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P0ABL6 (NAPC_ECOL6) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome c-type protein NapC
Gene names
Name:napC
Ordered Locus Names:c2739
OrganismEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) [Complete proteome] [HAMAP]
Taxonomic identifier199310 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Mediates electron flow from quinones to the NapAB complex By similarity.

Subcellular location

Cell inner membrane; Single-pass membrane protein.

Post-translational modification

Binds 4 heme groups per subunit Potential.

Ontologies

Keywords
   Biological processElectron transport
Transport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   LigandHeme
Iron
Metal-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processdenitrification pathway

Inferred from electronic annotation. Source: InterPro

electron transport chain

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionheme binding

Inferred from electronic annotation. Source: InterPro

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 200200Cytochrome c-type protein NapC
PRO_0000108434

Regions

Topological domain1 – 2323Cytoplasmic Potential
Transmembrane24 – 4421Helical; Potential
Topological domain45 – 200156Periplasmic Potential

Sites

Metal binding611Iron (heme 1 axial ligand) By similarity
Metal binding911Iron (heme 2 axial ligand) By similarity
Metal binding1511Iron (heme 3 axial ligand) By similarity
Metal binding1831Iron (heme 4 axial ligand) By similarity
Binding site571Heme 1 (covalent) By similarity
Binding site601Heme 1 (covalent) By similarity
Binding site871Heme 2 (covalent) By similarity
Binding site901Heme 2 (covalent) By similarity
Binding site1471Heme 3 (covalent) By similarity
Binding site1501Heme 3 (covalent) By similarity
Binding site1791Heme 4 (covalent) By similarity
Binding site1821Heme 4 (covalent) By similarity

Sequences

Sequence LengthMass (Da)Tools
P0ABL6 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: E86A62ABE46AAAA3

FASTA20023,101
        10         20         30         40         50         60 
MGNSDRKPGL IKRLWKWWRT PSRLALGTLL LIGFVGGIVF WGGFNTGMEK ANTEEFCISC 

        70         80         90        100        110        120 
HEMRNTVYQE YMDSVHYNNR SGVRATCPDC HVPHEFVPKM IRKLKASKEL YGKIFGVIDT 

       130        140        150        160        170        180 
PQKFEAHRLT MAQNEWRRMK DNNSQECRNC HNFEYMDTTA QKSVAAKMHD QAVKDGQTCI 

       190        200 
DCHKGIAHKL PDMREVEPGF

« Hide

References

[1]"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli."
Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R.
Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CFT073 / ATCC 700928 / UPEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014075 Genomic DNA. Translation: AAN81193.1.
RefSeqNP_754625.1. NC_004431.1.

3D structure databases

ProteinModelPortalP0ABL6.
SMRP0ABL6. Positions 29-188.
ModBaseSearch...

Protein-protein interaction databases

STRING199310.c2739.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN81193; AAN81193; c2739.
GeneID1038151.
KEGGecc:c2739.
PATRIC18283348. VBIEscCol75197_2581.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000275532.
KOK02569.
OMAYQEYMET.
ProtClustDBPRK10617.

Family and domain databases

InterProIPR011031. Multihaem_cyt.
IPR024717. NapC/NirT/NrfH.
IPR005126. NapC/NirT_cyt_c_N.
IPR011885. NO3Rdtase_cyt_c_NapC/NirT.
[Graphical view]
PfamPF03264. Cytochrom_NNT. 1 hit.
[Graphical view]
PIRSFPIRSF000013. 4_hem_cytochrm_NapC. 1 hit.
TIGRFAMsTIGR02161. napC_nirT. 1 hit.
PROSITEPS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNAPC_ECOL6
AccessionPrimary (citable) accession number: P0ABL6
Secondary accession number(s): P33932
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
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