Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P0ABL6

- NAPC_ECOL6

UniProt

P0ABL6 - NAPC_ECOL6

Protein

Cytochrome c-type protein NapC

Gene

napC

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Mediates electron flow from quinones to the NapAB complex.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei57 – 571Heme 1 (covalent)By similarity
    Binding sitei60 – 601Heme 1 (covalent)By similarity
    Metal bindingi61 – 611Iron (heme 1 axial ligand)By similarity
    Binding sitei87 – 871Heme 2 (covalent)By similarity
    Binding sitei90 – 901Heme 2 (covalent)By similarity
    Metal bindingi91 – 911Iron (heme 2 axial ligand)By similarity
    Binding sitei147 – 1471Heme 3 (covalent)By similarity
    Binding sitei150 – 1501Heme 3 (covalent)By similarity
    Metal bindingi151 – 1511Iron (heme 3 axial ligand)By similarity
    Binding sitei179 – 1791Heme 4 (covalent)By similarity
    Binding sitei182 – 1821Heme 4 (covalent)By similarity
    Metal bindingi183 – 1831Iron (heme 4 axial ligand)By similarity

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. denitrification pathway Source: InterPro
    2. oxidation-reduction process Source: UniProtKB-KW

    Keywords - Biological processi

    Electron transport, Transport

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciECOL199310:C2739-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c-type protein NapC
    Gene namesi
    Name:napC
    Ordered Locus Names:c2739
    OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
    Taxonomic identifieri199310 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000001410: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 200200Cytochrome c-type protein NapCPRO_0000108434Add
    BLAST

    Post-translational modificationi

    Binds 4 heme groups per subunit.Curated

    Interactioni

    Protein-protein interaction databases

    STRINGi199310.c2739.

    Structurei

    3D structure databases

    ProteinModelPortaliP0ABL6.
    SMRiP0ABL6. Positions 29-188.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2323CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini45 – 200156PeriplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei24 – 4421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000275532.
    KOiK02569.
    OMAiMDFTAQK.
    OrthoDBiEOG6RNQDS.

    Family and domain databases

    InterProiIPR011031. Multihaem_cyt.
    IPR024717. NapC/NirT/NrfH.
    IPR005126. NapC/NirT_cyt_c_N.
    IPR011885. NO3Rdtase_cyt_c_NapC/NirT.
    [Graphical view]
    PfamiPF03264. Cytochrom_NNT. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000013. 4_hem_cytochrm_NapC. 1 hit.
    TIGRFAMsiTIGR02161. napC_nirT. 1 hit.
    PROSITEiPS51008. MULTIHEME_CYTC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P0ABL6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGNSDRKPGL IKRLWKWWRT PSRLALGTLL LIGFVGGIVF WGGFNTGMEK    50
    ANTEEFCISC HEMRNTVYQE YMDSVHYNNR SGVRATCPDC HVPHEFVPKM 100
    IRKLKASKEL YGKIFGVIDT PQKFEAHRLT MAQNEWRRMK DNNSQECRNC 150
    HNFEYMDTTA QKSVAAKMHD QAVKDGQTCI DCHKGIAHKL PDMREVEPGF 200
    Length:200
    Mass (Da):23,101
    Last modified:November 8, 2005 - v1
    Checksum:iE86A62ABE46AAAA3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014075 Genomic DNA. Translation: AAN81193.1.
    RefSeqiNP_754625.1. NC_004431.1.

    Genome annotation databases

    EnsemblBacteriaiAAN81193; AAN81193; c2739.
    GeneIDi1038151.
    KEGGiecc:c2739.
    PATRICi18283348. VBIEscCol75197_2581.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014075 Genomic DNA. Translation: AAN81193.1 .
    RefSeqi NP_754625.1. NC_004431.1.

    3D structure databases

    ProteinModelPortali P0ABL6.
    SMRi P0ABL6. Positions 29-188.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 199310.c2739.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN81193 ; AAN81193 ; c2739 .
    GeneIDi 1038151.
    KEGGi ecc:c2739.
    PATRICi 18283348. VBIEscCol75197_2581.

    Phylogenomic databases

    HOGENOMi HOG000275532.
    KOi K02569.
    OMAi MDFTAQK.
    OrthoDBi EOG6RNQDS.

    Enzyme and pathway databases

    BioCyci ECOL199310:C2739-MONOMER.

    Family and domain databases

    InterProi IPR011031. Multihaem_cyt.
    IPR024717. NapC/NirT/NrfH.
    IPR005126. NapC/NirT_cyt_c_N.
    IPR011885. NO3Rdtase_cyt_c_NapC/NirT.
    [Graphical view ]
    Pfami PF03264. Cytochrom_NNT. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000013. 4_hem_cytochrm_NapC. 1 hit.
    TIGRFAMsi TIGR02161. napC_nirT. 1 hit.
    PROSITEi PS51008. MULTIHEME_CYTC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CFT073 / ATCC 700928 / UPEC.

    Entry informationi

    Entry nameiNAPC_ECOL6
    AccessioniPrimary (citable) accession number: P0ABL6
    Secondary accession number(s): P33932
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2005
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3