Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein TolQ

Gene

tolQ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the TonB-independent uptake of group A colicins (colicins A, E1, E2, E3, and K).

GO - Molecular functioni

GO - Biological processi

  • bacteriocin transport Source: EcoCyc
  • protein import Source: EcoliWiki
Complete GO annotation...

Keywords - Biological processi

Bacteriocin transport, Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:EG11010-MONOMER.
ECOL316407:JW0727-MONOMER.

Protein family/group databases

TCDBi1.A.30.2.2. the h(+)- or na(+)-translocating bacterial flagellar motor/exbbd outer membrane transport energizer (mot/exb) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein TolQ
Gene namesi
Name:tolQ
Synonyms:fii
Ordered Locus Names:b0737, JW0727
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11010. tolQ.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 88PeriplasmicCurated
Transmembranei9 – 3628HelicalCuratedAdd
BLAST
Topological domaini37 – 12690CytoplasmicCuratedAdd
BLAST
Transmembranei127 – 15933HelicalCuratedAdd
BLAST
Topological domaini160 – 1612PeriplasmicCurated
Transmembranei162 – 19130HelicalCuratedAdd
BLAST
Topological domaini192 – 23039CytoplasmicCuratedAdd
BLAST

GO - Cellular componenti

  • cell division site Source: EcoCyc
  • cell envelope Source: EcoCyc
  • integral component of membrane Source: EcoliWiki
  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 230230Protein TolQPRO_0000145822Add
BLAST

Proteomic databases

PaxDbiP0ABU9.
PRIDEiP0ABU9.

Interactioni

Protein-protein interaction databases

BioGridi4259453. 197 interactions.
DIPiDIP-11008N.
STRINGi511145.b0737.

Structurei

3D structure databases

ProteinModelPortaliP0ABU9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ExbB/TolQ family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E02. Bacteria.
COG0811. LUCA.
HOGENOMiHOG000134795.
InParanoidiP0ABU9.
KOiK03562.
OMAiLESHLPF.
OrthoDBiEOG67MF2K.
PhylomeDBiP0ABU9.

Family and domain databases

InterProiIPR002898. MotA_ExbB_proton_chnl.
IPR014163. Tol-Pal_TolQ.
[Graphical view]
PfamiPF01618. MotA_ExbB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02796. tolQ. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ABU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDMNILDLF LKASLLVKLI MLILIGFSIA SWAIIIQRTR ILNAAAREAE
60 70 80 90 100
AFEDKFWSGI ELSRLYQESQ GKRDNLTGSE QIFYSGFKEF VRLHRANSHA
110 120 130 140 150
PEAVVEGASR AMRISMNREL ENLETHIPFL GTVGSISPYI GLFGTVWGIM
160 170 180 190 200
HAFIALGAVK QATLQMVAPG IAEALIATAI GLFAAIPAVM AYNRLNQRVN
210 220 230
KLELNYDNFM EEFTAILHRQ AFTVSESNKG
Length:230
Mass (Da):25,598
Last modified:October 25, 2005 - v1
Checksum:iF4356F6C5B0F753C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M16489 Genomic DNA. Translation: AAA83919.1.
U00096 Genomic DNA. Translation: AAC73831.1.
AP009048 Genomic DNA. Translation: BAA35403.1.
PIRiB25980. BVECTQ.
RefSeqiNP_415265.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC73831; AAC73831; b0737.
BAA35403; BAA35403; BAA35403.
GeneIDi948900.
KEGGiecj:JW0727.
eco:b0737.
PATRICi32116673. VBIEscCol129921_0769.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M16489 Genomic DNA. Translation: AAA83919.1.
U00096 Genomic DNA. Translation: AAC73831.1.
AP009048 Genomic DNA. Translation: BAA35403.1.
PIRiB25980. BVECTQ.
RefSeqiNP_415265.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP0ABU9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259453. 197 interactions.
DIPiDIP-11008N.
STRINGi511145.b0737.

Protein family/group databases

TCDBi1.A.30.2.2. the h(+)- or na(+)-translocating bacterial flagellar motor/exbbd outer membrane transport energizer (mot/exb) superfamily.

Proteomic databases

PaxDbiP0ABU9.
PRIDEiP0ABU9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73831; AAC73831; b0737.
BAA35403; BAA35403; BAA35403.
GeneIDi948900.
KEGGiecj:JW0727.
eco:b0737.
PATRICi32116673. VBIEscCol129921_0769.

Organism-specific databases

EchoBASEiEB1003.
EcoGeneiEG11010. tolQ.

Phylogenomic databases

eggNOGiENOG4105E02. Bacteria.
COG0811. LUCA.
HOGENOMiHOG000134795.
InParanoidiP0ABU9.
KOiK03562.
OMAiLESHLPF.
OrthoDBiEOG67MF2K.
PhylomeDBiP0ABU9.

Enzyme and pathway databases

BioCyciEcoCyc:EG11010-MONOMER.
ECOL316407:JW0727-MONOMER.

Miscellaneous databases

PROiP0ABU9.

Family and domain databases

InterProiIPR002898. MotA_ExbB_proton_chnl.
IPR014163. Tol-Pal_TolQ.
[Graphical view]
PfamiPF01618. MotA_ExbB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02796. tolQ. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of a gene cluster involved in entry of E colicins and single-stranded DNA of infecting filamentous bacteriophages into Escherichia coli."
    Sun T.-P., Webster R.E.
    J. Bacteriol. 169:2667-2674(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Membrane topology of the Escherichia coli TolR protein required for cell envelope integrity."
    Muller M.M., Vianney A., Lazzaroni J.-C., Webster R.E., Portalier R.
    J. Bacteriol. 175:6059-6061(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY.
  6. "Membrane topologies of the TolQ and TolR proteins of Escherichia coli: inactivation of TolQ by a missense mutation in the proposed first transmembrane segment."
    Kampfenkel K., Braun V.
    J. Bacteriol. 175:4485-4491(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY.
  7. "Membrane topology and mutational analysis of the TolQ protein of Escherichia coli required for the uptake of macromolecules and cell envelope integrity."
    Vianney A., Lewin T.M., Beyer W.F. Jr., Lazzaroni J.C., Portalier R., Webster R.E.
    J. Bacteriol. 176:822-829(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY.
  8. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiTOLQ_ECOLI
AccessioniPrimary (citable) accession number: P0ABU9
Secondary accession number(s): P05828
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 25, 2005
Last modified: March 16, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.