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P0ACM5

- YEGW_ECOLI

UniProt

P0ACM5 - YEGW_ECOLI

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Protein

Uncharacterized HTH-type transcriptional regulator YegW

Gene

yegW

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi50 – 6920H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7133-MONOMER.
ECOL316407:JW2088-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YegW
Gene namesi
Name:yegW
Ordered Locus Names:b2101, JW2088
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG14066. yegW.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 248248Uncharacterized HTH-type transcriptional regulator YegWPRO_0000050676Add
BLAST

Proteomic databases

PRIDEiP0ACM5.

Expressioni

Gene expression databases

GenevestigatoriP0ACM5.

Interactioni

Protein-protein interaction databases

DIPiDIP-11893N.
IntActiP0ACM5. 2 interactions.
STRINGi511145.b2101.

Structurei

3D structure databases

ProteinModelPortaliP0ACM5.
SMRiP0ACM5. Positions 23-245.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini22 – 9069HTH gntR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH gntR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG2188.
HOGENOMiHOG000228717.
InParanoidiP0ACM5.
OMAiPIEYNLG.
OrthoDBiEOG689HVZ.
PhylomeDBiP0ACM5.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.40.1410.10. 1 hit.
InterProiIPR028978. Chorismate_lyase_/UTRA_dom.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011663. UTRA.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00392. GntR. 1 hit.
PF07702. UTRA. 1 hit.
[Graphical view]
PRINTSiPR00035. HTHGNTR.
SMARTiSM00345. HTH_GNTR. 1 hit.
SM00866. UTRA. 1 hit.
[Graphical view]
SUPFAMiSSF64288. SSF64288. 1 hit.
PROSITEiPS50949. HTH_GNTR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ACM5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEQAHTQLIA QLNERILAAD NTPLYIKFAE TVKNAVRSGV LEHGNILPGE
60 70 80 90 100
RDLSQLTGVS RITVRKAMQA LEEEGVVTRS RGYGTQINNI FEYSLKEARG
110 120 130 140 150
FSQQVVLRGK KPDTLWVNKR VVKCPEEVAQ QLAVEAGSDV FLLKRIRYVD
160 170 180 190 200
EEAVSIEESW VPAHLIHDVD AIGISLYDYF RSQHIYPQRT RSRVSARMPD
210 220 230 240
AEFQSHIQLD SKIPVLVIKQ VALDQQQRPI EYSISHCRSD LYVFVCEE
Length:248
Mass (Da):28,277
Last modified:November 22, 2005 - v1
Checksum:iE4B3CD729CA7F1C8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC75162.1.
AP009048 Genomic DNA. Translation: BAA15969.1.
PIRiD64977.
RefSeqiNP_416604.1. NC_000913.3.
YP_490341.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC75162; AAC75162; b2101.
BAA15969; BAA15969; BAA15969.
GeneIDi12932167.
946639.
KEGGiecj:Y75_p2063.
eco:b2101.
PATRICi32119535. VBIEscCol129921_2178.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC75162.1 .
AP009048 Genomic DNA. Translation: BAA15969.1 .
PIRi D64977.
RefSeqi NP_416604.1. NC_000913.3.
YP_490341.1. NC_007779.1.

3D structure databases

ProteinModelPortali P0ACM5.
SMRi P0ACM5. Positions 23-245.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-11893N.
IntActi P0ACM5. 2 interactions.
STRINGi 511145.b2101.

Proteomic databases

PRIDEi P0ACM5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC75162 ; AAC75162 ; b2101 .
BAA15969 ; BAA15969 ; BAA15969 .
GeneIDi 12932167.
946639.
KEGGi ecj:Y75_p2063.
eco:b2101.
PATRICi 32119535. VBIEscCol129921_2178.

Organism-specific databases

EchoBASEi EB3819.
EcoGenei EG14066. yegW.

Phylogenomic databases

eggNOGi COG2188.
HOGENOMi HOG000228717.
InParanoidi P0ACM5.
OMAi PIEYNLG.
OrthoDBi EOG689HVZ.
PhylomeDBi P0ACM5.

Enzyme and pathway databases

BioCyci EcoCyc:G7133-MONOMER.
ECOL316407:JW2088-MONOMER.

Miscellaneous databases

PROi P0ACM5.

Gene expression databases

Genevestigatori P0ACM5.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
3.40.1410.10. 1 hit.
InterProi IPR028978. Chorismate_lyase_/UTRA_dom.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011663. UTRA.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00392. GntR. 1 hit.
PF07702. UTRA. 1 hit.
[Graphical view ]
PRINTSi PR00035. HTHGNTR.
SMARTi SM00345. HTH_GNTR. 1 hit.
SM00866. UTRA. 1 hit.
[Graphical view ]
SUPFAMi SSF64288. SSF64288. 1 hit.
PROSITEi PS50949. HTH_GNTR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYEGW_ECOLI
AccessioniPrimary (citable) accession number: P0ACM5
Secondary accession number(s): O08014, P76420
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3