A0A2H1BJU3 A0A1S6TCP5 +360	Escherichia coli O157:H7 Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) Trichuris trichiura (Whipworm) (Trichocephalus trichiurus) Shigella flexneri Escherichia coli D6-113.11 Escherichia coli NCCP15648 Klebsiella pneumoniae IS22 Escherichia coli O127:H6 Escherichia coli O55:H7 str. USDA 5905 Escherichia coli M8 And more	293	UniRef50_P0ACR6	Cluster: Uncharacterized HTH-type transcriptional regulator YeiE	371

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U00007 Genomic DNA. Translation: AAA60508.1. M89774 Genomic DNA. Translation: AAA17052.1. U00096 Genomic DNA. Translation: AAC75218.1. AP009048 Genomic DNA. Translation: BAE76634.1.
PIRⁱ	D64984.
NCBI Reference Sequences More...RefSeqⁱ	NP_416662.1. NC_000913.3. WP_000548294.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortalⁱ	P0ACR4.
SMRⁱ	P0ACR4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	4261800. 12 interactors.
Database of interacting proteins More...DIPⁱ	DIP-11918N.
STRINGⁱ	316385.ECDH10B_2314.

Proteomic databases

PaxDbⁱ	P0ACR4.
PRIDEⁱ	P0ACR4.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAC75218; AAC75218; b2157. BAE76634; BAE76634; BAE76634.
GeneIDⁱ	946657.
KEGGⁱ	ecj:JW2144. eco:b2157.
PATRICⁱ	fig\|1411691.4.peg.82.

Organism-specific databases

EchoBASEⁱ	EB2029.
EcoGeneⁱ	EG12105. yeiE.

Phylogenomic databases

eggNOGⁱ	ENOG4105DUM. Bacteria. COG0583. LUCA.
HOGENOMⁱ	HOG000233518.
InParanoidⁱ	P0ACR4.
OMAⁱ	IEGPCHH.
PhylomeDBⁱ	P0ACR4.

Enzyme and pathway databases

BioCycⁱ	EcoCyc:EG12105-MONOMER.

BioCycⁱ

EcoCyc:EG12105-MONOMER.

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P0ACR4.

PROⁱ

PR:P0ACR4.

Family and domain databases

Gene3Dⁱ	1.10.10.10. 1 hit.
InterProⁱ	View protein in InterPro IPR005119. LysR_subst-bd. IPR000847. Tscrpt_reg_HTH_LysR. IPR036388. WH-like_DNA-bd_sf. IPR036390. WH_DNA-bd_sf.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00126. HTH_1. 1 hit. PF03466. LysR_substrate. 1 hit.
PRINTSⁱ	PR00039. HTHLYSR.
SUPFAMⁱ	SSF46785. SSF46785. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50931. HTH_LYSR. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	YEIE_ECOLI
Accessionⁱ	P0ACR4Primary (citable) accession number: P0ACR4 Secondary accession number(s): P32484, Q2MAS2
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
	Last sequence update:	November 22, 2005
	Last modified:	March 28, 2018
	This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P0ACR4 (YEIE_ECOLI)

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Uncharacterized HTH-type transcriptional regulator YeiE

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ