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Protein

HTH-type transcriptional repressor RspR

Gene

rspR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi38 – 57H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

  • DNA binding Source: EcoCyc
  • DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  • transcription, DNA-templated Source: EcoCyc

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G6814-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional repressor RspR
Gene namesi
Name:rspRImported
Synonyms:ydfH
Ordered Locus Names:b1540, JW1533
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13820 rspR

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000506721 – 228HTH-type transcriptional repressor RspRAdd BLAST228

Proteomic databases

PaxDbiP0ACM2
PRIDEiP0ACM2

Interactioni

Protein-protein interaction databases

BioGridi4261737, 22 interactors
IntActiP0ACM2, 2 interactors
STRINGi316385.ECDH10B_1671

Structurei

3D structure databases

ProteinModelPortaliP0ACM2
SMRiP0ACM2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 78HTH gntR-typePROSITE-ProRule annotationAdd BLAST68

Phylogenomic databases

eggNOGiENOG4107XBN Bacteria
COG1802 LUCA
HOGENOMiHOG000273994
InParanoidiP0ACM2
KOiK22293
OMAiKLNRHNS
PhylomeDBiP0ACM2

Family and domain databases

CDDicd07377 WHTH_GntR, 1 hit
Gene3Di1.10.10.10, 1 hit
1.20.120.530, 1 hit
InterProiView protein in InterPro
IPR011711 GntR_C
IPR008920 TF_FadR/GntR_C
IPR000524 Tscrpt_reg_HTH_GntR
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF07729 FCD, 1 hit
PF00392 GntR, 1 hit
PRINTSiPR00035 HTHGNTR
SMARTiView protein in SMART
SM00895 FCD, 1 hit
SM00345 HTH_GNTR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF48008 SSF48008, 1 hit
PROSITEiView protein in PROSITE
PS50949 HTH_GNTR, 1 hit

Sequencei

Sequence statusi: Complete.

P0ACM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVETQLNPT QPVNQQIYRI LRRDIVHCLI APGTPLSEKE VSVRFNVSRQ
60 70 80 90 100
PVREAFIKLA ENGLIQIRPQ RGSYVNKISM AQVRNGSFIR QAIECAVARR
110 120 130 140 150
AASMITESQC YQLEQNLHQQ RIAIERKQLD DFFELDDNFH QLLTQIADCQ
160 170 180 190 200
LAWDTIENLK ATVDRVRYMS FDHVSPPEML LRQHLDIFSA LQKRDGDAVE
210 220
RAMTQHLQEI SESVRQIRQE NSDWFSEE
Length:228
Mass (Da):26,565
Last modified:November 22, 2005 - v1
Checksum:i8CFF8EB3BCF9AF84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74613.1
AP009048 Genomic DNA Translation: BAA15242.1
PIRiG64908
RefSeqiNP_416058.1, NC_000913.3
WP_000215549.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74613; AAC74613; b1540
BAA15242; BAA15242; BAA15242
GeneIDi946087
KEGGiecj:JW1533
eco:b1540
PATRICifig|511145.12.peg.1610

Similar proteinsi

Entry informationi

Entry nameiRSPR_ECOLI
AccessioniPrimary (citable) accession number: P0ACM2
Secondary accession number(s): P77577, Q83L25
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

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