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Protein

Uncharacterized ferredoxin-like protein YfaE

Gene

yfaE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Cofactori

[2Fe-2S] clusterCuratedNote: Binds 1 [2Fe-2S] cluster.Curated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi37 – 371Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation
Metal bindingi42 – 421Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation
Metal bindingi45 – 451Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation
Metal bindingi74 – 741Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation

GO - Molecular functioni

  • 2 iron, 2 sulfur cluster binding Source: EcoCyc
  • electron carrier activity Source: EcoliWiki
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

  • ferredoxin metabolic process Source: EcoliWiki
  • oxidation-reduction process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

2Fe-2S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG12360-MONOMER.
ECOL316407:JW2230-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized ferredoxin-like protein YfaE
Gene namesi
Name:yfaE
Ordered Locus Names:b2236, JW2230
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12360. yfaE.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: EcoliWiki
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8484Uncharacterized ferredoxin-like protein YfaEPRO_0000189416Add
BLAST

Proteomic databases

PaxDbiP0ABW3.

Interactioni

Protein-protein interaction databases

BioGridi4260493. 174 interactions.
STRINGi511145.b2236.

Structurei

3D structure databases

ProteinModelPortaliP0ABW3.
SMRiP0ABW3. Positions 2-84.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 84832Fe-2S ferredoxin-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 2Fe-2S ferredoxin-type domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105XPH. Bacteria.
COG0633. LUCA.
HOGENOMiHOG000217153.
InParanoidiP0ABW3.
KOiK11107.
OMAiYCGSCRC.
OrthoDBiEOG6BPDNN.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR001041. 2Fe-2S_ferredoxin-type.
IPR006058. 2Fe2S_fd_BS.
IPR012675. Beta-grasp_dom.
[Graphical view]
PfamiPF00111. Fer2. 1 hit.
[Graphical view]
SUPFAMiSSF54292. SSF54292. 1 hit.
PROSITEiPS00197. 2FE2S_FER_1. 1 hit.
PS51085. 2FE2S_FER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ABW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARVTLRITG TQLLCQDEHP SLLAALESHN VAVEYQCREG YCGSCRTRLV
60 70 80
AGQVDWIAEP LAFIQPGEIL PCCCRAKGDI EIEM
Length:84
Mass (Da):9,293
Last modified:October 25, 2005 - v1
Checksum:i83DE6DFB1E9E1D7A
GO

Sequence cautioni

The sequence K02672 differs from that shown. Reason: Frameshift at position 28. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02672 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC75296.1.
AP009048 Genomic DNA. Translation: BAA16055.1.
PIRiB64994.
RefSeqiNP_416739.1. NC_000913.3.
WP_000135040.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75296; AAC75296; b2236.
BAA16055; BAA16055; BAA16055.
GeneIDi946729.
KEGGiecj:JW2230.
eco:b2236.
PATRICi32119831. VBIEscCol129921_2325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02672 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC75296.1.
AP009048 Genomic DNA. Translation: BAA16055.1.
PIRiB64994.
RefSeqiNP_416739.1. NC_000913.3.
WP_000135040.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0ABW3.
SMRiP0ABW3. Positions 2-84.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260493. 174 interactions.
STRINGi511145.b2236.

Proteomic databases

PaxDbiP0ABW3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75296; AAC75296; b2236.
BAA16055; BAA16055; BAA16055.
GeneIDi946729.
KEGGiecj:JW2230.
eco:b2236.
PATRICi32119831. VBIEscCol129921_2325.

Organism-specific databases

EchoBASEiEB2263.
EcoGeneiEG12360. yfaE.

Phylogenomic databases

eggNOGiENOG4105XPH. Bacteria.
COG0633. LUCA.
HOGENOMiHOG000217153.
InParanoidiP0ABW3.
KOiK11107.
OMAiYCGSCRC.
OrthoDBiEOG6BPDNN.

Enzyme and pathway databases

BioCyciEcoCyc:EG12360-MONOMER.
ECOL316407:JW2230-MONOMER.

Miscellaneous databases

PROiP0ABW3.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR001041. 2Fe-2S_ferredoxin-type.
IPR006058. 2Fe2S_fd_BS.
IPR012675. Beta-grasp_dom.
[Graphical view]
PfamiPF00111. Fer2. 1 hit.
[Graphical view]
SUPFAMiSSF54292. SSF54292. 1 hit.
PROSITEiPS00197. 2FE2S_FER_1. 1 hit.
PS51085. 2FE2S_FER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Primary structure of the Escherichia coli ribonucleoside diphosphate reductase operon."
    Carlson J., Fuchs J.A., Messing J.
    Proc. Natl. Acad. Sci. U.S.A. 81:4294-4297(1984) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Intrinsic and extrinsic approaches for detecting genes in a bacterial genome."
    Borodovsky M., Rudd K.E., Koonin E.V.
    Nucleic Acids Res. 22:4756-4767(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiYFAE_ECOLI
AccessioniPrimary (citable) accession number: P0ABW3
Secondary accession number(s): P37910, P77220
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 25, 2005
Last modified: April 13, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.