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Protein

Ethanolamine utilization protein EutM

Gene

eutM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place.

Pathway:iethanolamine degradation

This protein is involved in the pathway ethanolamine degradation, which is part of Amine and polyamine degradation.
View all proteins of this organism that are known to be involved in the pathway ethanolamine degradation and in Amine and polyamine degradation.

GO - Molecular functioni

  • structural molecule activity Source: EcoCyc

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7287-MONOMER.
ECOL316407:JW2441-MONOMER.
UniPathwayiUPA00560.

Names & Taxonomyi

Protein namesi
Recommended name:
Ethanolamine utilization protein EutM
Gene namesi
Name:eutM
Synonyms:cchA, yffZ
Ordered Locus Names:b2457, JW2441
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318 Componenti: Chromosome UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14187. eutM.

Subcellular locationi

GO - Cellular componenti

  • ethanolamine degradation polyhedral organelle Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence AnalysisAdd
BLAST
Chaini26 – 9772Ethanolamine utilization protein EutMPRO_0000004786Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-9537N.
IntActiP0ABF4. 2 interactions.
STRINGi511145.b2457.

Structurei

Secondary structure

1
97
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 119Combined sources
Helixi12 – 2514Combined sources
Beta strandi26 – 3510Combined sources
Beta strandi40 – 478Combined sources
Helixi49 – 6618Combined sources
Beta strandi69 – 779Combined sources
Helixi81 – 855Combined sources
Beta strandi90 – 923Combined sources
Turni94 – 974Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3I6PX-ray2.10A/B/C/D/E/F1-97[»]
3MPWX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L1-97[»]
3MPYX-ray2.00A1-97[»]
ProteinModelPortaliP0ABF4.
SMRiP0ABF4. Positions 2-97.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0ABF4.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG4577.
HOGENOMiHOG000286836.
InParanoidiP0ABF4.
KOiK04027.
OMAiPHSEVEL.
OrthoDBiEOG6ZH2H4.
PhylomeDBiP0ABF4.

Family and domain databases

InterProiIPR020808. Bact_microcomp_CS.
IPR000249. Microcompartment_bac.
[Graphical view]
PfamiPF00936. BMC. 1 hit.
[Graphical view]
SMARTiSM00877. BMC. 1 hit.
[Graphical view]
PROSITEiPS01139. BACT_MICROCOMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0ABF4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEALGMIETR GLVALIEASD AMVKAARVKL VGVKQIGGGL CTAMVRGDVA
60 70 80 90
ACKAATDAGA AAAQRIGELV SVHVIPRPHG DLEEVFPIGL KGDSSNL
Length:97
Mass (Da):9,866
Last modified:October 25, 2005 - v1
Checksum:i0A4170FD8ABB8CF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75510.2.
AP009048 Genomic DNA. Translation: BAA16335.2.
RefSeqiNP_416952.2. NC_000913.3.
WP_000387713.1. NZ_CP010445.1.

Genome annotation databases

EnsemblBacteriaiAAC75510; AAC75510; b2457.
BAA16335; BAA16335; BAA16335.
GeneIDi946942.
KEGGieco:b2457.
PATRICi32120297. VBIEscCol129921_2551.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75510.2.
AP009048 Genomic DNA. Translation: BAA16335.2.
RefSeqiNP_416952.2. NC_000913.3.
WP_000387713.1. NZ_CP010445.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3I6PX-ray2.10A/B/C/D/E/F1-97[»]
3MPWX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L1-97[»]
3MPYX-ray2.00A1-97[»]
ProteinModelPortaliP0ABF4.
SMRiP0ABF4. Positions 2-97.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-9537N.
IntActiP0ABF4. 2 interactions.
STRINGi511145.b2457.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75510; AAC75510; b2457.
BAA16335; BAA16335; BAA16335.
GeneIDi946942.
KEGGieco:b2457.
PATRICi32120297. VBIEscCol129921_2551.

Organism-specific databases

EchoBASEiEB3939.
EcoGeneiEG14187. eutM.

Phylogenomic databases

eggNOGiCOG4577.
HOGENOMiHOG000286836.
InParanoidiP0ABF4.
KOiK04027.
OMAiPHSEVEL.
OrthoDBiEOG6ZH2H4.
PhylomeDBiP0ABF4.

Enzyme and pathway databases

UniPathwayiUPA00560.
BioCyciEcoCyc:G7287-MONOMER.
ECOL316407:JW2441-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP0ABF4.
PROiP0ABF4.

Family and domain databases

InterProiIPR020808. Bact_microcomp_CS.
IPR000249. Microcompartment_bac.
[Graphical view]
PfamiPF00936. BMC. 1 hit.
[Graphical view]
SMARTiSM00877. BMC. 1 hit.
[Graphical view]
PROSITEiPS01139. BACT_MICROCOMP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiEUTM_ECOLI
AccessioniPrimary (citable) accession number: P0ABF4
Secondary accession number(s): P77606
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 25, 2005
Last modified: July 22, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.