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P0ABN2

- KDGL_ECOL6

UniProt

P0ABN2 - KDGL_ECOL6

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Protein

Diacylglycerol kinase

Gene

dgkA

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Recycling of diacylglycerol produced during the turnover of membrane phospholipid.By similarity

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. diacylglycerol kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. phospholipid biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciECOL199310:C5013-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinase (EC:2.7.1.107)
Short name:
DAGK
Alternative name(s):
Diglyceride kinase
Short name:
DGK
Gene namesi
Name:dgkA
Ordered Locus Names:c5013
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001410: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 122121Diacylglycerol kinasePRO_0000195262Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi199310.c5013.

Structurei

3D structure databases

ProteinModelPortaliP0ABN2.
SMRiP0ABN2. Positions 7-121.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini2 – 3332CytoplasmicBy similarityAdd
BLAST
Topological domaini50 – 523PeriplasmicBy similarity
Topological domaini70 – 9526CytoplasmicBy similarityAdd
BLAST
Topological domaini120 – 1223PeriplasmicBy similarity

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei34 – 4916HelicalBy similarityAdd
BLAST
Transmembranei53 – 6917HelicalBy similarityAdd
BLAST
Transmembranei96 – 11924HelicalBy similarityAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000014819.
KOiK00901.
OMAiFKNTSYA.
OrthoDBiEOG60W7XM.

Family and domain databases

InterProiIPR000829. Diacylglycerol_kinase_prok.
[Graphical view]
PfamiPF01219. DAGK_prokar. 1 hit.
[Graphical view]
PROSITEiPS01069. DAGK_PROKAR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0ABN2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MANNTTGFTR IIKAAGYSWK GLRAAWINEA AFRQEGVAVL LAVVIACWLD
60 70 80 90 100
VDAITRVLLI SSVMLVMIVE ILNSAIEAVV DRIGSEYHEL SGRAKDMGSA
110 120
AVLIAIIVAV ITWCILLWSH FG
Length:122
Mass (Da):13,245
Last modified:January 23, 2007 - v2
Checksum:iD5B4F86925FA6A17
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014075 Genomic DNA. Translation: AAN83439.1.
RefSeqiNP_756865.1. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN83439; AAN83439; c5013.
GeneIDi1039398.
KEGGiecc:c5013.
PATRICi18287718. VBIEscCol75197_4705.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014075 Genomic DNA. Translation: AAN83439.1 .
RefSeqi NP_756865.1. NC_004431.1.

3D structure databases

ProteinModelPortali P0ABN2.
SMRi P0ABN2. Positions 7-121.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 199310.c5013.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN83439 ; AAN83439 ; c5013 .
GeneIDi 1039398.
KEGGi ecc:c5013.
PATRICi 18287718. VBIEscCol75197_4705.

Phylogenomic databases

HOGENOMi HOG000014819.
KOi K00901.
OMAi FKNTSYA.
OrthoDBi EOG60W7XM.

Enzyme and pathway databases

BioCyci ECOL199310:C5013-MONOMER.

Family and domain databases

InterProi IPR000829. Diacylglycerol_kinase_prok.
[Graphical view ]
Pfami PF01219. DAGK_prokar. 1 hit.
[Graphical view ]
PROSITEi PS01069. DAGK_PROKAR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFT073 / ATCC 700928 / UPEC.

Entry informationi

Entry nameiKDGL_ECOL6
AccessioniPrimary (citable) accession number: P0ABN2
Secondary accession number(s): P00556
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3