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Protein

Putative colanic acid biosynthesis acetyltransferase WcaB

Gene

wcaB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Pathwayi: slime polysaccharide biosynthesis

This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.
View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.

GO - Molecular functioni

  • acetyltransferase activity Source: EcoliWiki
  • serine O-acetyltransferase activity Source: InterPro

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:G7103-MONOMER.
ECOL316407:JW2043-MONOMER.
UniPathwayiUPA00936.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative colanic acid biosynthesis acetyltransferase WcaB (EC:2.3.1.-)
Gene namesi
Name:wcaB
Ordered Locus Names:b2058, JW2043
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13570. wcaB.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 162162Putative colanic acid biosynthesis acetyltransferase WcaBPRO_0000068733Add
BLAST

Proteomic databases

PaxDbiP0ACC9.

Interactioni

Protein-protein interaction databases

BioGridi4260674. 269 interactions.
DIPiDIP-48109N.
IntActiP0ACC9. 1 interaction.
MINTiMINT-1267537.
STRINGi511145.b2058.

Structurei

3D structure databases

ProteinModelPortaliP0ACC9.
SMRiP0ACC9. Positions 20-158.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG41068PY. Bacteria.
COG1045. LUCA.
HOGENOMiHOG000049432.
InParanoidiP0ACC9.
KOiK03819.
OMAiLRHGVTI.
OrthoDBiEOG6HMXK6.
PhylomeDBiP0ACC9.

Family and domain databases

InterProiIPR024027. Colanic_acid_synth_WcaB.
IPR001451. Hexapep.
IPR018357. Hexapep_transf_CS.
IPR005881. Ser_O-AcTrfase.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00132. Hexapep. 1 hit.
[Graphical view]
PIRSFiPIRSF000441. CysE. 1 hit.
SUPFAMiSSF51161. SSF51161. 1 hit.
TIGRFAMsiTIGR04016. WcaB. 1 hit.
PROSITEiPS00101. HEXAPEP_TRANSFERASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ACC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEDLRANSW SLRPCCMVLA YRVAHFCSVW RKKNVLNNLW AAPLLVLYRI
60 70 80 90 100
ITECFFGYEI QAAATIGRRF TIHHGYAVVI NKNVVAGDDF TIRHGVTIGN
110 120 130 140 150
RGADNMACPH IGNGVELGAN VIILGDITLG NNVTVGAGSV VLDSVPDNAL
160
VVGEKARVKV IK
Length:162
Mass (Da):17,616
Last modified:November 8, 2005 - v1
Checksum:iF2462F836F3FB3AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA. Translation: AAC77837.1.
U00096 Genomic DNA. Translation: AAC75119.1.
AP009048 Genomic DNA. Translation: BAA15911.1.
PIRiA64972.
RefSeqiNP_416562.1. NC_000913.3.
WP_000888740.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75119; AAC75119; b2058.
BAA15911; BAA15911; BAA15911.
GeneIDi946573.
KEGGiecj:JW2043.
eco:b2058.
PATRICi32119449. VBIEscCol129921_2135.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA. Translation: AAC77837.1.
U00096 Genomic DNA. Translation: AAC75119.1.
AP009048 Genomic DNA. Translation: BAA15911.1.
PIRiA64972.
RefSeqiNP_416562.1. NC_000913.3.
WP_000888740.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0ACC9.
SMRiP0ACC9. Positions 20-158.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260674. 269 interactions.
DIPiDIP-48109N.
IntActiP0ACC9. 1 interaction.
MINTiMINT-1267537.
STRINGi511145.b2058.

Proteomic databases

PaxDbiP0ACC9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75119; AAC75119; b2058.
BAA15911; BAA15911; BAA15911.
GeneIDi946573.
KEGGiecj:JW2043.
eco:b2058.
PATRICi32119449. VBIEscCol129921_2135.

Organism-specific databases

EchoBASEiEB3340.
EcoGeneiEG13570. wcaB.

Phylogenomic databases

eggNOGiENOG41068PY. Bacteria.
COG1045. LUCA.
HOGENOMiHOG000049432.
InParanoidiP0ACC9.
KOiK03819.
OMAiLRHGVTI.
OrthoDBiEOG6HMXK6.
PhylomeDBiP0ACC9.

Enzyme and pathway databases

UniPathwayiUPA00936.
BioCyciEcoCyc:G7103-MONOMER.
ECOL316407:JW2043-MONOMER.

Miscellaneous databases

PROiP0ACC9.

Family and domain databases

InterProiIPR024027. Colanic_acid_synth_WcaB.
IPR001451. Hexapep.
IPR018357. Hexapep_transf_CS.
IPR005881. Ser_O-AcTrfase.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00132. Hexapep. 1 hit.
[Graphical view]
PIRSFiPIRSF000441. CysE. 1 hit.
SUPFAMiSSF51161. SSF51161. 1 hit.
TIGRFAMsiTIGR04016. WcaB. 1 hit.
PROSITEiPS00101. HEXAPEP_TRANSFERASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid."
    Stevenson G., Andrianopoulos K., Hobbs M., Reeves P.R.
    J. Bacteriol. 178:4885-4893(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiWCAB_ECOLI
AccessioniPrimary (citable) accession number: P0ACC9
Secondary accession number(s): P77558
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: January 20, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.