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Protein

Flagellar biosynthetic protein FliP

Gene

fliP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Plays a role in the flagellum-specific transport system.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:EG11975-MONOMER.
ECOL316407:JW1932-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar biosynthetic protein FliP
Gene namesi
Name:fliP
Synonyms:flaR
Ordered Locus Names:b1948, JW1932
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11975. fliP.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei45 – 6521HelicalSequence analysisAdd
BLAST
Transmembranei88 – 10821HelicalSequence analysisAdd
BLAST
Transmembranei185 – 20521HelicalSequence analysisAdd
BLAST
Transmembranei209 – 22921HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121By similarityAdd
BLAST
Chaini22 – 245224Flagellar biosynthetic protein FliPPRO_0000009535Add
BLAST

Proteomic databases

PaxDbiP0AC05.

Interactioni

Protein-protein interaction databases

BioGridi4261044. 426 interactions.
STRINGi511145.b1948.

Structurei

3D structure databases

ProteinModelPortaliP0AC05.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FliP/MopC/SpaP family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CN7. Bacteria.
COG1338. LUCA.
HOGENOMiHOG000253558.
InParanoidiP0AC05.
KOiK02419.
OMAiMPPNQIL.
OrthoDBiEOG6GBMBW.
PhylomeDBiP0AC05.

Family and domain databases

InterProiIPR005837. FliP.
IPR005838. T3SS_IM_P.
[Graphical view]
PANTHERiPTHR30587:SF0. PTHR30587:SF0. 1 hit.
PfamiPF00813. FliP. 1 hit.
[Graphical view]
PRINTSiPR00951. FLGBIOSNFLIP.
PR01302. TYPE3IMPPROT.
TIGRFAMsiTIGR01103. fliP. 1 hit.
PROSITEiPS01060. FLIP_1. 1 hit.
PS01061. FLIP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AC05-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRLLSVAPV LLWLITPLAF AQLPGITSQP LPGGGQSWSL PVQTLVFITS
60 70 80 90 100
LTFIPAILLM MTSFTRIIIV FGLLRNALGT PSAPPNQVLL GLALFLTFFI
110 120 130 140 150
MSPVIDKIYV DAYQPFSEEK ISMQEALEKG AQPLREFMLR QTREADLGLF
160 170 180 190 200
ARLANTGPLQ GPEAVPMRIL LPAYVTSELK TAFQIGFTIF IPFLIIDLVI
210 220 230 240
ASVLMALGMM MVPPATIALP FKLMLFVLVD GWQLLVGSLA QSFYS
Length:245
Mass (Da):26,928
Last modified:November 8, 2005 - v1
Checksum:iC8E84B7B10FD1D26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22182 Genomic DNA. Translation: AAC36859.1.
AP009048 Genomic DNA. Translation: BAA15773.1.
U00096 Genomic DNA. Translation: AAC75015.1.
PIRiB36869.
RefSeqiNP_416458.1. NC_000913.3.
WP_001253441.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75015; AAC75015; b1948.
BAA15773; BAA15773; BAA15773.
GeneIDi946462.
KEGGiecj:JW1932.
eco:b1948.
PATRICi32119225. VBIEscCol129921_2027.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22182 Genomic DNA. Translation: AAC36859.1.
AP009048 Genomic DNA. Translation: BAA15773.1.
U00096 Genomic DNA. Translation: AAC75015.1.
PIRiB36869.
RefSeqiNP_416458.1. NC_000913.3.
WP_001253441.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AC05.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261044. 426 interactions.
STRINGi511145.b1948.

Proteomic databases

PaxDbiP0AC05.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75015; AAC75015; b1948.
BAA15773; BAA15773; BAA15773.
GeneIDi946462.
KEGGiecj:JW1932.
eco:b1948.
PATRICi32119225. VBIEscCol129921_2027.

Organism-specific databases

EchoBASEiEB1918.
EcoGeneiEG11975. fliP.

Phylogenomic databases

eggNOGiENOG4105CN7. Bacteria.
COG1338. LUCA.
HOGENOMiHOG000253558.
InParanoidiP0AC05.
KOiK02419.
OMAiMPPNQIL.
OrthoDBiEOG6GBMBW.
PhylomeDBiP0AC05.

Enzyme and pathway databases

BioCyciEcoCyc:EG11975-MONOMER.
ECOL316407:JW1932-MONOMER.

Miscellaneous databases

PROiP0AC05.

Family and domain databases

InterProiIPR005837. FliP.
IPR005838. T3SS_IM_P.
[Graphical view]
PANTHERiPTHR30587:SF0. PTHR30587:SF0. 1 hit.
PfamiPF00813. FliP. 1 hit.
[Graphical view]
PRINTSiPR00951. FLGBIOSNFLIP.
PR01302. TYPE3IMPPROT.
TIGRFAMsiTIGR01103. fliP. 1 hit.
PROSITEiPS01060. FLIP_1. 1 hit.
PS01061. FLIP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular characterization, nucleotide sequence, and expression of the fliO, fliP, fliQ, and fliR genes of Escherichia coli."
    Malakooti J., Ely B., Matsumura P.
    J. Bacteriol. 176:189-197(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiFLIP_ECOLI
AccessioniPrimary (citable) accession number: P0AC05
Secondary accession number(s): P33133
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: January 20, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.