Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein TolR

Gene

tolR

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciECOL386585:GJFA-768-MONOMER.
ECOO157:TOLR-MONOMER.

Protein family/group databases

TCDBi1.A.30.2.2. the h(+)- or na(+)-translocating bacterial flagellar motor/exbbd outer membrane transport energizer (mot/exb) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein TolR
Gene namesi
Name:tolR
Ordered Locus Names:Z0906, ECs0773
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2020CytoplasmicCuratedAdd
BLAST
Transmembranei21 – 4020Helical; Signal-anchor for type II membrane proteinCuratedAdd
BLAST
Topological domaini41 – 142102PeriplasmicCuratedAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 142142Protein TolRPRO_0000129141Add
BLAST

Interactioni

Protein-protein interaction databases

MINTiMINT-100173.
STRINGi155864.Z0906.

Structurei

3D structure databases

ProteinModelPortaliP0ABV8.
SMRiP0ABV8. Positions 37-141.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ExbD/TolR family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105M8F. Bacteria.
COG0848. LUCA.
HOGENOMiHOG000134906.
KOiK03560.
OMAiDNNTMFL.
OrthoDBiEOG6D2KWK.

Family and domain databases

InterProiIPR014168. Biopolymer_transpt_TolR.
IPR003400. ExbD.
[Graphical view]
PfamiPF02472. ExbD. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02801. tolR. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ABV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARARGRGRR DLKSEINIVP LLDVLLVLLL IFMATAPIIT QSVEVDLPDA
60 70 80 90 100
TESQAVSSND NPPVIVEVSG IGQYTVVVEK DRLERLPPEQ VVAEVSSRFK
110 120 130 140
ANPKTVFLIG GAKDVPYDEI IKALNLLHSA GVKSVGLMTQ PI
Length:142
Mass (Da):15,383
Last modified:October 25, 2005 - v1
Checksum:i936FE0033172600B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG55074.1.
BA000007 Genomic DNA. Translation: BAB34196.1.
PIRiE90725.
F85576.
RefSeqiNP_308800.1. NC_002695.1.
WP_000090097.1. NZ_LPWC01000530.1.

Genome annotation databases

EnsemblBacteriaiAAG55074; AAG55074; Z0906.
BAB34196; BAB34196; BAB34196.
GeneIDi917504.
KEGGiece:Z0906.
ecs:ECs0773.
PATRICi18350570. VBIEscCol44059_0796.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG55074.1.
BA000007 Genomic DNA. Translation: BAB34196.1.
PIRiE90725.
F85576.
RefSeqiNP_308800.1. NC_002695.1.
WP_000090097.1. NZ_LPWC01000530.1.

3D structure databases

ProteinModelPortaliP0ABV8.
SMRiP0ABV8. Positions 37-141.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-100173.
STRINGi155864.Z0906.

Protein family/group databases

TCDBi1.A.30.2.2. the h(+)- or na(+)-translocating bacterial flagellar motor/exbbd outer membrane transport energizer (mot/exb) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG55074; AAG55074; Z0906.
BAB34196; BAB34196; BAB34196.
GeneIDi917504.
KEGGiece:Z0906.
ecs:ECs0773.
PATRICi18350570. VBIEscCol44059_0796.

Phylogenomic databases

eggNOGiENOG4105M8F. Bacteria.
COG0848. LUCA.
HOGENOMiHOG000134906.
KOiK03560.
OMAiDNNTMFL.
OrthoDBiEOG6D2KWK.

Enzyme and pathway databases

BioCyciECOL386585:GJFA-768-MONOMER.
ECOO157:TOLR-MONOMER.

Family and domain databases

InterProiIPR014168. Biopolymer_transpt_TolR.
IPR003400. ExbD.
[Graphical view]
PfamiPF02472. ExbD. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02801. tolR. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
  2. "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
    Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.
    , Kuhara S., Shiba T., Hattori M., Shinagawa H.
    DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

Entry informationi

Entry nameiTOLR_ECO57
AccessioniPrimary (citable) accession number: P0ABV8
Secondary accession number(s): P05829
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 25, 2005
Last modified: May 11, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.