Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein GnsA

Gene

gnsA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.1 Publication

GO - Molecular functioni

  • identical protein binding Source: IntAct

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-1701.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein GnsA
Gene namesi
Name:gnsA
Synonyms:yccL
Ordered Locus Names:b4517, JW0976
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13233. gnsA.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002017221 – 57Protein GnsAAdd BLAST57

Proteomic databases

PaxDbiP0AC92.
PRIDEiP0AC92.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself2EBI-1121356,EBI-1121356

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

BioGridi4262837. 14 interactors.
IntActiP0AC92. 9 interactors.
STRINGi316385.ECDH10B_1063.

Structurei

Secondary structure

157
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 29Combined sources27
Beta strandi30 – 43Combined sources14
Beta strandi46 – 57Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4XO1X-ray1.80A1-57[»]
4XO2X-ray1.95A/B1-57[»]
ProteinModelPortaliP0AC92.
SMRiP0AC92.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the gns family.Curated

Phylogenomic databases

eggNOGiENOG4106H71. Bacteria.
ENOG410Y8R8. LUCA.
HOGENOMiHOG000268050.

Family and domain databases

InterProiView protein in InterPro
IPR012563. Gns.
PfamiView protein in Pfam
PF08178. GnsAB_toxin. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AC92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIEELKKQA ETEIADFIAQ KIAELNKNTG KEVSEIRFTA REKMTGLESY

DVKIKIM
Length:57
Mass (Da):6,576
Last modified:November 8, 2005 - v1
Checksum:i7BD48340D6D2966C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38541 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: ABD18647.1.
AP009048 Genomic DNA. Translation: BAA35758.1.
RefSeqiWP_001019197.1. NZ_LN832404.1.
YP_588446.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiABD18647; ABD18647; b4517.
BAA35758; BAA35758; BAA35758.
GeneIDi1450249.
KEGGiecj:JW0976.
eco:b4517.
PATRICifig|1411691.4.peg.1280.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiGNSA_ECOLI
AccessioniPrimary (citable) accession number: P0AC92
Secondary accession number(s): P52635, Q2EER1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: July 5, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families