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Protein

HTH-type transcriptional activator AllS

Gene

allS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Positive regulator essential for the expression of allD operon. Binds to the allD promoter.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi19 – 38H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

  • DNA binding transcription factor activity Source: EcoCyc
  • sequence-specific DNA binding Source: EcoCyc

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G6274-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator AllS
Gene namesi
Name:allS
Synonyms:glxA1, ybbS
Ordered Locus Names:b0504, JW0492
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13267 allS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001057761 – 308HTH-type transcriptional activator AllSAdd BLAST308

Proteomic databases

PaxDbiP0ACR0
PRIDEiP0ACR0

Expressioni

Inductioni

Induced anaerobically and by nitrogen limitation. Repressed by AllR.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4259497, 7 interactors
IntActiP0ACR0, 4 interactors
STRINGi316385.ECDH10B_0460

Structurei

3D structure databases

ProteinModelPortaliP0ACR0
SMRiP0ACR0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 59HTH lysR-typePROSITE-ProRule annotationAdd BLAST58

Phylogenomic databases

eggNOGiENOG4107653 Bacteria
ENOG410XWA5 LUCA
HOGENOMiHOG000181312
InParanoidiP0ACR0
KOiK10972
OMAiVYMGVWD
PhylomeDBiP0ACR0

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR005119 LysR_subst-bd
IPR000847 Tscrpt_reg_HTH_LysR
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00126 HTH_1, 1 hit
PF03466 LysR_substrate, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50931 HTH_LYSR, 1 hit

Sequencei

Sequence statusi: Complete.

P0ACR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDPETLRTF IAVAETGSFS KAAERLCKTT ATISYRIKLL EENTGVALFF
60 70 80 90 100
RTTRSVTLTA AGEHLLSQAR DWLSWLESMP SELQQVNDGV ERQVNIVINN
110 120 130 140 150
LLYNPQAVAQ LLAWLNERYP FTQFHISRQI YMGVWDSLLY EGFSLAIGVT
160 170 180 190 200
GTEALANTFS LDPLGSVQWR FVMAADHPLA NVEEPLTEAQ LRRFPAVNIE
210 220 230 240 250
DSARTLTKRV AWRLPGQKEI IVPDMETKIA AHLAGVGIGF LPKSLCQSMI
260 270 280 290 300
DNQQLVSRVI PTMRPPSPLS LAWRKFGSGK AVEDIVTLFT QRRPEISGFL

EIFGNPRS
Length:308
Mass (Da):34,512
Last modified:November 22, 2005 - v1
Checksum:i42A4727F078CE0B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89024 Genomic DNA Translation: AAB93845.1
U82664 Genomic DNA Translation: AAB40257.1
U00096 Genomic DNA Translation: AAC73606.1
AP009048 Genomic DNA Translation: BAE76282.1
PIRiG64781
RefSeqiNP_415037.1, NC_000913.3
WP_000460145.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73606; AAC73606; b0504
BAE76282; BAE76282; BAE76282
GeneIDi945139
KEGGiecj:JW0492
eco:b0504
PATRICifig|1411691.4.peg.1773

Similar proteinsi

Entry informationi

Entry nameiALLS_ECOLI
AccessioniPrimary (citable) accession number: P0ACR0
Secondary accession number(s): P77702, Q2MBS4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: March 28, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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