Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Zinc uptake regulation protein

Gene

zur

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Acts as a negative controlling element, employing Zn2+ as a cofactor to bind the operator of the repressed genes (znuACB).

GO - Molecular functioni

GO - Biological processi

  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Zinc

Enzyme and pathway databases

BioCyciEcoCyc:EG11929-MONOMER.
ECOL316407:JW5714-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc uptake regulation protein
Short name:
Zinc uptake regulator
Gene namesi
Name:zur
Synonyms:yjbK
Ordered Locus Names:b4046, JW5714
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11929. zur.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 171171Zinc uptake regulation proteinPRO_0000095592Add
BLAST

Proteomic databases

EPDiP0AC51.
PaxDbiP0AC51.

Interactioni

Protein-protein interaction databases

BioGridi4261723. 7 interactions.
DIPiDIP-12953N.
STRINGi511145.b4046.

Structurei

Secondary structure

1
171
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi5 – 1915Combined sources
Helixi26 – 3712Combined sources
Beta strandi38 – 403Combined sources
Helixi44 – 5411Combined sources
Helixi60 – 7213Combined sources
Beta strandi75 – 795Combined sources
Turni80 – 834Combined sources
Beta strandi84 – 874Combined sources
Beta strandi99 – 1035Combined sources
Turni104 – 1063Combined sources
Beta strandi109 – 1124Combined sources
Helixi115 – 12713Combined sources
Beta strandi131 – 14212Combined sources
Helixi144 – 1518Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4MTDX-ray2.50A/B/C/D1-171[»]
4MTEX-ray2.50A/B/C/D1-171[»]
ProteinModelPortaliP0AC51.
SMRiP0AC51. Positions 2-152.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Fur family.Curated

Phylogenomic databases

eggNOGiENOG4105MYN. Bacteria.
COG0735. LUCA.
HOGENOMiHOG000014146.
InParanoidiP0AC51.
KOiK09823.
OMAiDHSHCVH.
PhylomeDBiP0AC51.

Family and domain databases

CDDicd07153. Fur_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiIPR002481. FUR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01475. FUR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AC51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKTTTQELL AQAEKICAQR NVRLTPQRLE VLRLMSLQDG AISAYDLLDL
60 70 80 90 100
LREAEPQAKP PTVYRALDFL LEQGFVHKVE STNSYVLCHL FDQPTHTSAM
110 120 130 140 150
FICDRCGAVK EECAEGVEDI MHTLAAKMGF ALRHNVIEAH GLCAACVEVE
160 170
ACRHPEQCQH DHSVQVKKKP R
Length:171
Mass (Da):19,254
Last modified:November 8, 2005 - v1
Checksum:i84B712B1BBF00D41
GO

Sequence cautioni

The sequence AAC43140 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00006 Genomic DNA. Translation: AAC43140.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77016.2.
AP009048 Genomic DNA. Translation: BAE78048.1.
PIRiE65212.
RefSeqiNP_418470.4. NC_000913.3.
WP_001295691.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77016; AAC77016; b4046.
BAE78048; BAE78048; BAE78048.
GeneIDi948552.
KEGGiecj:JW5714.
eco:b4046.
PATRICi32123629. VBIEscCol129921_4163.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00006 Genomic DNA. Translation: AAC43140.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77016.2.
AP009048 Genomic DNA. Translation: BAE78048.1.
PIRiE65212.
RefSeqiNP_418470.4. NC_000913.3.
WP_001295691.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4MTDX-ray2.50A/B/C/D1-171[»]
4MTEX-ray2.50A/B/C/D1-171[»]
ProteinModelPortaliP0AC51.
SMRiP0AC51. Positions 2-152.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261723. 7 interactions.
DIPiDIP-12953N.
STRINGi511145.b4046.

Proteomic databases

EPDiP0AC51.
PaxDbiP0AC51.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77016; AAC77016; b4046.
BAE78048; BAE78048; BAE78048.
GeneIDi948552.
KEGGiecj:JW5714.
eco:b4046.
PATRICi32123629. VBIEscCol129921_4163.

Organism-specific databases

EchoBASEiEB1873.
EcoGeneiEG11929. zur.

Phylogenomic databases

eggNOGiENOG4105MYN. Bacteria.
COG0735. LUCA.
HOGENOMiHOG000014146.
InParanoidiP0AC51.
KOiK09823.
OMAiDHSHCVH.
PhylomeDBiP0AC51.

Enzyme and pathway databases

BioCyciEcoCyc:EG11929-MONOMER.
ECOL316407:JW5714-MONOMER.

Miscellaneous databases

PROiP0AC51.

Family and domain databases

CDDicd07153. Fur_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiIPR002481. FUR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01475. FUR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiZUR_ECOLI
AccessioniPrimary (citable) accession number: P0AC51
Secondary accession number(s): P32692, P76784, Q2M6Q8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.