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Protein

Flavodoxin-2

Gene

fldB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Low-potential electron donor to a number of redox enzymes.Curated

Cofactori

GO - Molecular functioni

  • electron carrier activity Source: InterPro
  • FMN binding Source: EcoCyc

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Flavoprotein, FMN

Enzyme and pathway databases

BioCyciEcoCyc:FLAVODOXIN2-MONOMER.
ECOL316407:JW2863-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flavodoxin-2
Gene namesi
Name:fldB
Ordered Locus Names:b2895, JW2863
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12697. fldB.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001716261 – 173Flavodoxin-2Add BLAST173

Proteomic databases

PaxDbiP0ABY4.
PRIDEiP0ABY4.

Interactioni

Protein-protein interaction databases

BioGridi4262340. 10 interactors.
IntActiP0ABY4. 8 interactors.
STRINGi511145.b2895.

Structurei

Secondary structure

1173
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 7Combined sources5
Beta strandi10 – 12Combined sources3
Helixi13 – 25Combined sources13
Turni27 – 29Combined sources3
Beta strandi30 – 34Combined sources5
Turni35 – 37Combined sources3
Helixi40 – 44Combined sources5
Beta strandi46 – 56Combined sources11
Turni57 – 59Combined sources3
Helixi63 – 68Combined sources6
Helixi71 – 74Combined sources4
Beta strandi81 – 88Combined sources8
Turni90 – 93Combined sources4
Turni95 – 98Combined sources4
Helixi99 – 110Combined sources12
Beta strandi114 – 116Combined sources3
Beta strandi129 – 133Combined sources5
Turni134 – 137Combined sources4
Beta strandi138 – 148Combined sources11
Helixi149 – 151Combined sources3
Helixi153 – 171Combined sources19

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MT9NMR-A1-173[»]
2MTBNMR-A1-173[»]
ProteinModelPortaliP0ABY4.
SMRiP0ABY4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 165Flavodoxin-likePROSITE-ProRule annotationAdd BLAST163

Sequence similaritiesi

Belongs to the flavodoxin family.Curated
Contains 1 flavodoxin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG41071R3. Bacteria.
COG0716. LUCA.
HOGENOMiHOG000030543.
InParanoidiP0ABY4.
KOiK03840.
OMAiILGISTW.
PhylomeDBiP0ABY4.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR001226. Flavodoxin_CS.
IPR010086. Flavodoxin_lc.
IPR029039. Flavoprotein-like_dom.
[Graphical view]
PfamiPF00258. Flavodoxin_1. 1 hit.
[Graphical view]
PIRSFiPIRSF038996. FldA. 1 hit.
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01752. flav_long. 1 hit.
PROSITEiPS00201. FLAVODOXIN. 1 hit.
PS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ABY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMGLFYGSS TCYTEMAAEK IRDIIGPELV TLHNLKDDSP KLMEQYDVLI
60 70 80 90 100
LGIPTWDFGE IQEDWEAVWD QLDDLNLEGK IVALYGLGDQ LGYGEWFLDA
110 120 130 140 150
LGMLHDKLST KGVKFVGYWP TEGYEFTSPK PVIADGQLFV GLALDETNQY
160 170
DLSDERIQSW CEQILNEMAE HYA
Length:173
Mass (Da):19,700
Last modified:October 25, 2005 - v1
Checksum:i89338715D106A68C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti115F → C in CAA88140 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48060 Genomic DNA. Translation: CAA88140.1.
U28375 Genomic DNA. Translation: AAA83076.1.
U00096 Genomic DNA. Translation: AAC75933.1.
AP009048 Genomic DNA. Translation: BAE76960.1.
PIRiG65073.
RefSeqiNP_417371.1. NC_000913.3.
WP_001055874.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75933; AAC75933; b2895.
BAE76960; BAE76960; BAE76960.
GeneIDi947361.
KEGGiecj:JW2863.
eco:b2895.
PATRICi32121202. VBIEscCol129921_2989.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48060 Genomic DNA. Translation: CAA88140.1.
U28375 Genomic DNA. Translation: AAA83076.1.
U00096 Genomic DNA. Translation: AAC75933.1.
AP009048 Genomic DNA. Translation: BAE76960.1.
PIRiG65073.
RefSeqiNP_417371.1. NC_000913.3.
WP_001055874.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MT9NMR-A1-173[»]
2MTBNMR-A1-173[»]
ProteinModelPortaliP0ABY4.
SMRiP0ABY4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262340. 10 interactors.
IntActiP0ABY4. 8 interactors.
STRINGi511145.b2895.

Proteomic databases

PaxDbiP0ABY4.
PRIDEiP0ABY4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75933; AAC75933; b2895.
BAE76960; BAE76960; BAE76960.
GeneIDi947361.
KEGGiecj:JW2863.
eco:b2895.
PATRICi32121202. VBIEscCol129921_2989.

Organism-specific databases

EchoBASEiEB2559.
EcoGeneiEG12697. fldB.

Phylogenomic databases

eggNOGiENOG41071R3. Bacteria.
COG0716. LUCA.
HOGENOMiHOG000030543.
InParanoidiP0ABY4.
KOiK03840.
OMAiILGISTW.
PhylomeDBiP0ABY4.

Enzyme and pathway databases

BioCyciEcoCyc:FLAVODOXIN2-MONOMER.
ECOL316407:JW2863-MONOMER.

Miscellaneous databases

PROiP0ABY4.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR001226. Flavodoxin_CS.
IPR010086. Flavodoxin_lc.
IPR029039. Flavoprotein-like_dom.
[Graphical view]
PfamiPF00258. Flavodoxin_1. 1 hit.
[Graphical view]
PIRSFiPIRSF038996. FldA. 1 hit.
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01752. flav_long. 1 hit.
PROSITEiPS00201. FLAVODOXIN. 1 hit.
PS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFLAW_ECOLI
AccessioniPrimary (citable) accession number: P0ABY4
Secondary accession number(s): P41050, Q2M9U6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 25, 2005
Last modified: November 2, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.