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P0ABN3 (KDGL_ECO57) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Diacylglycerol kinase

Short name=DAGK
EC=2.7.1.107
Alternative name(s):
Diglyceride kinase
Short name=DGK
Gene names
Name:dgkA
Ordered Locus Names:Z5641, ECs5025
OrganismEscherichia coli O157:H7 [Complete proteome] [HAMAP]
Taxonomic identifier83334 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length122 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Recycling of diacylglycerol produced during the turnover of membrane phospholipid By similarity.

Catalytic activity

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the bacterial diacylglycerol kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 122121Diacylglycerol kinase
PRO_0000195261

Regions

Topological domain2 – 3332Cytoplasmic By similarity
Transmembrane34 – 4916Helical; By similarity
Topological domain50 – 523Periplasmic By similarity
Transmembrane53 – 6917Helical; By similarity
Topological domain70 – 9526Cytoplasmic By similarity
Transmembrane96 – 11924Helical; By similarity
Topological domain120 – 1223Periplasmic By similarity

Sequences

Sequence LengthMass (Da)Tools
P0ABN3 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: D5B4F86925FA6A17

FASTA12213,245
        10         20         30         40         50         60 
MANNTTGFTR IIKAAGYSWK GLRAAWINEA AFRQEGVAVL LAVVIACWLD VDAITRVLLI 

        70         80         90        100        110        120 
SSVMLVMIVE ILNSAIEAVV DRIGSEYHEL SGRAKDMGSA AVLIAIIVAV ITWCILLWSH 


FG 

« Hide

References

[1]"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7."
Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W. expand/collapse author list , Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R.
Nature 409:529-533(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
[2]"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T. expand/collapse author list , Kuhara S., Shiba T., Hattori M., Shinagawa H.
DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005174 Genomic DNA. Translation: AAG59241.1.
BA000007 Genomic DNA. Translation: BAB38448.1.
PIRA91257.
E86097.
RefSeqNP_290676.1. NC_002655.2.
NP_313052.1. NC_002695.1.

3D structure databases

ProteinModelPortalP0ABN3.
SMRP0ABN3. Positions 7-121.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING155864.Z5641.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG59241; AAG59241; Z5641.
BAB38448; BAB38448; BAB38448.
GeneID914310.
960081.
KEGGece:Z5641.
ecs:ECs5025.
PATRIC18359645. VBIEscCol44059_4959.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0818.
HOGENOMHOG000014819.
KOK00901.
OMAAFRHELF.
OrthoDBEOG60W7XM.
ProtClustDBCLSK879806.

Enzyme and pathway databases

BioCycECOL386585:GJFA-5028-MONOMER.
ECOO157:DGKA-MONOMER.

Family and domain databases

InterProIPR000829. Diacylglycerol_kinase_prok.
[Graphical view]
PfamPF01219. DAGK_prokar. 1 hit.
[Graphical view]
PROSITEPS01069. DAGK_PROKAR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKDGL_ECO57
AccessionPrimary (citable) accession number: P0ABN3
Secondary accession number(s): P00556
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 52 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families