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Protein

Cell division protein FtsA

Gene

ftsA

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.UniRule annotation

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsAUniRule annotation
Gene namesi
Name:ftsAUniRule annotation
Ordered Locus Names:Z0104, ECs0098
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation
  • Note: Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphiphatic helix.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000627351 – 420Cell division protein FtsAAdd BLAST420

Proteomic databases

PRIDEiP0ABH2

Interactioni

Subunit structurei

Self-interacts. Interacts with FtsZ.UniRule annotation

Protein-protein interaction databases

STRINGi155864.Z0104

Structurei

3D structure databases

ProteinModelPortaliP0ABH2
SMRiP0ABH2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FtsA/MreB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CIT Bacteria
COG0849 LUCA
HOGENOMiHOG000049205
KOiK03590
OMAiVIPFGGN

Family and domain databases

HAMAPiMF_02033 FtsA, 1 hit
InterProiView protein in InterPro
IPR020823 Cell_div_FtsA
IPR003494 SHS2_FtsA
PfamiView protein in Pfam
PF02491 SHS2_FTSA, 1 hit
PIRSFiPIRSF003101 FtsA, 1 hit
SMARTiView protein in SMART
SM00842 FtsA, 1 hit
TIGRFAMsiTIGR01174 ftsA, 1 hit

Sequencei

Sequence statusi: Complete.

P0ABH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKATDRKLV VGLEIGTAKV AALVGEVLPD GMVNIIGVGS CPSRGMDKGG
60 70 80 90 100
VNDLESVVKC VQRAIDQAEL MADCQISSVY LALSGKHISC QNEIGMVPIS
110 120 130 140 150
EEEVTQEDVE NVVHTAKSVR VRDEHRVLHV IPQEYAIDYQ EGIKNPVGLS
160 170 180 190 200
GVRMQAKVHL ITCHNDMAKN IVKAVERCGL KVDQLIFAGL ASSYSVLTED
210 220 230 240 250
ERELGVCVVD IGGGTMDIAV YTGGALRHTK VIPYAGNVVT SDIAYAFGTP
260 270 280 290 300
PSDAEAIKVR HGCALGSIVG KDESVEVPSV GGRPPRSLQR QTLAEVIEPR
310 320 330 340 350
YTELLNLVNE EILQLQEKLR QQGVKHHLAA GIVLTGGAAQ IEGLAACAQR
360 370 380 390 400
VFHTQVRIGA PLNITGLTDY AQEPYYSTAV GLLHYGKESH LNGEAEVEKR
410 420
VTASVGSWIK RLNSWLRKEF
Length:420
Mass (Da):45,330
Last modified:January 1, 1988 - v1
Checksum:iC2475377A229B982
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG54398.1
BA000007 Genomic DNA Translation: BAB33521.1
PIRiB85492
B90641
RefSeqiNP_308125.1, NC_002695.1
WP_000588474.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG54398; AAG54398; Z0104
BAB33521; BAB33521; BAB33521
GeneIDi913567
KEGGiece:Z0104
ecs:ECs0098
PATRICifig|386585.9.peg.198

Similar proteinsi

Entry informationi

Entry nameiFTSA_ECO57
AccessioniPrimary (citable) accession number: P0ABH2
Secondary accession number(s): P06137, Q47229
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 1, 1988
Last modified: April 25, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health