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Protein

Cell division protein FtsA

Gene

ftsA

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division

Enzyme and pathway databases

BioCyciECOO157:FTSA-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsAUniRule annotation
Gene namesi
Name:ftsAUniRule annotation
Ordered Locus Names:Z0104, ECs0098
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation

  • Note: Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphiphatic helix.UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000627351 – 420Cell division protein FtsAAdd BLAST420

Proteomic databases

PRIDEiP0ABH2.

Interactioni

Subunit structurei

Self-interacts. Interacts with FtsZ.UniRule annotation

Protein-protein interaction databases

MINTiMINT-112959.
STRINGi155864.Z0104.

Structurei

3D structure databases

ProteinModelPortaliP0ABH2.
SMRiP0ABH2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FtsA/MreB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CIT. Bacteria.
COG0849. LUCA.
HOGENOMiHOG000049205.
KOiK03590.
OMAiVIPFGGN.

Family and domain databases

HAMAPiMF_02033. FtsA. 1 hit.
InterProiIPR020823. Cell_div_FtsA.
IPR003494. SHS2_FtsA.
[Graphical view]
PfamiPF02491. SHS2_FTSA. 1 hit.
[Graphical view]
PIRSFiPIRSF003101. FtsA. 1 hit.
SMARTiSM00842. FtsA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01174. ftsA. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ABH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKATDRKLV VGLEIGTAKV AALVGEVLPD GMVNIIGVGS CPSRGMDKGG
60 70 80 90 100
VNDLESVVKC VQRAIDQAEL MADCQISSVY LALSGKHISC QNEIGMVPIS
110 120 130 140 150
EEEVTQEDVE NVVHTAKSVR VRDEHRVLHV IPQEYAIDYQ EGIKNPVGLS
160 170 180 190 200
GVRMQAKVHL ITCHNDMAKN IVKAVERCGL KVDQLIFAGL ASSYSVLTED
210 220 230 240 250
ERELGVCVVD IGGGTMDIAV YTGGALRHTK VIPYAGNVVT SDIAYAFGTP
260 270 280 290 300
PSDAEAIKVR HGCALGSIVG KDESVEVPSV GGRPPRSLQR QTLAEVIEPR
310 320 330 340 350
YTELLNLVNE EILQLQEKLR QQGVKHHLAA GIVLTGGAAQ IEGLAACAQR
360 370 380 390 400
VFHTQVRIGA PLNITGLTDY AQEPYYSTAV GLLHYGKESH LNGEAEVEKR
410 420
VTASVGSWIK RLNSWLRKEF
Length:420
Mass (Da):45,330
Last modified:January 1, 1988 - v1
Checksum:iC2475377A229B982
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG54398.1.
BA000007 Genomic DNA. Translation: BAB33521.1.
PIRiB85492.
B90641.
RefSeqiNP_308125.1. NC_002695.1.
WP_000588474.1. NZ_LPWC02000002.1.

Genome annotation databases

EnsemblBacteriaiAAG54398; AAG54398; Z0104.
BAB33521; BAB33521; BAB33521.
GeneIDi913567.
KEGGiece:Z0104.
ecs:ECs0098.
PATRICi18349138. VBIEscCol44059_0099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG54398.1.
BA000007 Genomic DNA. Translation: BAB33521.1.
PIRiB85492.
B90641.
RefSeqiNP_308125.1. NC_002695.1.
WP_000588474.1. NZ_LPWC02000002.1.

3D structure databases

ProteinModelPortaliP0ABH2.
SMRiP0ABH2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-112959.
STRINGi155864.Z0104.

Proteomic databases

PRIDEiP0ABH2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG54398; AAG54398; Z0104.
BAB33521; BAB33521; BAB33521.
GeneIDi913567.
KEGGiece:Z0104.
ecs:ECs0098.
PATRICi18349138. VBIEscCol44059_0099.

Phylogenomic databases

eggNOGiENOG4105CIT. Bacteria.
COG0849. LUCA.
HOGENOMiHOG000049205.
KOiK03590.
OMAiVIPFGGN.

Enzyme and pathway databases

BioCyciECOO157:FTSA-MONOMER.

Family and domain databases

HAMAPiMF_02033. FtsA. 1 hit.
InterProiIPR020823. Cell_div_FtsA.
IPR003494. SHS2_FtsA.
[Graphical view]
PfamiPF02491. SHS2_FTSA. 1 hit.
[Graphical view]
PIRSFiPIRSF003101. FtsA. 1 hit.
SMARTiSM00842. FtsA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01174. ftsA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFTSA_ECO57
AccessioniPrimary (citable) accession number: P0ABH2
Secondary accession number(s): P06137, Q47229
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 1, 1988
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.