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P0ABL6

- NAPC_ECOL6

UniProt

P0ABL6 - NAPC_ECOL6

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Protein
Cytochrome c-type protein NapC
Gene
napC, c2739
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Mediates electron flow from quinones to the NapAB complex By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei57 – 571Heme 1 (covalent) By similarity
Binding sitei60 – 601Heme 1 (covalent) By similarity
Metal bindingi61 – 611Iron (heme 1 axial ligand) By similarity
Binding sitei87 – 871Heme 2 (covalent) By similarity
Binding sitei90 – 901Heme 2 (covalent) By similarity
Metal bindingi91 – 911Iron (heme 2 axial ligand) By similarity
Binding sitei147 – 1471Heme 3 (covalent) By similarity
Binding sitei150 – 1501Heme 3 (covalent) By similarity
Metal bindingi151 – 1511Iron (heme 3 axial ligand) By similarity
Binding sitei179 – 1791Heme 4 (covalent) By similarity
Binding sitei182 – 1821Heme 4 (covalent) By similarity
Metal bindingi183 – 1831Iron (heme 4 axial ligand) By similarity

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. denitrification pathway Source: InterPro
  2. oxidation-reduction process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciECOL199310:C2739-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c-type protein NapC
Gene namesi
Name:napC
Ordered Locus Names:c2739
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001410: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2323Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei24 – 4421Helical; Reviewed prediction
Add
BLAST
Topological domaini45 – 200156Periplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 200200Cytochrome c-type protein NapC
PRO_0000108434Add
BLAST

Post-translational modificationi

Binds 4 heme groups per subunit Reviewed prediction.

Interactioni

Protein-protein interaction databases

STRINGi199310.c2739.

Structurei

3D structure databases

ProteinModelPortaliP0ABL6.
SMRiP0ABL6. Positions 29-188.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000275532.
KOiK02569.
OMAiMDFTAQK.
OrthoDBiEOG6RNQDS.

Family and domain databases

InterProiIPR011031. Multihaem_cyt.
IPR024717. NapC/NirT/NrfH.
IPR005126. NapC/NirT_cyt_c_N.
IPR011885. NO3Rdtase_cyt_c_NapC/NirT.
[Graphical view]
PfamiPF03264. Cytochrom_NNT. 1 hit.
[Graphical view]
PIRSFiPIRSF000013. 4_hem_cytochrm_NapC. 1 hit.
TIGRFAMsiTIGR02161. napC_nirT. 1 hit.
PROSITEiPS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0ABL6-1 [UniParc]FASTAAdd to Basket

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MGNSDRKPGL IKRLWKWWRT PSRLALGTLL LIGFVGGIVF WGGFNTGMEK    50
ANTEEFCISC HEMRNTVYQE YMDSVHYNNR SGVRATCPDC HVPHEFVPKM 100
IRKLKASKEL YGKIFGVIDT PQKFEAHRLT MAQNEWRRMK DNNSQECRNC 150
HNFEYMDTTA QKSVAAKMHD QAVKDGQTCI DCHKGIAHKL PDMREVEPGF 200
Length:200
Mass (Da):23,101
Last modified:November 8, 2005 - v1
Checksum:iE86A62ABE46AAAA3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014075 Genomic DNA. Translation: AAN81193.1.
RefSeqiNP_754625.1. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN81193; AAN81193; c2739.
GeneIDi1038151.
KEGGiecc:c2739.
PATRICi18283348. VBIEscCol75197_2581.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014075 Genomic DNA. Translation: AAN81193.1 .
RefSeqi NP_754625.1. NC_004431.1.

3D structure databases

ProteinModelPortali P0ABL6.
SMRi P0ABL6. Positions 29-188.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 199310.c2739.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN81193 ; AAN81193 ; c2739 .
GeneIDi 1038151.
KEGGi ecc:c2739.
PATRICi 18283348. VBIEscCol75197_2581.

Phylogenomic databases

HOGENOMi HOG000275532.
KOi K02569.
OMAi MDFTAQK.
OrthoDBi EOG6RNQDS.

Enzyme and pathway databases

BioCyci ECOL199310:C2739-MONOMER.

Family and domain databases

InterProi IPR011031. Multihaem_cyt.
IPR024717. NapC/NirT/NrfH.
IPR005126. NapC/NirT_cyt_c_N.
IPR011885. NO3Rdtase_cyt_c_NapC/NirT.
[Graphical view ]
Pfami PF03264. Cytochrom_NNT. 1 hit.
[Graphical view ]
PIRSFi PIRSF000013. 4_hem_cytochrm_NapC. 1 hit.
TIGRFAMsi TIGR02161. napC_nirT. 1 hit.
PROSITEi PS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFT073 / ATCC 700928 / UPEC.

Entry informationi

Entry nameiNAPC_ECOL6
AccessioniPrimary (citable) accession number: P0ABL6
Secondary accession number(s): P33932
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: May 14, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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