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Protein

HTH-type transcriptional activator AllS

Gene

allS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Positive regulator essential for the expression of allD operon. Binds to the allD promoter.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi19 – 3820H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • sequence-specific DNA binding Source: EcoCyc
  • transcription factor activity, sequence-specific DNA binding Source: EcoCyc

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6274-MONOMER.
ECOL316407:JW0492-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator AllS
Gene namesi
Name:allS
Synonyms:glxA1, ybbS
Ordered Locus Names:b0504, JW0492
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13267. allS.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308HTH-type transcriptional activator AllSPRO_0000105776Add
BLAST

Proteomic databases

PaxDbiP0ACR0.

Expressioni

Inductioni

Induced anaerobically and by nitrogen limitation. Repressed by AllR.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4259497. 7 interactions.
IntActiP0ACR0. 4 interactions.
STRINGi511145.b0504.

Structurei

3D structure databases

ProteinModelPortaliP0ACR0.
SMRiP0ACR0. Positions 2-295.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 5958HTH lysR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4107653. Bacteria.
ENOG410XWA5. LUCA.
HOGENOMiHOG000181312.
InParanoidiP0ACR0.
KOiK10972.
OMAiVYMGVWD.
PhylomeDBiP0ACR0.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ACR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDPETLRTF IAVAETGSFS KAAERLCKTT ATISYRIKLL EENTGVALFF
60 70 80 90 100
RTTRSVTLTA AGEHLLSQAR DWLSWLESMP SELQQVNDGV ERQVNIVINN
110 120 130 140 150
LLYNPQAVAQ LLAWLNERYP FTQFHISRQI YMGVWDSLLY EGFSLAIGVT
160 170 180 190 200
GTEALANTFS LDPLGSVQWR FVMAADHPLA NVEEPLTEAQ LRRFPAVNIE
210 220 230 240 250
DSARTLTKRV AWRLPGQKEI IVPDMETKIA AHLAGVGIGF LPKSLCQSMI
260 270 280 290 300
DNQQLVSRVI PTMRPPSPLS LAWRKFGSGK AVEDIVTLFT QRRPEISGFL

EIFGNPRS
Length:308
Mass (Da):34,512
Last modified:November 22, 2005 - v1
Checksum:i42A4727F078CE0B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89024 Genomic DNA. Translation: AAB93845.1.
U82664 Genomic DNA. Translation: AAB40257.1.
U00096 Genomic DNA. Translation: AAC73606.1.
AP009048 Genomic DNA. Translation: BAE76282.1.
PIRiG64781.
RefSeqiNP_415037.1. NC_000913.3.
WP_000460145.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73606; AAC73606; b0504.
BAE76282; BAE76282; BAE76282.
GeneIDi945139.
KEGGiecj:JW0492.
eco:b0504.
PATRICi32116167. VBIEscCol129921_0525.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89024 Genomic DNA. Translation: AAB93845.1.
U82664 Genomic DNA. Translation: AAB40257.1.
U00096 Genomic DNA. Translation: AAC73606.1.
AP009048 Genomic DNA. Translation: BAE76282.1.
PIRiG64781.
RefSeqiNP_415037.1. NC_000913.3.
WP_000460145.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0ACR0.
SMRiP0ACR0. Positions 2-295.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259497. 7 interactions.
IntActiP0ACR0. 4 interactions.
STRINGi511145.b0504.

Proteomic databases

PaxDbiP0ACR0.

Protocols and materials databases

DNASUi945139.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73606; AAC73606; b0504.
BAE76282; BAE76282; BAE76282.
GeneIDi945139.
KEGGiecj:JW0492.
eco:b0504.
PATRICi32116167. VBIEscCol129921_0525.

Organism-specific databases

EchoBASEiEB3053.
EcoGeneiEG13267. allS.

Phylogenomic databases

eggNOGiENOG4107653. Bacteria.
ENOG410XWA5. LUCA.
HOGENOMiHOG000181312.
InParanoidiP0ACR0.
KOiK10972.
OMAiVYMGVWD.
PhylomeDBiP0ACR0.

Enzyme and pathway databases

BioCyciEcoCyc:G6274-MONOMER.
ECOL316407:JW0492-MONOMER.

Miscellaneous databases

PROiP0ACR0.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiALLS_ECOLI
AccessioniPrimary (citable) accession number: P0ACR0
Secondary accession number(s): P77702, Q2MBS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: September 7, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.