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Protein

Uncharacterized HTH-type transcriptional regulator YtfH

Gene

ytfH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7869-MONOMER.
ECOL316407:JW5747-MONOMER.
RETL1328306-WGS:GSTH-2617-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YtfH
Gene namesi
Name:ytfH
Ordered Locus Names:b4212, JW5747
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12508. ytfH.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 126126Uncharacterized HTH-type transcriptional regulator YtfHPRO_0000148881Add
BLAST

Proteomic databases

EPDiP0ACN2.
PaxDbiP0ACN2.
PRIDEiP0ACN2.

Interactioni

Protein-protein interaction databases

BioGridi4263389. 9 interactions.
DIPiDIP-12936N.
STRINGi511145.b4212.

Structurei

3D structure databases

ProteinModelPortaliP0ACN2.
SMRiP0ACN2. Positions 12-122.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 11899HTH hxlR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH hxlR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105KVH. Bacteria.
COG1733. LUCA.
HOGENOMiHOG000293549.
InParanoidiP0ACN2.
OMAiQILQHLT.
OrthoDBiEOG622PS8.
PhylomeDBiP0ACN2.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR002577. HTH_HxlR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01638. HxlR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS51118. HTH_HXLR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ACN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQVSLSQQL KEGNLFAEQC PSREVLKHVT SRWGVLILVA LREGTHRFSD
60 70 80 90 100
LRRKIGGVSE KMLAQSLQAL EQDGFLNRIA YPVVPPHVEY SLTPLGEQVS
110 120
EKVAALADWI ELNLPEVLAV RDERAA
Length:126
Mass (Da):14,075
Last modified:November 22, 2005 - v1
Checksum:i43448B2D88593FDB
GO

Sequence cautioni

The sequence AAA97108.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97108.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77169.2.
AP009048 Genomic DNA. Translation: BAE78213.1.
PIRiS56437.
RefSeqiNP_418633.4. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC77169; AAC77169; b4212.
BAE78213; BAE78213; BAE78213.
GeneIDi948730.
KEGGiecj:JW5747.
eco:b4212.
PATRICi32123999. VBIEscCol129921_4344.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97108.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77169.2.
AP009048 Genomic DNA. Translation: BAE78213.1.
PIRiS56437.
RefSeqiNP_418633.4. NC_000913.3.

3D structure databases

ProteinModelPortaliP0ACN2.
SMRiP0ACN2. Positions 12-122.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263389. 9 interactions.
DIPiDIP-12936N.
STRINGi511145.b4212.

Proteomic databases

EPDiP0ACN2.
PaxDbiP0ACN2.
PRIDEiP0ACN2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77169; AAC77169; b4212.
BAE78213; BAE78213; BAE78213.
GeneIDi948730.
KEGGiecj:JW5747.
eco:b4212.
PATRICi32123999. VBIEscCol129921_4344.

Organism-specific databases

EchoBASEiEB2401.
EcoGeneiEG12508. ytfH.

Phylogenomic databases

eggNOGiENOG4105KVH. Bacteria.
COG1733. LUCA.
HOGENOMiHOG000293549.
InParanoidiP0ACN2.
OMAiQILQHLT.
OrthoDBiEOG622PS8.
PhylomeDBiP0ACN2.

Enzyme and pathway databases

BioCyciEcoCyc:G7869-MONOMER.
ECOL316407:JW5747-MONOMER.
RETL1328306-WGS:GSTH-2617-MONOMER.

Miscellaneous databases

PROiP0ACN2.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR002577. HTH_HxlR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01638. HxlR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS51118. HTH_HXLR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
    Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
    Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYTFH_ECOLI
AccessioniPrimary (citable) accession number: P0ACN2
Secondary accession number(s): P39316, Q2M693
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: March 16, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.