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Protein

DNA damage-inducible protein I

Gene

dinI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in SOS regulation. Inhibits RecA by preventing RecA to bind ssDNA. Can displace ssDNA from RecA.

GO - Molecular functioni

  • enzyme binding Source: EcoCyc

GO - Biological processi

  • DNA repair Source: UniProtKB-KW
  • SOS response Source: EcoCyc

Keywordsi

Biological processDNA damage, DNA repair, SOS response

Enzyme and pathway databases

BioCyciEcoCyc:G6558-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA damage-inducible protein I
Gene namesi
Name:dinI
Ordered Locus Names:b1061, JW1048
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12670 dinI

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002016351 – 81DNA damage-inducible protein IAdd BLAST81

Proteomic databases

PaxDbiP0ABR1
PRIDEiP0ABR1

Interactioni

GO - Molecular functioni

  • enzyme binding Source: EcoCyc

Protein-protein interaction databases

BioGridi4261873, 136 interactors
DIPiDIP-9445N
STRINGi316385.ECDH10B_1132

Structurei

Secondary structure

181
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 8Combined sources7
Helixi17 – 32Combined sources16
Beta strandi34 – 36Combined sources3
Beta strandi39 – 47Combined sources9
Beta strandi49 – 54Combined sources6
Helixi57 – 72Combined sources16
Helixi74 – 77Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GHHNMR-A1-81[»]
ProteinModelPortaliP0ABR1
SMRiP0ABR1
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0ABR1

Family & Domainsi

Sequence similaritiesi

Belongs to the DinI family.Curated

Phylogenomic databases

eggNOGiENOG4105MEA Bacteria
ENOG4111VX8 LUCA
HOGENOMiHOG000276614
KOiK12149
OMAiTPWCHSS

Family and domain databases

Gene3Di3.30.910.10, 1 hit
InterProiView protein in InterPro
IPR036687 DinI-like_sf
IPR010391 DNA_damage-inducible_DinI-like
PANTHERiPTHR36572 PTHR36572, 1 hit
PfamiView protein in Pfam
PF06183 DinI, 1 hit
SUPFAMiSSF54857 SSF54857, 1 hit

Sequencei

Sequence statusi: Complete.

P0ABR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIEVTIAKT SPLPAGAIDA LAGELSRRIQ YAFPDNEGHV SVRYAAANNL
60 70 80
SVIGATKEDK QRISEILQET WESADDWFVS E
Length:81
Mass (Da):8,949
Last modified:November 8, 2005 - v1
Checksum:i67B706F3741C4E65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D31709 Genomic DNA Translation: BAA06515.1
U00096 Genomic DNA Translation: AAC74145.1
AP009048 Genomic DNA Translation: BAA35858.2
PIRiB64849
RefSeqiNP_415579.1, NC_000913.3
WP_001217754.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74145; AAC74145; b1061
BAA35858; BAA35858; BAA35858
GeneIDi945022
KEGGiecj:JW1048
eco:b1061
PATRICifig|1411691.4.peg.1207

Similar proteinsi

Entry informationi

Entry nameiDINI_ECOLI
AccessioniPrimary (citable) accession number: P0ABR1
Secondary accession number(s): Q47143, Q9R2Y7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: March 28, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health