Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

L-fucose operon activator

Gene

fucR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcriptional activator of the fuc operon.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi19 – 38H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Carbohydrate metabolism, Fucose metabolism, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:PD00444.
ECOL316407:JW2776-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
L-fucose operon activator
Gene namesi
Name:fucR
Ordered Locus Names:b2805, JW2776
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10353. fucR.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000502471 – 243L-fucose operon activatorAdd BLAST243

Proteomic databases

PaxDbiP0ACK8.
PRIDEiP0ACK8.

Interactioni

Protein-protein interaction databases

BioGridi4263538. 13 interactors.
IntActiP0ACK8. 5 interactors.
STRINGi511145.b2805.

Structurei

3D structure databases

ProteinModelPortaliP0ACK8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 57HTH deoR-typePROSITE-ProRule annotationAdd BLAST57

Sequence similaritiesi

Contains 1 HTH deoR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4107EDW. Bacteria.
COG1349. LUCA.
HOGENOMiHOG000224683.
KOiK02430.
OMAiPICHEMA.
PhylomeDBiP0ACK8.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR014036. DeoR_C.
IPR001034. DeoR_HTH.
IPR018356. Tscrpt_reg_HTH_DeoR_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00455. DeoRC. 1 hit.
PF08220. HTH_DeoR. 1 hit.
[Graphical view]
PRINTSiPR00037. HTHLACR.
SMARTiSM00420. HTH_DEOR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00894. HTH_DEOR_1. 1 hit.
PS51000. HTH_DEOR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ACK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAARQQAIV DLLLNHTSLT TEALSEQLKV SKETIRRDLN ELQTQGKILR
60 70 80 90 100
NHGRAKYIHR QNQDSGDPFH IRLKSHYAHK ADIAREALAW IEEGMVIALD
110 120 130 140 150
ASSTCWYLAR QLPDINIQVF TNSHPICHEL GKRERIQLIS SGGTLERKYG
160 170 180 190 200
CYVNPSLISQ LKSLEIDLFI FSCEGIDSSG ALWDSNAINA DYKSMLLKRA
210 220 230 240
AQSLLLIDKS KFNRSGEARI GHLDEVTHII SDERQVATSL VTA
Length:243
Mass (Da):27,362
Last modified:November 22, 2005 - v1
Checksum:i3DFBBD33E7E64296
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15025 Genomic DNA. Translation: CAA33130.1.
U29581 Genomic DNA. Translation: AAB40455.1.
U00096 Genomic DNA. Translation: AAC75847.1.
AP009048 Genomic DNA. Translation: BAE76877.1.
PIRiJS0188. RGECFO.
RefSeqiNP_417285.1. NC_000913.3.
WP_000642344.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75847; AAC75847; b2805.
BAE76877; BAE76877; BAE76877.
GeneIDi946905.
KEGGiecj:JW2776.
eco:b2805.
PATRICi32121026. VBIEscCol129921_2905.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15025 Genomic DNA. Translation: CAA33130.1.
U29581 Genomic DNA. Translation: AAB40455.1.
U00096 Genomic DNA. Translation: AAC75847.1.
AP009048 Genomic DNA. Translation: BAE76877.1.
PIRiJS0188. RGECFO.
RefSeqiNP_417285.1. NC_000913.3.
WP_000642344.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0ACK8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263538. 13 interactors.
IntActiP0ACK8. 5 interactors.
STRINGi511145.b2805.

Proteomic databases

PaxDbiP0ACK8.
PRIDEiP0ACK8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75847; AAC75847; b2805.
BAE76877; BAE76877; BAE76877.
GeneIDi946905.
KEGGiecj:JW2776.
eco:b2805.
PATRICi32121026. VBIEscCol129921_2905.

Organism-specific databases

EchoBASEiEB0349.
EcoGeneiEG10353. fucR.

Phylogenomic databases

eggNOGiENOG4107EDW. Bacteria.
COG1349. LUCA.
HOGENOMiHOG000224683.
KOiK02430.
OMAiPICHEMA.
PhylomeDBiP0ACK8.

Enzyme and pathway databases

BioCyciEcoCyc:PD00444.
ECOL316407:JW2776-MONOMER.

Miscellaneous databases

PROiP0ACK8.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR014036. DeoR_C.
IPR001034. DeoR_HTH.
IPR018356. Tscrpt_reg_HTH_DeoR_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00455. DeoRC. 1 hit.
PF08220. HTH_DeoR. 1 hit.
[Graphical view]
PRINTSiPR00037. HTHLACR.
SMARTiSM00420. HTH_DEOR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00894. HTH_DEOR_1. 1 hit.
PS51000. HTH_DEOR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFUCR_ECOLI
AccessioniPrimary (citable) accession number: P0ACK8
Secondary accession number(s): P11554, Q2MA29
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: November 2, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.