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Protein

Diacylglycerol kinase

Gene

dgkA

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Recycling of diacylglycerol produced during the turnover of membrane phospholipid.By similarity

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinase (EC:2.7.1.107)
Short name:
DAGK
Alternative name(s):
Diglyceride kinase
Short name:
DGK
Gene namesi
Name:dgkA
Ordered Locus Names:Z5641, ECs5025
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini2 – 33CytoplasmicBy similarityAdd BLAST32
Transmembranei34 – 49HelicalBy similarityAdd BLAST16
Topological domaini50 – 52PeriplasmicBy similarity3
Transmembranei53 – 69HelicalBy similarityAdd BLAST17
Topological domaini70 – 95CytoplasmicBy similarityAdd BLAST26
Transmembranei96 – 119HelicalBy similarityAdd BLAST24
Topological domaini120 – 122PeriplasmicBy similarity3

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001952612 – 122Diacylglycerol kinaseAdd BLAST121

Interactioni

Protein-protein interaction databases

STRINGi155864.Z5641

Structurei

3D structure databases

ProteinModelPortaliP0ABN3
SMRiP0ABN3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41080IJ Bacteria
COG0818 LUCA
HOGENOMiHOG000014819
KOiK00901
OMAiITNEWHE

Family and domain databases

CDDicd14264 DAGK_IM, 1 hit
Gene3Di1.10.3830.10, 1 hit
InterProiView protein in InterPro
IPR000829 DAGK
IPR033718 DAGK_prok
IPR036945 DAGK_sf
PfamiView protein in Pfam
PF01219 DAGK_prokar, 1 hit
PROSITEiView protein in PROSITE
PS01069 DAGK_PROKAR, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0ABN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANNTTGFTR IIKAAGYSWK GLRAAWINEA AFRQEGVAVL LAVVIACWLD
60 70 80 90 100
VDAITRVLLI SSVMLVMIVE ILNSAIEAVV DRIGSEYHEL SGRAKDMGSA
110 120
AVLIAIIVAV ITWCILLWSH FG
Length:122
Mass (Da):13,245
Last modified:January 23, 2007 - v2
Checksum:iD5B4F86925FA6A17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG59241.1
BA000007 Genomic DNA Translation: BAB38448.1
PIRiA91257
E86097
RefSeqiNP_313052.1, NC_002695.1
WP_000002907.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG59241; AAG59241; Z5641
BAB38448; BAB38448; BAB38448
GeneIDi914310
KEGGiece:Z5641
ecs:ECs5025
PATRICifig|386585.9.peg.5248

Similar proteinsi

Entry informationi

Entry nameiKDGL_ECO57
AccessioniPrimary (citable) accession number: P0ABN3
Secondary accession number(s): P00556
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 76 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health