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Protein

Protein TolQ

Gene

tolQ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the TonB-independent uptake of group A colicins (colicins A, E1, E2, E3, and K).

GO - Molecular functioni

GO - Biological processi

  • bacteriocin transport Source: EcoCyc
  • protein import Source: EcoliWiki
Complete GO annotation...

Keywords - Biological processi

Bacteriocin transport, Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:EG11010-MONOMER.
ECOL316407:JW0727-MONOMER.

Protein family/group databases

TCDBi1.A.30.2.2. the h(+)- or na(+)-translocating bacterial flagellar motor/exbbd outer membrane transport energizer (mot/exb) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein TolQ
Gene namesi
Name:tolQ
Synonyms:fii
Ordered Locus Names:b0737, JW0727
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11010. tolQ.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 8PeriplasmicCurated8
Transmembranei9 – 36HelicalCuratedAdd BLAST28
Topological domaini37 – 126CytoplasmicCuratedAdd BLAST90
Transmembranei127 – 159HelicalCuratedAdd BLAST33
Topological domaini160 – 161PeriplasmicCurated2
Transmembranei162 – 191HelicalCuratedAdd BLAST30
Topological domaini192 – 230CytoplasmicCuratedAdd BLAST39

GO - Cellular componenti

  • cell division site Source: EcoCyc
  • cell envelope Source: EcoCyc
  • integral component of membrane Source: EcoliWiki
  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001458221 – 230Protein TolQAdd BLAST230

Proteomic databases

PaxDbiP0ABU9.
PRIDEiP0ABU9.

Interactioni

Protein-protein interaction databases

BioGridi4259453. 197 interactors.
DIPiDIP-11008N.
STRINGi511145.b0737.

Structurei

3D structure databases

ProteinModelPortaliP0ABU9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ExbB/TolQ family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E02. Bacteria.
COG0811. LUCA.
HOGENOMiHOG000134795.
InParanoidiP0ABU9.
KOiK03562.
OMAiLESHLPF.
PhylomeDBiP0ABU9.

Family and domain databases

InterProiIPR002898. MotA_ExbB_proton_chnl.
IPR014163. Tol-Pal_TolQ.
[Graphical view]
PfamiPF01618. MotA_ExbB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02796. tolQ. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ABU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDMNILDLF LKASLLVKLI MLILIGFSIA SWAIIIQRTR ILNAAAREAE
60 70 80 90 100
AFEDKFWSGI ELSRLYQESQ GKRDNLTGSE QIFYSGFKEF VRLHRANSHA
110 120 130 140 150
PEAVVEGASR AMRISMNREL ENLETHIPFL GTVGSISPYI GLFGTVWGIM
160 170 180 190 200
HAFIALGAVK QATLQMVAPG IAEALIATAI GLFAAIPAVM AYNRLNQRVN
210 220 230
KLELNYDNFM EEFTAILHRQ AFTVSESNKG
Length:230
Mass (Da):25,598
Last modified:October 25, 2005 - v1
Checksum:iF4356F6C5B0F753C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M16489 Genomic DNA. Translation: AAA83919.1.
U00096 Genomic DNA. Translation: AAC73831.1.
AP009048 Genomic DNA. Translation: BAA35403.1.
PIRiB25980. BVECTQ.
RefSeqiNP_415265.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC73831; AAC73831; b0737.
BAA35403; BAA35403; BAA35403.
GeneIDi948900.
KEGGiecj:JW0727.
eco:b0737.
PATRICi32116673. VBIEscCol129921_0769.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M16489 Genomic DNA. Translation: AAA83919.1.
U00096 Genomic DNA. Translation: AAC73831.1.
AP009048 Genomic DNA. Translation: BAA35403.1.
PIRiB25980. BVECTQ.
RefSeqiNP_415265.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP0ABU9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259453. 197 interactors.
DIPiDIP-11008N.
STRINGi511145.b0737.

Protein family/group databases

TCDBi1.A.30.2.2. the h(+)- or na(+)-translocating bacterial flagellar motor/exbbd outer membrane transport energizer (mot/exb) superfamily.

Proteomic databases

PaxDbiP0ABU9.
PRIDEiP0ABU9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73831; AAC73831; b0737.
BAA35403; BAA35403; BAA35403.
GeneIDi948900.
KEGGiecj:JW0727.
eco:b0737.
PATRICi32116673. VBIEscCol129921_0769.

Organism-specific databases

EchoBASEiEB1003.
EcoGeneiEG11010. tolQ.

Phylogenomic databases

eggNOGiENOG4105E02. Bacteria.
COG0811. LUCA.
HOGENOMiHOG000134795.
InParanoidiP0ABU9.
KOiK03562.
OMAiLESHLPF.
PhylomeDBiP0ABU9.

Enzyme and pathway databases

BioCyciEcoCyc:EG11010-MONOMER.
ECOL316407:JW0727-MONOMER.

Miscellaneous databases

PROiP0ABU9.

Family and domain databases

InterProiIPR002898. MotA_ExbB_proton_chnl.
IPR014163. Tol-Pal_TolQ.
[Graphical view]
PfamiPF01618. MotA_ExbB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02796. tolQ. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTOLQ_ECOLI
AccessioniPrimary (citable) accession number: P0ABU9
Secondary accession number(s): P05828
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 25, 2005
Last modified: November 2, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.