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Protein

Right origin-binding protein

Gene

rob

Organism
Shigella flexneri
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds to the right arm of the replication origin oriC of the chromosome. Rob binding may influence the formation of the nucleoprotein structure, required for oriC function in the initiation of replication (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi24 – 43H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Right origin-binding protein
Gene namesi
Name:rob
Ordered Locus Names:SF4428, S4699
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001945801 – 289Right origin-binding proteinAdd BLAST289

Proteomic databases

PaxDbiP0ACI2.
PRIDEiP0ACI2.

Interactioni

Protein-protein interaction databases

STRINGi198214.SF4428.

Structurei

3D structure databases

ProteinModelPortaliP0ACI2.
SMRiP0ACI2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105UEI. Bacteria.
COG2207. LUCA.
HOGENOMiHOG000127886.
KOiK05804.
OMAiWCATGIC.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
3.20.80.10. 1 hit.
InterProiIPR010499. AraC_E-bd.
IPR029442. GyrI-like.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR011256. Reg_factor_effector_dom.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF06445. GyrI-like. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00871. AraC_E_bind. 1 hit.
SM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF55136. SSF55136. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ACI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDQAGIIRDL LIWLEGHLDQ PLSLDNVAAK AGYSKWHLQR MFKDVTGHAI
60 70 80 90 100
GAYIRARRLS KSAVALRLTA RPILDIALQY RFDSQQTFTR AFKKQFAQTP
110 120 130 140 150
ALYRRSPEWS AFGIRPPLRL GEFTMPEHKF VTLEDTPLIG VTQSYSCSLE
160 170 180 190 200
QISDFRHEMR YQFWHDFLGN APTIPPVLYG LNETRPSQDK DDEQEVFYTT
210 220 230 240 250
ALAQDQADGY VLTGHPVMLQ GGEYVMFTYE GLGTGVQEFI LTVYGTCMPM
260 270 280
LNLTRRKGQD IERYYPAEDA KAGDRPINLR CELLIPIRR
Length:289
Mass (Da):33,145
Last modified:November 22, 2005 - v1
Checksum:i4436B1A04BE86A93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN45841.1.
AE014073 Genomic DNA. Translation: AAP19615.1.
RefSeqiNP_710134.1. NC_004337.2.
WP_000371666.1. NZ_LVJC01000018.1.

Genome annotation databases

EnsemblBacteriaiAAN45841; AAN45841; SF4428.
AAP19615; AAP19615; S4699.
GeneIDi1027496.
KEGGisfl:SF4428.
sft:NCTC1_04809.
sfx:S4699.
PATRICi18711466. VBIShiFle31049_5128.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN45841.1.
AE014073 Genomic DNA. Translation: AAP19615.1.
RefSeqiNP_710134.1. NC_004337.2.
WP_000371666.1. NZ_LVJC01000018.1.

3D structure databases

ProteinModelPortaliP0ACI2.
SMRiP0ACI2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198214.SF4428.

Proteomic databases

PaxDbiP0ACI2.
PRIDEiP0ACI2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN45841; AAN45841; SF4428.
AAP19615; AAP19615; S4699.
GeneIDi1027496.
KEGGisfl:SF4428.
sft:NCTC1_04809.
sfx:S4699.
PATRICi18711466. VBIShiFle31049_5128.

Phylogenomic databases

eggNOGiENOG4105UEI. Bacteria.
COG2207. LUCA.
HOGENOMiHOG000127886.
KOiK05804.
OMAiWCATGIC.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
3.20.80.10. 1 hit.
InterProiIPR010499. AraC_E-bd.
IPR029442. GyrI-like.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR011256. Reg_factor_effector_dom.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF06445. GyrI-like. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00871. AraC_E_bind. 1 hit.
SM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF55136. SSF55136. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiROB_SHIFL
AccessioniPrimary (citable) accession number: P0ACI2
Secondary accession number(s): P27292
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: November 2, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.