SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P0ABL8

- CCMB_ECOLI

UniProt

P0ABL8 - CCMB_ECOLI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Heme exporter protein B
Gene
ccmB, yejV, b2200, JW2188
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

GO - Molecular functioni

  1. heme-transporting ATPase activity Source: EcoCyc

GO - Biological processi

  1. cytochrome complex assembly Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cytochrome c-type biogenesis, Transport

Enzyme and pathway databases

BioCyciEcoCyc:CCMB-MONOMER.
ECOL316407:JW2188-MONOMER.
MetaCyc:CCMB-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Heme exporter protein B
Alternative name(s):
Cytochrome c-type biogenesis protein CcmB
Gene namesi
Name:ccmB
Synonyms:yejV
Ordered Locus Names:b2200, JW2188
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG12058. ccmB.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2020Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei21 – 4121Helical; Reviewed prediction
Add
BLAST
Topological domaini42 – 443Periplasmic Reviewed prediction
Transmembranei45 – 6521Helical; Reviewed prediction
Add
BLAST
Topological domaini66 – 10035Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei101 – 12121Helical; Reviewed prediction
Add
BLAST
Topological domaini122 – 1276Periplasmic Reviewed prediction
Transmembranei128 – 14821Helical; Reviewed prediction
Add
BLAST
Topological domaini149 – 15810Cytoplasmic Reviewed prediction
Transmembranei159 – 17921Helical; Reviewed prediction
Add
BLAST
Topological domaini180 – 19213Periplasmic Reviewed prediction
Add
BLAST
Transmembranei193 – 21321Helical; Reviewed prediction
Add
BLAST
Topological domaini214 – 2207Cytoplasmic Reviewed prediction

GO - Cellular componenti

  1. ATP-binding cassette (ABC) transporter complex Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 220220Heme exporter protein B
PRO_0000201539Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP0ABL8.

Interactioni

Protein-protein interaction databases

DIPiDIP-48046N.
IntActiP0ABL8. 9 interactions.
MINTiMINT-1250139.
STRINGi511145.b2200.

Structurei

3D structure databases

ProteinModelPortaliP0ABL8.

Family & Domainsi

Sequence similaritiesi

Belongs to the CcmB/CycW/HelB family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2386.
HOGENOMiHOG000274626.
KOiK02194.
OMAiTGHLLWL.
OrthoDBiEOG64FKHN.
PhylomeDBiP0ABL8.

Family and domain databases

InterProiIPR003544. Cyt_c_biogenesis_CcmB.
IPR026031. Cyt_c_CcmB_bac.
[Graphical view]
PfamiPF03379. CcmB. 1 hit.
[Graphical view]
PIRSFiPIRSF002764. CcmB. 1 hit.
PRINTSiPR01414. CCMBBIOGNSIS.
TIGRFAMsiTIGR01190. ccmB. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ABL8-1 [UniParc]FASTAAdd to Basket

« Hide

MMFWRIFRLE LRVAFRHSAE IANPLWFFLI VITLFPLSIG PEPQLLARIA    50
PGIIWVAALL SSLLALERLF RDDLQDGSLE QLMLLPLPLP AVVLAKVMAH 100
WMVTGLPLLI LSPLVAMLLG MDVYGWQVMA LTLLLGTPTL GFLGAPGVAL 150
TVGLKRGGVL LSILVLPLTI PLLIFATAAM DAASMHLPVD GYLAILGALL 200
AGTATLSPFA TAAALRISIQ 220
Length:220
Mass (Da):23,619
Last modified:November 8, 2005 - v1
Checksum:i8DC1EEB8168401A3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00008 Genomic DNA. Translation: AAA16392.1.
U00096 Genomic DNA. Translation: AAC75260.1.
AP009048 Genomic DNA. Translation: BAE76663.1.
PIRiF64989.
RefSeqiNP_416704.1. NC_000913.3.
YP_490438.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC75260; AAC75260; b2200.
BAE76663; BAE76663; BAE76663.
GeneIDi12931491.
946692.
KEGGiecj:Y75_p2161.
eco:b2200.
PATRICi32119759. VBIEscCol129921_2289.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00008 Genomic DNA. Translation: AAA16392.1 .
U00096 Genomic DNA. Translation: AAC75260.1 .
AP009048 Genomic DNA. Translation: BAE76663.1 .
PIRi F64989.
RefSeqi NP_416704.1. NC_000913.3.
YP_490438.1. NC_007779.1.

3D structure databases

ProteinModelPortali P0ABL8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-48046N.
IntActi P0ABL8. 9 interactions.
MINTi MINT-1250139.
STRINGi 511145.b2200.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC75260 ; AAC75260 ; b2200 .
BAE76663 ; BAE76663 ; BAE76663 .
GeneIDi 12931491.
946692.
KEGGi ecj:Y75_p2161.
eco:b2200.
PATRICi 32119759. VBIEscCol129921_2289.

Organism-specific databases

EchoBASEi EB1988.
EcoGenei EG12058. ccmB.

Phylogenomic databases

eggNOGi COG2386.
HOGENOMi HOG000274626.
KOi K02194.
OMAi TGHLLWL.
OrthoDBi EOG64FKHN.
PhylomeDBi P0ABL8.

Enzyme and pathway databases

BioCyci EcoCyc:CCMB-MONOMER.
ECOL316407:JW2188-MONOMER.
MetaCyc:CCMB-MONOMER.

Miscellaneous databases

PROi P0ABL8.

Gene expression databases

Genevestigatori P0ABL8.

Family and domain databases

InterProi IPR003544. Cyt_c_biogenesis_CcmB.
IPR026031. Cyt_c_CcmB_bac.
[Graphical view ]
Pfami PF03379. CcmB. 1 hit.
[Graphical view ]
PIRSFi PIRSF002764. CcmB. 1 hit.
PRINTSi PR01414. CCMBBIOGNSIS.
TIGRFAMsi TIGR01190. ccmB. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Automated multiplex sequencing of the E.coli genome."
    Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K., Church G.M.
    Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / BHB2600.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Escherichia coli genes required for cytochrome c maturation."
    Thoeny-Meyer L., Fischer F., Kunzler P., Ritz D., Hennecke H.
    J. Bacteriol. 177:4321-4326(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION, GENE NAME.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiCCMB_ECOLI
AccessioniPrimary (citable) accession number: P0ABL8
Secondary accession number(s): P33930, Q2MAP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: July 9, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi